MedicalResearch.com Interview with:
Dina Kao, MD, FRCPC
Division of Gastroenterology, Department of Medicine
University of Alberta
Edmonton, Alberta, Canada
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: We wanted to see what would be the best way to deliver fecal microbiota transplantation (FMT.)
There were many controlled studies of FMT delivered by various methods, showing different success rates. Not only were the route of delivery different, but the amount of donor stools also varied greatly from study to study. It appeared that most of the studies delivered by the upper routes gave a smaller amount of donor stool compared to the studies delivering FMT by colonoscopy.
Our hypothesis was that given the same amount of donor stool, the effectiveness would be similar by capsules and by colonsocopy.