Many Parents Who Refuse Infant Vitamin K Refuse All Vaccinations For Their Children interview with:
Dr. Shannon MacDonald PhD
Department of Pediatrics, University of Calgary, Calgary and
Faculty of Nursing, University of Alberta, Edmonton, Alberta, Canada

Medical Research: What are the main findings of the study?

Dr. MacDonald: We found that vitamin K was refused by only a very small number of parents in our study population (0.3%) but that the number appears to be increasing (almost doubling in the past 7 years). The parents that refused vitamin K for their child were more likely to be those that delivered at home and/or with a midwife. We also found that parents who refused vitamin K for their child were also much more likely to go on to refuse all vaccinations by 15 months of age.

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Dietary Vitamin K Linked to Lower Heart Disease, Cancer Mortality Interview with
Mònica Bulló PhD
Human Nutrition Unit Department of Biochemistry & Biotechnology
IISPV  School of Medicine
Rovira i Virgili University
Sant Llorenç, Spain What are the main findings of the study?

Dr Bulló: There is some evidence that different dietary forms of vitamin K could exert varying effects on health, however no study to date has simultaneously evaluated the potential effects of the main vitamin K forms on cancer and cardiovascular mortality. We conducted a prospective, epidemiologic study involving 7,216 elderly subjects at high cardiovascular risk who were followed for about 5 years.The results of the present study show, for the first time that an increase in dietary intake of both forms of vitamin K is related to a lower risk of cardiovascular mortality, cancer mortality or all-cause mortality.

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Diabetes: Marker for Poor Vitamin K Status Reflects Increased Cardiovascular Risk Interview with: Gerdien Dalmeijer

Postdoc | Julius Centrum | Universitair Medisch Centrum Utrecht
Kamernummer STR. 6.119 | Huispostnummer STR. 6.131 |
Postbus 85500| 3508GA UTRECHT What are the main findings of the study?

Answer: The main findings of our prospective study among type 2 diabetes patients show that high circulating desphospho-uncarboxylated matrix Gla protein (dp-ucMGP) concentrations, reflecting a poor vitamin K status, are associated with increased cardiovascular disease risk, especially with peripheral arterial disease and heart failure. These results suggest that a poor vitamin K status is associated with increased cardiovascular disease risk. Were any of the findings unexpected?

Answer: To our knowledge, this is the first study investigating the association of circulating MGP species with the risk of cardiovascular events; thus far only the association between dp-ucMGP and calcification has been investigated. Several studies but not all have shown that high dp-ucMGP concentrations are associated with increased calcification. We now extend these findings by showing the high circulating dp-ucMGP concentration is also associated with increased CVD risk, especially with peripheral arterial disease and heart failure.

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