MedicalResearch.com Interview with:
Deborah Watkins Bruner RN, PhD, FAAN
Senior Vice President of Research
Professor and Robert W. Woodruff Chair in Nursing
Nell Hodgson Woodruff School of Nursing
Professor, Department of Radiation Oncology
Emory University School of Medicine
MedicalResearch.com: What is the background for this study?
Response: In a randomized clinical trial entitled, “Quality of Life in Patients With Low-Risk Prostate Cancer Treated With Hypofractionated vs Conventional Radiotherapy” the NRG Oncology Group previously demonstrated that men with low risk prostate cancer had similar 5-year disease- free survival of about 85% when treated with either conventional radiotherapy (C-RT) of 73.8 Gy in 41 fractions over 8.2 weeks, or with hypofractionated radiotherapy (H-RT) of 70 Gy in 28 fractions over 5.6 weeks. However, late physician reported side effects of mild bowel and bladder symptoms were increased in patients treated with H-RT and raised questions if the H-RT arm is acceptable to patients.
The current study asked the patient’s directly about their bowel, bladder, sexual function, anxiety, depression and general quality of life using valid patient reported questionnaires. These questionnaires have been found to be more accurate for reporting patient symptoms than physician report alone.