Lael S. Reinstatler, MD, MPH.PGY 4 Urology ResidencyDartmouth Hitchcock

HPV6 Serology Associated with Bladder Cancer

MedicalResearch.com Interview with:

Lael S. Reinstatler, MD, MPH.PGY 4 Urology ResidencyDartmouth Hitchcock

Dr. Reinstatler


Lael S
Reinstatler, MD, MPH.
PGY 4 Urology Residency
Dartmouth Hitchcock

MedicalResearch.com: What is the background for this study? What are the main findings? 

Response: Human Papillomavirus is an oncogenic virus associated with other genitourinary cancers including penile cancer.

HPV is detectable in urine and in urethral swabs and it interacts with stratified squamous epithelium which lines the majority of the genitourinary tract. Prior research has identified HPV in bladder tumors but detection methods are inconsistent.

In this study, we looked for an association with HPV serology (indicating prior HPV systemic exposure) and bladder cancer.

MedicalResearch.com: What should readers take away from your report? 

Response: The present study identified an association of positive HPV6 serology with bladder cancer. This may represent a different way of researching the possible link between HPV and bladder cancer and opens new doors for study. More information is needed including elucidating the oncogenic pathway, if any, that HPV may have in the urinary tract. As this was a large population-based analysis, the HPV6 association observed may be a marker for another unknown risk factor associated with bladder cancer. Future work is certainly warranted.  

MedicalResearch.com: What recommendations do you have for future research as a result of this work?

Response: We plan on extending this research into other cohorts. The current research is from a survey based study of US adults but more data is needed with other HPV subtypes and with specific stages and grades of bladder cancer.We have no disclosures.  

Citation:

Reinstatler, Lael & Shee, Kevin & Stensland, Kristian & Dagrosa, Lawrence & Seigne, John & Sverrisson, Einar. (2019). MP05-12 RE-EXAMINING AN OLD TREND: THE ASSOCIATION OF HUMAN PAPILLOMAVIRUS AND BLADDER CANCER. Journal of Urology. 201. 10.1097/01.JU.0000554983.38815.b7.

[wysija_form id=”3″]

 

May 13, 2019 @ 7:18 pm 

The information on MedicalResearch.com is provided for educational purposes only, and is in no way intended to diagnose, cure, or treat any medical or other condition. Always seek the advice of your physician or other qualified health and ask your doctor any questions you may have regarding a medical condition. In addition to all other limitations and disclaimers in this agreement, service provider and its third party providers disclaim any liability or loss in connection with the content provided on this website.

 

No Comments

Post A Comment

This site uses Akismet to reduce spam. Learn how your comment data is processed.