Diabetics with Acute Myocardial Infarction Have Higher Mortality

MedicalResearch.com Interview with:
Jorge F. Saucedo MD
Allstate Foundation, Judson B. Branch Chair of Cardiology
Head, Division of Cardiology
Co-Director Cardiovascular Institute
NorthShore University HealthSystem
Clinical Professor of Medicine
University of Chicago Pritzker School of Medicine

Talla A. Rousan, MD
Oklahoma City, OK.
First author of study.

Medical Research: What are the main findings of the study?

Answer: It was found that patients with diabetes mellitus (DM) presenting with acute myocardial infarction (AMI) have a higher in-hospital mortality rate compared to patients without DM. Patients with insulin-requiring diabetes mellitus presenting with non-ST-segment elevation myocardial infarction had higher in-hospital mortality rate than patients with non-insulin requiring diabetes mellitus.

Medical Research: What was most surprising about the results?

Answer: We were surprised to find that despite the advancement in the interventional and medical techniques in the management of AMI, patients with diabetes mellitus continue to have worse in-hospital outcomes.

Medical Research: What should clinicians and patients take away from your report?

Answer: Patients with diabetes mellitus presenting with acute myocardial infarction are undertreated and tend to have worse in-hospital outcomes.

Care must be undertaken to ensure that this group of patients is receiving guideline-directed therapy and optimal clinical care.

Although not specifically studied in our report, a multidisciplinary approach with both cardiologists and endocrinologists (both on inpatient and outpatient basis) may be of benefit to patients with DM presenting with acute myocardial infarction.

Medical Research: What recommendations do you have for future research as a result of this study?

Answer: Additional research studies are needed to determine the influence of specific therapies for patients with diabetes mellitus presenting with AMI, specifically patients with insulin-requiring diabetes mellitus. In addition, although our study did not show any clinically significant difference in patients with newly diagnosed diabetes mellitus(Hemoglobin A1C > 6.5%) presenting with acute myocardial infarction, further in-depth studies are in need to look at this group of patients.


Talla A. Rousan, Reji M. Pappy, Anita Y. Chen, Matthew T. Roe, Jorge F. Saucedo
American Journal of Cardiology, Vol. 114, Issue 8, p1136–1144
Published online: July 29, 2014



Last Updated on September 29, 2014 by Marie Benz MD FAAD