Insulin Pump Therapy May Be Superior to Multiple Injections in Young People With Type 1 Diabetes Interview with:
Prof. Dr. med. Reinhard Holl
Division of Endocrinology and Diabetes, Medical Faculty
Aachen University, Aachen,
Institute of Epidemiology and Medical Biometry
University of Ulm, Ulm
Germany What is the background for this study? What are the main findings?

Response: Today there are two accepted strategies to treat type-1 diabetes: pump or multiple daily injections. In a large group of patients we compared both strategies, and our results indicate advantages for pump therapy with fewer severe hypos, fewer events of diabetic ketoacidosis, and better metabolic control. What should clinicians and patients take away from your report?

Response: For children, adolescents and young adults, pump therapy may be superior to multiple daily injections as a treatment strategy for type-1 diabetes. This information may help decisions by patients, families and medical caregivers. What recommendations do you have for future research as a result of this study?

Response: Future research might focus on the use of continuous glucose monitoring, together with either pump or multiple daily injections therapy. Is there anything else you would like to add?

Response: This analysis was based on routine data from Germany, Austria and Luxemburg, with co-authors from all three countries. One co-author reported previous lectures supported by different pharmaceutical companies, the other authors had no conflict of interest. Thank you for your contribution to the community.


Karges B, Schwandt A, Heidtmann B, Kordonouri O, Binder E, Schierloh U, Boettcher C, Kapellen T, Rosenbauer J, Holl RW. Association of Insulin Pump Therapy vs Insulin Injection Therapy With Severe Hypoglycemia, Ketoacidosis, and Glycemic Control Among Children, Adolescents, and Young Adults With Type 1 Diabetes. JAMA. 2017;318(14):1358–1366. doi:10.1001/jama.2017.13994

Note: Content is Not intended as medical advice. Please consult your health care provider regarding your specific medical condition and questions.

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Last Updated on October 18, 2017 by Marie Benz MD FAAD