15 May Father’s Age Linked To Pregnancy Problems and Childhood Disorders

MedicalResearch.com Interview with:

Dr. Phillips

Nancy Phillips, MD
Clinical Assistant Professor
Rutgers Robert Wood Johnson Medical School
Women’s Health Institute
New Brunswick, NJ

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: The background of this article was as an interest piece prompting a literature review. We both felt it represented an underserved clinical need.

The main findings are that the paternal age at conception does impact pregnancy outcomes,  including pregnancy complications, fetal chromosomal anomalies and childhood cancers and psychological disorders.

MedicalResearch.com: What should readers take away from your report?

Response: Readers should take away that reproductive outcomes are not solely based on the mother in regard to age. Although Maternal age likely has much more overall impact, paternal age should be considered. Men need to be aware that they may have a “biological clock” as well.

MedicalResearch.com: What recommendations do you have for future research as a result of this work?

Response: Further research needs to be addressed, not only in outcomes, but in possible interventions, including cost/benefit analysis of sperm banking.  Public and physician awareness needs to be assessed and potentially improved, so adequate and accurate counseling can occur.

MedicalResearch.com: Is there anything else you would like to add?

Response:  One last though would be that this  article is not meant to scare anyone. As in women of advanced maternal age, men of advanced paternal age are still much more likely to have a successful pregnancy with a good outcome. 

Citation:

Phillips, L. Taylor, G. Bachmann. Maternal, infant and childhood risks associated with advanced paternal age: The need for comprehensive counseling for men. Maturitas, 2019; 125: 81 DOI: 10.1016/j.maturitas.2019.03.020

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Last Updated on May 15, 2019 by Marie Benz MD FAAD