22 Nov More Surgeries, Fewer Deaths From Abdominal Aortic Aneurysms in US than UK

MedicalResearch.com Interview with:

Dr. Alan Karthikesalingam

Alan Karthikesalingam MD PhD, NIHR
Academic Clinical Lecturer in Vascular Surgery
St George’s Vascular Institute
London, UK

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: The background for this study was that the typical diameter at abdominal aortic aneurysm (AAA)  repair, and the population incidence of AAA repair, have been known to vary considerably between different countries. This study aimed to observe whether a discrepancy in the population incidence rate of AAA repair between England and the USA was seen alongside a discrepancy in population rates of AAA-related mortality or AAA rupture in those countries.

MedicalResearch.com: What should readers take away from your report?

Response: Readers should take away that the rate of  abdominal aortic aneurysm repair in the USA was significantly higher than in England and that AAA were typically repaired at smaller diameter in the USA, while at a population level AAA-related death or AAA rupture were both significantly more common in England.

MedicalResearch.com: What recommendations do you have for future research as a result of this study?

Response: Future research could establish whether an association between AAA repair rate and the national rate of AAA rupture (or AAA-related mortality) is seen across a wider analysis of data from several countries. Future research could also aim to establish whether non-operative rates are associated with population AAA-related mortality at more local level.

MedicalResearch.com: Thank you for your contribution to the MedicalResearch.com community.

Citation:

Thresholds for Abdominal Aortic Aneurysm Repair in England and the United States

Alan Karthikesalingam, Ph.D., M.R.C.S., Alberto Vidal-Diez, Ph.D., Peter J. Holt, Ph.D., F.R.C.S., Ian M. Loftus, M.D.(Res.), F.R.C.S., Marc L. Schermerhorn, M.D., Peter A. Soden, M.D., Bruce E. Landon, M.D., and Matthew M. Thompson, M.D.(Res.), F.R.C.S.

N Engl J Med 2016; 375:2051-2059November 24, 2016DOI: 10.1056/NEJMoa1600931

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Last Updated on November 24, 2016 by Marie Benz MD FAAD