Migraine with Aura Linked to Cardiovascular Disease Risk

MedicalResearch.com Interview with:
Tobias Kurth, MD, ScD (Pronouns: he/him)
Professor of Public Health and Epidemiology
Director, Institute of Public Health
Charité – Universitätsmedizin Berlin 

MedicalResearch.com: What is the background for this study?

Response: Migraine (with aura) has been associated with increased risk of cardiovascular disease but its absolute contribution in relation to other major vascular risk factors was not unclear.

MedicalResearch.com: What are the main findings?

Response: Our study finds that among women (as we only studied women) migraine with aura is a strong absolute contributor to cardiovascular disease. While elevated systolic blood pressure, currently smoking and having diabetes are the strongest absolute contributors, migraine with aura was a stronger contributor as, for example, being obese or having high lipid values.

MedicalResearch.com: What should readers take away from your report? 

Response: That migraine with aura should be considered an important risk marker for increased risk of cardiovascular disease.

MedicalResearch.com: What recommendations do you have for future research as a result of this work?

Response: Future research should help to understand whether strategies to treat migraine help preventing cardiovascular disease. We also need to understand whether our findings can also be found in men. 

MedicalResearch.com: Is there anything else you would like to add?

Response: Please see the full disclosures in the paper. My disclosures are: fees from Eli Lilly, Newsenslab, CoLucid, Total, Novartis, and Daiinchi Sanko and a grant from Amgen as well as personal fees from The BMJ. 


Kurth T, Rist PM, Ridker PM, Kotler G, Bubes V, Buring JE. Association of Migraine With Aura and Other Risk Factors With Incident Cardiovascular Disease in Women. JAMA. 2020;323(22):2281–2289. doi:10.1001/jama.2020.7172


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Last Updated on June 11, 2020 by Marie Benz MD FAAD