19 Dec Protein Loss in Urine Associated With Increased Risk of Dementia

MedicalResearch.com Interview with:

Kay Deckers

Kay Deckers, MSc
PhD student
School for Mental Health and Neuroscience
Department of Psychiatry and Neuropsychology
Maastricht University
The Netherlands

MedicalResearch.com: What is the background for this study?

Response: In an earlier review (https://www.ncbi.nlm.nih.gov/pubmed/25504093), we found that renal dysfunction was one the new candidate risk factors of dementia and needed further investigation.

MedicalResearch.com: What are the main findings?

Response: Albuminuria is associated with an increased risk of developing cognitive impairment or dementia.

MedicalResearch.com: What should readers take away from your report?

Response: The association between renal dysfunction and dementia is not causal. It is only one part of the jigsaw in the complex etiology of dementia.

MedicalResearch.com: What recommendations do you have for future research as a result of this study?

Response: Future research should examine whether the association between albuminuria and dementia is causal or due to shared mechanisms. Additionally, future studies should establish the underlying pathophysiology.

MedicalResearch.com: Thank you for your contribution to the MedicalResearch.com community.

Citation:
Kay Deckers, Ileana Camerino, Martin P.J. van Boxtel, Frans R.J. Verhey, Kate Irving, Carol Brayne, Miia Kivipelto, John M. Starr, Kristine Yaffe, Peter W. de Leeuw, and Sebastian Köhler. Dementia risk in renal dysfunction: A systematic review and meta-analysis of prospective studies. Neurology, December 2016
DOI: 10.1212/WNL.0000000000003482%0D

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Last Updated on December 19, 2016 by Marie Benz MD FAAD