11 Feb Recommendations To Restrict Dietary Fat Not Supported By Clinical Trials
Medical Research: What is the background for this study? What are the main findings
Response: There were 6 randomized controlled dietary trials performed before the government dietary fat recommendations were released. When we performed a systematic review and meta-analysis of the available trials at this time, there was no significant difference in all-cause mortality or cardiovascular heart disease mortality. In essence, there was no support from randomized controlled trials at the time to support a reduction in fat and saturated fat (and there still isn’t from recent meta-analysis including newer trials).
The reductions in mean serum cholesterol levels were significantly higher in the intervention groups but this did not result in significant differences in cardiovascular heart disease or all-cause mortality.
Medical Research: What should clinicians and patients take away from your report?
Response: Recommendations to restrict saturated fat or total fat in the diet that began back in the late 1970s and early 1980s were not supported by the randomized clinical trials at the time, and in fact are still not supported by the randomized control trial evidence in the current-day.
Medical Research: What recommendations do you have for future research as a result of this study?
Response: Future research should target added sugars, which are likely dietary culprit involved in early mortality and cardiovascular heart disease mortality.
MedicalResearch.com Interview with:, & James J. DiNicolantonio, PharmD (2015). Recommendations To Restrict Dietary Fat Not Supported By Clinical Trials MedicalResearch.com