Contact Allergic Reactions to Implanted Cardiac Devices

MedicalResearch.com Interview with:

Amber Reck Atwater, M.D.Dermatology Residency Program DirectorAssociate Professor of DermatologyDirector, Contact Dermatitis ClinicDuke Dermatology

Dr. Reck Atwater

Amber Reck Atwater, M.D.
Dermatology Residency Program Director
Associate Professor of Dermatology
Director, Contact Dermatitis Clinic
Duke Dermatology 

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: We completed an evaluation of our Duke Dermatology patients who underwent patch testing for possible allergy to their cardiac devices – pacemakers and defibrillators.

From March 1, 2012 to September 15, 2017 we saw 11 patients with suspected allergy to their devices.  Concern for allergy, skin eruption, skin symptoms, and concern for infection were common. 73% of patients had erythema at their implant scars; pruritus and pain were also noted.  Six of our patients had relevant reactions, and the most common allergies were metals, silicone and rubber accelerators.  Continue reading

Is Your Car’s Electric Motor a Shock to Your Heart?

MedicalResearch.com Interview with:
Dr. med. Carsten Lennerz, M.Sc.

Deutsches Herzzentrum München
München 

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: Knowing that strong electric motors cause electromagnetic fields (EM) and  that CIED (Cardiac implanted electronic devices) may malfunction due to electromagnetic fields raises serious concerns when electric cars are considered. Moreover the use of electric cars for private and public transport is increasing and thus the question of safety is becoming more and more important.

108 CIED patients drove and charged 4 commercially available e-cars on a roller bench test (simulating road driving in a safe environment). There were no adverse events and no electromagnetic interference was detected during driving or charging of the cars.

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How a PET Can Save Your Heart

MedicalResearch.com Interview with:

Dr-W-Robert-Taylor

Dr. Taylor

Robert Taylor, MD, PhD
Marcus Chair in Vascular Medicine
Executive Vice Chair, Medicine
Director, Division of Cardiology
Professor of Medicine and
Biomedical Engineering
Emory University School of Medicine

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: The early identification and localization of bacterial infections is a critical step for initiating effective treatment.   This is particularly challenging in the setting of infections associated with implanted medical devices.  We have developed a highly specific probe for bacteria that is based on the fact that bacteria have a specific system for taking up maltodextrins which are polysaccharides that mammalian cells cannot take up directly.  We can label this probe with either a fluorescent of radioactive tag that allows visualization of the bacteria.

In the current article, we have used an animal model of implantable cardiac devices to demonstrate that our probe is very specific and sensitive for detecting bacterial infections.  It is worth noting that these are subclinical infections that could not be detected by any other means except for surgical removal.

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