Author Interviews, Cancer Research, Colon Cancer, JAMA, USPSTF / 26.05.2021

MedicalResearch.com Interview with: Martha Kubik, Ph.D., R.N. Professor and Director School of Nursing College of Health and Human Services George Mason University MedicalResearch.com: What is the background for this study? Response: Colorectal cancer is the third leading cause of cancer deaths in the United States, yet about a quarter of people ages 50 to 75 have never been screened for this devastating disease. Fortunately, we know that screening for colorectal cancer is effective and saves lives. New science about colorectal cancer in people younger than 50 years old has enabled us to expand our previous guidelines to recommend that all adults ages 45 to 75 be screened for colorectal cancer to reduce their risk of dying from this disease. (more…)
Author Interviews, Brigham & Women's - Harvard, Colon Cancer, Gastrointestinal Disease, Sugar / 06.05.2021

MedicalResearch.com Interview with: Jinhee Hur, PhD Research Fellow Department of Nutrition Harvard T.H. Chan School of Public Health Boston, MA 02115 MedicalResearch.com: What is the background for this study? Response: Early-onset colorectal cancer (EO-CRC, age <50 years at diagnosis) is rapidly rising in the US since the mid-1980s, with an unclear understanding of its etiology and contributors to the rise. Sugar-sweetened beverages (SSBs) exert adverse metabolic repercussions throughout the life course, including insulin resistance and inflammation. Higher SSB intake can induce obesity, which has been linked to risk of EO-CRC. A recent experimental study also suggests that high fructose corn syrup, a primary sweetener in SSBs, may promote colon tumor growth, independent of metabolic dysregulation. In the US, SSB consumption has dramatically increased during the 2nd half of the 20th century, and adolescents and young adults have been the heaviest SSB drinkers across all age groups. Thus, we expect SSBs may be an emerging risk factor for EO-CRC and likely contribute to the rising incidence of EO-CRC. (more…)
Author Interviews, Brigham & Women's - Harvard, Cancer Research, Colon Cancer, Radiation Therapy / 04.05.2021

MedicalResearch.com Interview with: James Donald Byrne, Ph.D., M.D. Department of Radiation Oncology Massachusetts General Hospital Boston, Massachusetts MedicalResearch.com: What is the background for this study? Response: Radiation therapy is used as a treatment for more than half of all cancer patients and can be highly effective at shrinking tumors and killing cancer cells. But radiation treatment can also damage healthy tissue, including tissue in the mouth and gastrointestinal tract. This tissue injury can lead to oral mucositis, esophagitis, and proctitis — painful and sometimes debilitating tissue damage. It’s estimated that these injuries occur in over 200,000 patients in the U.S. each year. Our goal was to develop personalized shields that blocked radiation from affecting healthy GI tissue. (more…)