MedicalResearch.com Interview with:
E. van Eekelen, MSc | PhD Candidate
Leiden University Medical Center
Dept. Clinical Epidemiology
Leiden, The Netherlands
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Fatty liver, defined as excess accumulation of fat within the liver, covers a broad clinical spectrum and is the leading cause of chronic liver diseases. It has also been linked to type 2 diabetes and cardiovascular disease.
The consumption of alcohol is a well-established risk factor for fatty liver. However, we hypothesized that consumption of non-alcoholic energy-containing beverages also leads to liver fat accumulation. We analysed data from the Netherlands Epidemiology of Obesity (NEO) study, which is a prospective population-based cohort study including non-invasive measurements of liver fat content by magnetic resonance spectroscopy. Besides consumption of alcoholic beverages, sugar sweetened beverages were associated with more liver fat. We specifically showed that replacement of alcoholic beverages with milk was associated with less liver fat, whereas replacement with sugar sweetened beverages was associated with a similar amount of liver fat, even when taking calories into account. Continue reading