Author Interviews, Infections, Obstructive Sleep Apnea, Pediatrics / 18.02.2026

MedicalResearch.com Interview with: [caption id="attachment_72499" align="alignleft" width="174"]Dr. Alex Gileles-Hillel MDFounder and director of Gileles Lab Hadassah Medical Center Dr. Gileles-Hillel[/caption] Dr. Alex Gileles-Hillel MD Founder and director of Gileles Lab Hadassah Medical Center Along with Dr. Joel Reiter MD from the Faculty of Medicine Hebrew University and Senior Pediatric Pulmonologists at the Hadassah Medical Center with Dr. David Gozal MD, MBA, PhD from Marshall University MedicalResearch.com: What is the background for this study? Response: Children with Obstructive Sleep Apnea (OSA) experience increased morbidity, including cognitive difficulties, daytime dysfunction, and poorer academic performance, as well as a higher risk of future cardiometabolic disease such as hypertension and obesity. In addition, pediatric OSA has been shown to impair immune responses and alter immunologic function, although the clinical consequences of these changes remain incompletely understood.
Author Interviews, Sleep Disorders, Weight Research / 05.11.2025

[caption id="attachment_71296" align="aligncenter" width="500"]sleep-apnea-and-weight Photo by Kampus Production[/caption]

Introduction

Does your bed partner report loud snoring followed by periods of silence? Sleep apnoea occurs when throat muscles relax excessively during sleep, blocking airflow for 10 seconds or longer. Three modifiable factors—body weight, alcohol consumption, and sleeping position—directly influence how often these breathing interruptions occur and their severity. If you’re experiencing persistent snoring or disrupted sleep, consulting a sleep specialist Singapore can help determine which of these factors contribute most to your condition. Weight adds pressure to airways through neck fat deposits and abdominal pressure on the diaphragm. Alcohol relaxes throat muscles beyond normal sleep relaxation, increasing airway collapse. Back sleeping allows gravity to pull the tongue and soft tissues backward, narrowing the airway further. Addressing these factors may reduce apnoea episodes, sometimes reducing the need for continuous positive airway pressure (CPAP) therapy.
Sleep Disorders / 15.02.2025

A restful night’s sleep is essential for maintaining physical health, mental clarity, and daily productivity. However, sleep disorders like sleep apnoea can severely affect sleep quality, leading to various health issues. Fortunately, London is home to some of the world’s leading sleep specialists who provide expert diagnosis and treatment. In this article, we will explore what sleep apnoea is and how London’s sleep clinic offers effective solutions to manage and treat this condition. [caption id="attachment_66609" align="aligncenter" width="500"]sleep-apnea-snoring Photo by Kampus Production[/caption]

What is sleep apnoea?

Sleep apnoea is a sleep disorder that causes repeated interruptions in breathing during sleep. These pauses, known as apnoeas, can last from a few seconds to minutes and may occur multiple times an hour. This condition disrupts normal sleep patterns, leading to poor rest and long-term health risks. Sleep apnoea is generally classified into three main types. Obstructive sleep apnoea: Obstructive sleep apnoea is the most common form. It occurs when the throat muscles relax excessively, temporarily blocking the airway. This results in disrupted breathing patterns and frequent awakenings throughout the night. Central sleep apnoea: Central sleep apnoea is less common and occurs when the brain fails to send proper signals to the muscles that control breathing. Unlike obstructive sleep apnoea this type is not caused by airway obstruction but rather by a failure of the central nervous system to regulate breathing. Complex sleep apnoea syndrome: Complex Sleep Apnoea Syndrome, also known as treatment-emergent central sleep apnoea, is a combination of both obstructive sleep apnoea and central sleep apnoea. Individuals with this form of sleep apnoea experience characteristics of both conditions, making diagnosis and treatment more complex.
Obstructive Sleep Apnea / 28.10.2024

  aircurve-10-basics-bundle-items The ResMed AirSense™ 10 AutoSet™ Tri-Pack is an essential package designed for individuals with sleep apnea who require consistent and effective therapy. This article delves into the key features benefits and frequently asked questions surrounding the ResMed AirSense™ 10 AutoSet™ Tri-Pack offering a guide to help you understand its significance in sleep apnea treatment. What is the ResMed AirSense™ 10 AutoSet™ Tri-Pack? The ResMed AirSense™ 10 AutoSet™ Tri-Pack is a bundle that includes three essential items designed to optimize sleep apnea therapy. The package typically consists of the ResMed AirSense™ 10 AutoSet™ device a humidifier and heated tubing all aimed at improving the comfort and effectiveness of your CPAP therapy. The AutoSet feature ensures that the device automatically adjusts pressure levels based on your needs offering personalized treatment.
AHA Journals, Author Interviews, Obstructive Sleep Apnea, UCSF / 21.06.2021

MedicalResearch.com Interview with: [caption id="attachment_57673" align="alignleft" width="200"]Yerem Yeghiazarians, MD Professor of Medicine Leone-Perkins Family Endowed Chair in Cardiology San Francisco Board Past-President, American Heart Association Co-Director, Adult Cardiac Catheterization Laboratory Director, Peripheral Interventional Cardiology Program Director, Translational Cardiac Stem Cell Program Cardiovascular Research Institute Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research Associate Member in Experimental Therapeutics, UCSF Helen Diller Cancer Center University of California, San Francisco Dr. Yeghiazarians[/caption] Yerem Yeghiazarians, MD Professor of Medicine Leone-Perkins Family Endowed Chair in Cardiology San Francisco Board Past-President, American Heart Association Co-Director, Adult Cardiac Catheterization Laboratory Director, Peripheral Interventional Cardiology Program Director, Translational Cardiac Stem Cell Program Cardiovascular Research Institute Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research Associate Member in Experimental Therapeutics, UCSF Helen Diller Cancer Center University of California, San Francisco MedicalResearch.com: What is the background for this study? Response: Obstructive sleep apnea is very common, undiagnosed and undertreated. The AHA Scientific Statement was prepared to increase awareness amongst physicians and patients about this condition and to encourage more screening and therapy as appropriate. Obesity is certainly one of the significant risk factors for sleep apnea and we highlight this in the Scientific Statement: “The risk of OSA correlates with body mass index, and obesity remains the one major modifiable risk factor for OSA. In a population-based cohort study of 690 subjects, a 10% weight gain was associated with nearly 32% increase in the apnea-hypopnea index (AHI), and even modest weight control was effective in reducing the new occurrence of sleep-disordered breathing. An even stronger correlation exists between OSA and increased waist circumference and neck size. Neck sizes predisposing to OSA are usually >17 and 16 in for men and women, respectively.”
Author Interviews, Blood Pressure - Hypertension, Obstructive Sleep Apnea / 13.09.2019

MedicalResearch.com Interview with: Mireia Dalmases Cleries, MD Hospital Universitari Arnau de Vilanova and Santa Maria Group of Translational Research in Respiratory Medicine Lleida, Cataluña, Spain MedicalResearch.com: What is the background for this study? Response: Obstructive sleep apnea has been associated with poor blood pressure control and resistant hypertension. Moreover, it has been described that its treatment with continuous positive pressure (CPAP) could be an effective means of controlling blood pressure in this population. Nevertheless, studies assessing OSA prevalence, characteristics and association with blood pressure control in resistant hypertensive patients are limited and that’s the reason why we decided to perform this study.
Author Interviews, Obstructive Sleep Apnea / 22.10.2018

MedicalResearch.com Interview with: "Snoring away" by Doug Ford is licensed under CC BY 2.0Matthew P Butler, PhD Assistant Professor, Oregon Institute of Occupational Health Sciences Assistant Professor, Department of Behavioral Neuroscience Oregon Health & Science University Portland, OR 97239 MedicalResearch.com: What is the background for this study? What are the main findings? Response: Obstructive sleep apnea (OSA) is associated with heart disease and mortality, but how OSA does this is not well understood. We are therefore looking for sub-phenotypes within OSA that will help us predict who is at greatest risk. Current diagnosis of OSA is made on the basis of the apnea-hypopnea index (AHI – the number of respiratory events per hour of sleep). But the AHI is not a very good predictor of future mortality. We tested the hypothesis that the duration of events (how long the breathing interruptions are) would predict risk. We found that those with the shortest breathing interruptions had the highest risk of dying, after accounting for other conditions like age, gender, race, and smoking status. 
Alzheimer's - Dementia, Author Interviews, Obstructive Sleep Apnea, Sleep Disorders / 07.07.2018

MedicalResearch.com Interview with: “Woman sleeping” by Timothy Krause is licensed under CC BY 2.0Nathan E. Cross PhD, first author School of Psychology. Sharon L. Naismith, PhD, senior author Leonard P Ullman Chair in Psychology Brain and Mind Centre Neurosleep, NHMRC Centre of Research Excellence The University of Sydney, Australia  MedicalResearch.com: What is the background for this study? What are the main findings?  Response: Between 30 to 50% of the risk for dementia is due to modifiable risk factors such depression, hypertension, physical inactivity, obesity, diabetes and smoking. In recent years, multiple longitudinal cohort studies have observed a link between sleep apnoea and a greater risk (1.85 to 2.6 times more likely) of developing cognitive decline and dementia.  Furthermore, one study in over 8000 people also indicated that the presence of obstructive sleep apnoea (OSA) in older adults was associated with an earlier age of cognitive decline, and that treatment of OSA may delay the onset of cognitive impairment. This study reveals important insights into how sleep disorders such as OSA may impact the brain in older adults, as it is associated with widespread structural alterations in diverse brain regions. We found that reduced blood oxygen levels during sleep are related to reduced thickness of the brain's cortex in both the left and right temporal areas - regions that are important in memory and are early sites of injury in Alzheimer's disease. Indeed, reduced thickness in these regions was associated with poorer ability to learn new information, thereby being the first to link this structural change to memory decline.
Alzheimer's - Dementia, Author Interviews, NYU/NYMC, Obstructive Sleep Apnea / 15.11.2017

MedicalResearch.com Interview with: [caption id="attachment_38308" align="alignleft" width="150"]Ricardo S Osorio MD Center for Brain Health Department of Psychiatry Center of Excellence on Brain Aging NYU Langone Medical Center New York, NY 10016, USA Dr. Osorio[/caption] Ricardo S Osorio MD Center for Brain Health Department of Psychiatry Center of Excellence on Brain Aging NYU Langone Medical Center New York, NY 10016, USA  MedicalResearch.com: What is the background for this study? What are the main findings? Response: This was a study that was performed in a group of healthy normal elderly from the community that volunteered for studies on memory and aging. The main findings were that sleep apnea was very common, in almost all cases undiagnosed, and that it was associated with a longitudinal increase in amyloid burden which is considered one of the hallmark lesions of Alzheimer's disease
Author Interviews, JAMA, Obstructive Sleep Apnea, Sleep Disorders / 27.01.2017

MedicalResearch.com Interview with: [caption id="attachment_31527" align="alignleft" width="133"]Dr. Alex Krist, MD MPH Task Force member Associate Professor Fairfax Family Medicine Residency Co-director, Ambulatory Care Outcomes Research Network Virginia Commonwealth University Dr. Alex Krist[/caption] Dr. Alex Krist, MD MPH Task Force member Associate Professor Fairfax Family Medicine Residency Co-director, Ambulatory Care Outcomes Research Network Virginia Commonwealth University MedicalResearch.com: What is the background for this study? What are the main findings? Response: Obstructive sleep apnea (OSA) has been found to be associated with serious health conditions, including heart disease and diabetes. Additionally, OSA can cause excessive daytime sleepiness, which can significantly impact a person’s quality of life, increase involvement in motor vehicle crashes, and lead to an increased risk of death. Estimates show that OSA affected between 10 and 15% of the U.S. population in the 1990s, and rates may have increased over the past 20 years, so the Task Force wanted to examine the evidence on screening adults without symptoms or symptoms for obstructive sleep apnea.