Author Interviews, CMAJ, COVID -19 Coronavirus, Kidney Disease / 05.02.2021

MedicalResearch.com Interview with: Peter G. Blake MD, FRCPC, FRCPI,MSc MB Professor of Medicine in the Division of Nephrology Ontario Renal Network University of Western Ontario and London Health Sciences Centre London, Ontario MedicalResearch.com: What is the background for this study? What are the main findings? Response: The Covid-19 pandemic has been very difficult for people on dialysis with reports of high infection rates and high mortality. We prospectively collected data on SARS-CoV-2 infection every week from all renal programs in the province of Ontario, Canada from the start of the pandemic. Between March and August 2020, 187 people on dialysis, equivalent to 1.5% of all those in the province, were infected with the SARS-CoV-2 virus. Over 60% were hospitalized, 20% required ICU and the mortality rate was very high at over 28%. Risk factors for infection included center hemodialysis versus home dialysis, residing in long term care, black, south Asian and other non-white ethnicity, and low neighbourhood income. (more…)
Author Interviews, CMAJ, Orthopedics, Rheumatology, Surgical Research / 02.02.2021

MedicalResearch.com Interview with: Codie Primeau, MSc Physical Therapy Student & Ph.D. Candidate (Combined MPT/Ph.D.) Wolf Orthopaedic Biomechanics Lab, Fowler Kennedy Sport Medicine Clinic Western University London, ON, Canada MedicalResearch.com: What is the background for this study? Response: High tibial osteotomy (HTO) is a surgery for patients with varus alignment (bowed legs) and earlier-stage knee osteoarthritis. By correcting alignment, HTO shifts load to less diseased parts of the knee. One of the goals of HTO is to delay or even prevent the need for knee replacement surgery later. (more…)
Author Interviews, Cannabis, Depression, OBGYNE / 08.08.2019

MedicalResearch.com Interview with: Jamie A. Seabrook, Ph.D. Associate Professor, School of Food and Nutritional Sciences Brescia University College at Western University Adjunct Research Professor, Dept of Paediatrics, Western University Adjunct Associate Professor, Dept of Epidemiology & Biostatistics, Western University Scientist, Children's Health Research Institute Scientist, Lawson Health Research Institute MedicalResearch.com: What is the background for this study? What are the main findings? Response: Alcohol, tobacco, and cannabis are the most commonly used substances during pregnancy. High alcohol consumption has been linked with preterm birth, and tobacco and/or cannabis use is associated with low birth weight. Much of what we know about predictors of drug use during pregnancy comes from the United States and Australia, with limited studies in Canada. The objective of our study was therefore to assess the relative effects of socioeconomic, demographic, and mental health risk factors associated with drug use during pregnancy. Our retrospective cohort study consisted of 25,734 pregnant women from Southwestern Ontario. We found that maternal depression was the top risk factor associated with all three substances. Compared to women who were not depressed during their pregnancy, women who were depressed were 2.2 times more likely to use alcohol (95% CI: 1.6, 2.9), 1.7 times more likely to smoke tobacco (95% CI: 1.5, 2.0), and 2.6 times more likely to use cannabis (95% CI: 2.0, 3.4). (more…)