18 Jul High Dose Vitamin D No Advantage In Preventing Pediatric Viral Infections
MedicalResearch.com Interview with:
Dr. Maguire
Jonathon Maguire MD MSc FRCPC
Scientist, Li Ka Shing Knowledge Institute
Staff Pediatrician, Department of Pediatrics, St. Michael’s Hospital
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Vitamin D has been hypothesized as being protective of seasonal viral upper respiratory tract infections. In this randomized clinical trial, high dose wintertime vitamin D supplementation (2000 IU/day) was compared with standard-dose vitamin D supplementation (400 IU/day) among 703 children. The number of laboratory confirmed viral upper respiratory tract infections was not statistically different between groups.
MedicalResearch.com: What should clinicians and patients take away from your report?
Response: High dose wintertime vitamin D supplementation is unlikely to prevent viral upper respiratory tract infections relative to standard dose vitamin D supplementation in children.
MedicalResearch.com: What recommendations do you have for future research as a result of this study?
Response: Given that high dose vitamin D supplementation appears to provide no protective advantage over standard dose vitamin D supplementation in children, future research might investigate whether standard dose vitamin D offers protection from viral upper respiratory tract infections relative to placebo.
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Last Updated on July 18, 2017 by Marie Benz MD FAAD