25 Mar SIR24: MRI guided TULSA Study at 5 years Effective in Eliminating Prostate Cancer in Almost 80% of men with Fewer Sexual and Urinary Side Effects

MedicalResearch.com Interview with:

Dr. Raman

Steven S. Raman, M.D., FASR, FSIR
Professor of Radiology, Urology and Surgery
David Geffen School of Medicine
UCLA

MedicalResearch.com: What is the background for this study? Would you describe the TULSA technique?

Response: Prostate cancer is the most common solid organ cancer in men.  Currently whole gland ablation relies on surgery or radiation both of which have high rates of impotence and incontinence but also have up to a 30% rate of post therapy recurrence.

TULSA is a new minimally invasive technique to treat PCa under MRI guidance with both near continuous whole gland MRI imaging and MRI thermometry to make sure the extent of lethal heating over 55 degrees Celsius is known. 

MedicalResearch.com: What are the main findings?

Response:  MRI guided TULSA at 5 years was effective in eliminating PCa in almost 80% of men with much fewer sexual and urinary side effects.

MedicalResearch.com: What should readers take away from your report?

Response: MRI guided TULSA may provide an alternative to surgery and radiation for whole gland treatment of PCa with fewer side effects.

 MedicalResearch.com: What recommendations do you have for future research as a results of this study?

Response: Need a randomized trial with surgery (CAPTAIN) and radiation (TBD) as well a trial of TULSA for higher intermediate risk PCa  and TULSA vs Active Surveillance and focal therapy for intermediate risk PCa.

Citation: Abstract #135: Five-year outcomes after MRI-guided transurethral ultrasound ablation (TULSA) of localized prostate cancer. S. Raman, S. Arora, K. Macura, A. Oto, J. Futterer, T. Tirkes, D. Costa. Annual Scientific Meeting, March 23-28, 2024. This abstract can be found at sirmeeting.org.

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Last Updated on March 25, 2024 by Marie Benz MD FAAD