Computerized Clinical Decision Support Systems Can Reduce Rate of Venous Thromboembolism Interview with:
Zachary Borabm, Research fellow

Hansjörg Wyss Department of Plastic Surgery
NYU Langone Medical Center What is the background for this study? What are the main findings?

Response: Recent studies have shown that health care providers perform poorly in risk stratifying their patients for venous thromboembolism (VTE) which leads to inadequate VTE prophylaxis delivery, especially in surgical patients. Computerized Clinical Decision Support Systems (CCDSSs) are programs integrated into an electronic health record that have the power to aid health care providers. Using a meta-analysis study technique we were able to pool data from 11 studies, including 156,366 patients that either had CCDSSs intervention or routine care without CCDSSs.

Our main outcome measures were the rate of prophylaxis for VTE and the rate of actual VTE events. We found that CCDSSs increased the rate of VTE prophylaxis (odds ratio 2.35, p<0.001) and decreased the risk of VTE events (risk ratio 0.78, p<0.001). What should readers take away from your report?

Response: Readers should take away that CCDSSs are a powerful tool to provide the best care for patients and can definitely help reduce the incidence of VTE. What recommendations do you have for future research as a result of this study?

Response: We have limited our study to include only outcome measures for VTE prevention CCDSSs. These support systems can be broadened to improve care in many other areas of medicine. In the future we plan to conduct further research to assess the value of using a CCDSS for preoperative risk planning and enhancing the process of informed consent.

No Disclosures. Thank you for your contribution to the community.


Borab ZM, Lanni MA, Tecce MG, Pannucci CJ, Fischer JP. Use of Computerized Clinical Decision Support Systems to Prevent Venous Thromboembolism in Surgical PatientsA Systematic Review and Meta-analysis. JAMA Surg. Published online March 15, 2017. doi:10.1001/jamasurg.2017.0131

Note: Content is Not intended as medical advice. Please consult your health care provider regarding your specific medical condition and questions.

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Last Updated on March 23, 2017 by Marie Benz MD FAAD