Obstructive Sleep Apnea Common in Patients with Resistant Hypertension Interview with:
Mireia Dalmases Cleries, MD
Hospital Universitari Arnau de Vilanova and Santa Maria
Group of Translational Research in Respiratory Medicine
Lleida, Cataluña, Spain What is the background for this study?

Response: Obstructive sleep apnea has been associated with poor blood pressure control and resistant hypertension. Moreover, it has been described that its treatment with continuous positive pressure (CPAP) could be an effective means of controlling blood pressure in this population.

Nevertheless, studies assessing OSA prevalence, characteristics and association with blood pressure control in resistant hypertensive patients are limited and that’s the reason why we decided to perform this study. What are the main findings?

Response: Our study confirms the high prevalence of obstructive sleep apnea in resistant hypertensive participants, around 83%. Furthermore, it shows a dose-response association between OSA severity and BP measurements, especially in the nighttime. What should readers take away from your report?

Response: There is a high prevalence of obstructive sleep apnea in resistant hypertensive patients and the severity of obstructive sleep apnea impacts on blood pressure control, therefore it should be considered to screen obstructive sleep apnea in resistant hypertensive subjects. What recommendations do you have for future research as a result of this work?

Response: The results highlight the importance of identifying OSA in resistant hypertensive subjects, therefore the following step should be to evaluate the impact of treating obstructive sleep apnea with CPAP on blood pressure control and cardiovascular outcomes at the long-term. In fact, nowadays there is an ongoing project (SARAH project: Long-term Cardiovascular Outcomes in Patients With RH and OSA With or Without Treatment With CPAP) that will show light on these topic in the following years.

Nothing to disclosure


Prevalence, Characteristics and Association of Obstructive Sleep Apnea with Blood Pressure Control in Patients with Resistant Hypertension

Esther Sapiña-Beltrán ; Gerard Torres , Ivan Benitez , Ana Maria Fortuna-Gutiérrez ; Paola Ponte Márquez , Juan Fernando Masa ; Jaime Corral-Peñafiel ; Luciano F Drager , Mayara Cabrini , Miquel Félez , Susana Vázquez ,et al PubMed: 31514508


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Last Updated on September 13, 2019 by Marie Benz MD FAAD