12 Jul Co-infection with HPV and Chlamydia Can Be Asymptomatic and Lead to Infertility
MedicalResearch.com Interview with:
Dejan R. Nonato, MD, PhD
Institute of Tropical Pathology and Public Health
School of Medicine
Federal University of Goiás
Goiânia, GO, Brazil
MedicalResearch.com: What is the background for this study?
Response: Human papillomavirus (HPV) and Chlamydia trachomatis (CT) share the same route of sexual transmission and possess similar risk factors, indicating that co-infection may act synergistically in the induction of epithelial cell abnormalities.
MedicalResearch.com: What are the main findings?
Response: The prevalence of co-infection among our study population was of a magnitude that warrants attention by public health services. Adolescents and young women should be monitored for Chlamydia trachomatis infection and vaccinated against HPV. The association between cytological abnormalities and co-infection with HPV and CT indicates the potential synergistic role of these infections in carcinogenesis of the cervix.
MedicalResearch.com: What should readers take away from your report?
Response: Factors associated with HPV/CT confection. HPV/CT confection in adolescents and young women showed association with initiation of sexual activity and with risk for the detection of cytological abnormalities.
MedicalResearch.com: What recommendations do you have for future research as a result of this study?
Response: The co-infection with Chlamydia trachomatis that frequently occurs in an asymptomatic but chronic form can lead to an inability to become pregnant or an ectopic pregnancy, it can also be the cause of perinatal morbidity and mortality. The high prevalence of CT shown in the present co-infection study in young patients and the 90 million expected new cases worldwide reported by Kucinskiene et al (2006) indicate the imperative need to implement effective strategies to safeguard public health, such as population screening and the development and production of vaccines.
MedicalResearch.com: Thank you for your contribution to the MedicalResearch.com community.
Citation:
Prevalence and factors associated with co-infection of human papillomavirus and Chlamydia trachomatis in adolescents and young women
Nonato, Dejan R. et al.
American Journal of Obstetrics & Gynecology , Volume 0 , Issue 0 July 8 2016
DOI: http://dx.doi.org/10.1016/j.ajog.2016.07.003
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Last Updated on July 15, 2016 by Marie Benz MD FAAD