MedicalResearch.com Interview with:
Fumiaki Ikeno M.D.
Program Director (U.S.) Japan Biodesign
Medical Director/Research Associate
Experimental Interventional Laboratory
Division of Cardiology
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: We sought to determine whether the extent of coronary disease in terms of the number of lesions and their complexity in Type 2 Diabetes patients could predict major cardiovascular events, and hypothesized that revascularization would have greater effectiveness relative to medical therapy among patients with more number of lesions and higher complexity in coronary artery disease.
Coronary bypass surgery, catheter-based treatment, and medical therapy all had similar cardiovascular outcomes among patients with less complexity of coronary artery disease who had type 2 diabetes mellitus, stable ischemic heart disease, and no prior coronary revascularization. Among patients with mid or high complexity coronary artery disease, coronary revascularization with bypass surgery significantly reduced the rate of major cardiovascular events during 5 years of follow-up.
MedicalResearch.com: What should readers take away from your report?
Response: For the Type 2 Diabetes patients with the higher extent of coronary disease in terms of the number of lesions and their complexity, bypass surgery is considered to be the recommended treatment choice to achieve better outcome.
MedicalResearch.com: What recommendations do you have for future research as a result of this study?
Response: This study is one of sub-analysis of BARI2D trial which the study enrollment was started just before drug eluting stent had started to be used in US, but the current usage of Drug eluting stent is much higher, so the similar study with drug eluting stent era is interesting.
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