Early Study Demonstrates Airways Can Be Transplanted from Aortic Templates

MedicalResearch.com Interview with:
Emmanuel Martinod MD PhD
Assistance Publique–Hôpitaux de Paris, Hôpitaux Universitaires Paris Seine-Saint-Denis, Hôpital Avicenne, Chirurgie Thoracique et Vasculaire, Université Paris 13, Sorbonne Paris Cité, UFR Santé, Médecine et Biologie Humaine, Bobigny,
Université Paris Descartes, Fondation Alain Carpentier, Laboratoire de Recherche Bio-chirurgicale, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou
Paris, France 

MedicalResearch.com: What is the background for this exciting new technology and study? What are the main findings? 

Response: What is the background for this exciting new technology and study? What are the main findings?

Response:  The background is 10 years of research at laboratory followed by 10 years of academic clinical research.

We demonstrated the feasability of airway bioengeenring using stented aortic matrices for complex tracheal or bronchial reconstruction. 
MedicalResearch.com: What should readers take away from your report?

Response: The possibility of airway transplantation in patients with end-stage tracheal disease or proximal lung tumor in order to avoid pneumonectomy  

MedicalResearch.com: What recommendations do you have for future research as a result of this work?

Response: The next steps will be randomized trials for the evaluation of subgroups of diseaes requiring airway transplantation.

No disclosures 


Martinod E, Chouahnia K, Radu DM, et al. Feasibility of Bioengineered Tracheal and Bronchial Reconstruction Using Stented Aortic Matrices. JAMA. Published online May 20, 2018. doi:10.1001/jama.2018.4653

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Last Updated on May 21, 2018 by Marie Benz MD FAAD