Oral Anticoagulants Still Underused in AFib Patients

MedicalResearch.com Interview with:
Anna Gundlund, MD, PhD

Herlev-Gentofte Hospital, Department of Cardiology

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: Atrial fibrillation increases a person’s risk of ischemic strokes up to 5-fold. Oral anticoagulation therapy lowers this risk effectively (>60%) and is therefore recommended for patients with atrial fibrillation and at least 1-2 other risk factors for stroke.

Our study show, that oral anticoagulation therapy is still underused in patients with atrial fibrillation – even after a stroke event. In stroke survivors with atrial fibrillation, oral anticoagulation therapy were associated with better outcomes than no oral anticoagulation therapy. 

MedicalResearch.com: What should readers take away from your report?

Response: Oral anticoagulation therapy is effective (and safe) as secondary stroke prophylaxis in patients with atrial fibrillation.

MedicalResearch.com: What recommendations do you have for future research as a result of this work? 

Response: Treatment rates with oral anticoagulation therapy have increased over time and we should keep on being aware that this tendency continues.

No disclosures


Gundlund A, Xian Y, Peterson ED, et al. Prestroke and Poststroke Antithrombotic Therapy in Patients With Atrial FibrillationResults From a Nationwide CohortJAMA Network Open. 2018;1(1):e180171. doi:10.1001/jamanetworkopen.2018.0171

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Last Updated on May 19, 2018 by Marie Benz MD FAAD