MedicalResearch.com Interview with:
Madelein Hoogwegt, MSc
Promovenda
Center of Research on Psychology in Somatic diseases (CoRPS)
Department of Medical and Clinical Psychology
Kamer P711 Tilburg University 5000 LE Tilburg
MedicalResearch.com: What are the main findings of the study?
Answer: The main finding was that we found a significant relation between positive affect and mortality, and that exercise explained this relationship. With respect to the second outcome, hospitalization, we found a significant relation between positive affect and hospitalization, a significant relation between positive affect and hospitalization, but exercise did not mediate this relationship.
MedicalResearch.com Interview with:
Thomas P. J. Solomon, Ph.D.
Associate Professor of Biomedical Sciences
Department of Biomedical Sciences | Cellular & Metabolic Research Section
Panum Institute 4.5 | University of Copenhagen | Blegdamsvej 3B | 2200 Copenhagen N | Denmark
MedicalResearch.com: What are the main findings of the study?
Dr. Solomon: The main findings were that when impaired glucose tolerant and type 2 diabetic subjects underwent 3-4 months of regular aerobic exercise training, although the majority of subjects (86-90%) increased increased VO2max, lost weight, and increased insulin sensitivity, only around two-thirds of subjects improved glycemic control (HbA1c, fasting glucose, and 2-hour OGTT glucose). The novel finding was that the changes in glycemic control were congruent with changes in oral glucose-stimulated insulin secretion (GSIS). We also found that exercise training-induced changes in glycemic control were related to changes in GSIS (P0.05), but not insulin sensitivity. Furthermore, we found that training-induced improvements in glycemic control were largest in subjects with greater pre-training GSIS, i.e. in subjects with greatest beta-cell function. And, we noted that high pre-training hyperglycemia blunted exercise-induced improvements in beta-cell compensation for insulin resistance.
Michelle N. McDonnell, PhD
Division of Health Sciences
International Centre for Allied Health Evidence
University of South Australia
Adelaide, SA 5001 Australia.
MedicalResearch.com: What are the main findings of the study?
Dr. McDonnell: In this study, we asked people how many times a week they engaged in intense physical activity, enough to work up a sweat. People responded that they were physically active 0, 1-3 or 4 or more times a week. When we followed up these people for several years, those who did not do any vigorous exercise were 20% more likely to have a stroke, compared to those who exercised four or more times a week. However, when we adjusted these results for other risk factors, this attenuated the effect down to 14% which was not statistically significant. We also noticed that people who exercised four or more times a week had less hypertension (high blood pressure), were less likely to be obese and less likely to have diabetes. Each of these things on their own reduces your risk of stroke, so when we adjust for that the association between physical activity and stroke is weaker (20% to 14%). So physical activity seems to have an effect on stroke risk by improving these other risk factors.
MedicalResearch.com eInterview with
Martin Sénéchal, Ph.D.
Postdoctoral Researcher
The Manitoba Institute of Child Health
University of Manitoba
511E- 715 McDermot Ave Winnipeg, Manitoba
MedicalResearch.com: What are the main findings of the study?
Answer: The main finding of this study is that reducing central adiposity and increasing fitness in men and women with Type 2 diabetes are key components for successfully improving glycemic control.
A secondary finding of the study is that improvement in both central adiposity (reduction) and fitness (increasing) simultaneously; increase the likelihood of reducing HbA1c, one of the most widely used indicators of glucose control, and/or Type 2 diabetes medications.
ROCHESTER, Minn. - Any exercise that gets the heart pumping may reduce the risk of dementia and slow the condition's progression once it starts, reported a Mayo Clinic study published this month in Mayo Clinic Proceedings. Researchers examined the role of aerobic exercise in preserving cognitive abilities and concluded that...