22 Jun MRI Brain Scans Can Predict Disruption of Blood-Brain Barrier in Stroke Patients

MedicalResearch.com Interview with:

Dr. Richard Leigh

Dr. Richard Leigh MD
Neuro Vascular Brain Imaging Unit
National Institute of Neurological Disorders and Stroke
National Institutes of Health, Bethesda, MD

MedicalResearch.com: What is the background for this study? What are the main findings?

Response: Patients who suffer an ischemic stroke have limited treatment options. One of the reasons for this is that our treatments can sometimes make the stroke worse by transforming the ischemic stroke into a hemorrhagic stroke. In our study we identified a new piece of information that we can extract from the patient’s MRI scan that informs us on the risk of having a hemorrhage.

MedicalResearch.com: What should readers take away from your report?

Response: These findings suggest that we may be able to expand the number of stroke patients who can be safely treated.

MedicalResearch.com: What recommendations do you have for future research as a result of this study?

Response: Future studies will need to determine the clinical context in which this new information will be most useful.

MedicalResearch.com: Thank you for your contribution to the MedicalResearch.com community.

Citation:

Pretreatment blood–brain barrier disruption and post-endovascular intracranial hemorrhage
Richard Leigh, MD,Søren Christensen, PhD,Bruce C.V. Campbell, MBBS, PhD,
Michael P. Marks, MD,Gregory W. Albers, MD,Maarten G. Lansberg, MD, PhD;
For the DEFUSE 2 Investigators

Published online before print June 17, 2016, doi: http://dx.doi.org/10.1212/WNL.0000000000002862Neurology 10.1212/WNL.0000000000002862

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Last Updated on June 22, 2016 by Marie Benz MD FAAD