09 Sep Adolescent Inflammation Associated with Premature Mortality
MedicalResearch.com Interview with:
Dr. Elizabeth D. Kantor
Elizabeth D. Kantor, PhD MPH
Department of Epidemiology and Biostatistics
Memorial Sloan Kettering Cancer Center
NY, NY
MedicalResearch.com: What is the background for this study?
Response: There has been recent interest in understanding how exposures in childhood and adolescence relate to later-life health outcomes.
Although inflammation is thought to play a role in the etiology of various diseases, little is known about the long-term implications of inflammation in early life. We therefore sought to evaluate how erythrocyte sedimentation rate (ESR), a marker of inflammation, measured among ostensibly healthy men in late adolescence, relates to subsequent cause-specific mortality.
We found that men with high inflammation in late adolescence experienced increased mortality due to cancer and cardiovascular disease.
MedicalResearch.com: What are the main findings?
Response: Here, we observed that high inflammation in late adolescence was associated with increased premature mortality due to cancer and cardiovascular disease. As this study was conducted among ostensibly healthy men, our results suggest that this marker of inflammation is capturing something beyond health conditions manifested in adolescence.
MedicalResearch.com: What recommendations do you have for future research as a result of this work?
Response: Of course, this is an observational study and there are limitations to consider, but these results are definitely interesting and suggest a need for further research to understand the role of early life inflammation in later-life outcomes.
Citation:
JOIN OUR EMAIL LIST
[mailpoet_form id="5"]We respect your privacy and will never share your details.
Last Modified: [last-modified]
The information on MedicalResearch.com is provided for educational purposes only, and is in no way intended to diagnose, cure, or treat any medical or other condition. Always seek the advice of your physician or other qualified health and ask your doctor any questions you may have regarding a medical condition. In addition to all other limitations and disclaimers in this agreement, service provider and its third party providers disclaim any liability or loss in connection with the content provided on this website.
Last Updated on September 9, 2019 by Marie Benz MD FAAD