CBD Tag

08 Jul

Posted at 10:35h in Cannabis, Pain Research

Cannabis/CBD Notice: Cannabis products are not FDA monitored or approved. Discuss your use of medicinal cannabis or CBD products with your healthcare provider before use. Dosing is variable and products may interfere with other medications, stimulants and alcohol. Do not use cannabis or CBD products if you are pregnant, nursing, or may become pregnant. Do not use cannabis products when driving or operating difficult or dangerous machinery. Keep out of reach of children. Children and pets should not be exposed to cannabis or CBD products.

Chronic pain continues to be a complex challenge in modern medicine, driving significant research into non-opioid alternatives. Among the most closely monitored developments is the clinical application of cannabidiol (CBD). In Australia, the intersection of evolving clinical efficacy data and highly regulated patient access frameworks presents a fascinating case study in modern pain management.

For broader context on why medicinal cannabis is attracting clinical attention globally, see this overview of five reasons it is used for pain management, as well as this deeper look at how cannabinoids interact with the endocannabinoid system.

[caption id="attachment_74821" align="aligncenter" width="500"]evolving-Cannabidiol-australia-pexels Photo by Kindel Media[/caption]

29 Jun

Posted at 11:35h in Cannabis, Sleep Disorders

Cannabis / CBD Notice: CBD and cannabidiol-based products are not approved by the U.S. Food and Drug Administration to diagnose, treat, cure, or prevent any disease or medical condition, including sleep disorders. The legal status of CBD products varies by state and country. These products may interact with prescription medications. Always consult a qualified healthcare provider before using any CBD or cannabis-derived product, particularly if you are pregnant, nursing, taking medications, or have an underlying health condition. MedicalResearch.com and Eminent Domains Inc. do not warrant or endorse any CBD product, brand, or supplier referenced in this post. Cannabis products should not be used if you are pregnant, nursing or may become pregnant or while driving or performing potentially dangerous tasks.  Keep out of reach of children and pets.

The appeal of CBD gummies for sleep is easy to understand. Something natural, no prescription required, no morning grogginess or addiction risk associated with conventional sleep aids. But the gap between what CBD gummies can realistically do and what the marketing often implies is wider than most first-time buyers realize. Getting clear on the science, the product standards, and the practical approach before you start will save you the frustration of buying something that does not match your situation.

1. CBD Works on Sleep Differently Than You Might Expect

CBD does not make you sleepy the way antihistamines or sedatives do. It does not switch off your brain. What research suggests it may do is reduce the anxiety and physiological arousal that prevents sleep from coming. A review published in PubMed by the National Library of Medicine found that CBD demonstrated anxiolytic effects in clinical research, with participants reporting reduced anxiety without impaired alertness. Since anxiety and an overactive stress response are among the most common drivers of poor sleep onset, the mechanism makes clinical sense even if the evidence base is still developing. What this means practically: CBD gummies for sleep tend to work best for people whose sleep problem involves difficulty switching off mentally rather than a primary sleep disorder. If you lie awake with a racing mind, CBD is more likely to help than if you fall asleep easily but wake repeatedly at 3am. [caption id="attachment_74582" align="aligncenter" width="500"]gummies for sleep pexels image Pexels image[/caption]

21 Jun

Posted at 21:40h in Cannabis

Cannabis Notice: Cannabis laws and regulations vary by country, state, and territory. Cannabis use is intended for adults only and is illegal in many jurisdictions. This article is for educational purposes only and does not constitute medical advice. Cannabis products discussed here are not endorsed by MedicalResearch.com or Eminent Domains Inc. The effects of cannabis vary by individual, and some people may experience adverse reactions. Always consult a qualified healthcare provider before using cannabis, particularly if you have a medical condition, are pregnant or breastfeeding, or are taking prescription medications. Do not use cannabis and drive or operate heavy machinery. Keep cannabis products out of reach of children and pets.

Understanding-Cannabis-Types-and-Their-Differences

Cannabis is a plant that has gained a lot of attention in recent years. You might have heard friends or adults talk about it, but do you really understand what it is? Cannabis comes in many different types, each with its own unique effects and uses. Learning about these cannabis types can help you understand why people use them and how they can affect our bodies and minds.

What Is Cannabis?

Cannabis is a flowering plant that has been used for thousands of years. It contains special compounds called cannabinoids, which can affect the human body in various ways. Two of the most well-known cannabinoids are THC (tetrahydrocannabinol) and CBD (cannabidiol). THC is the compound that produces the feeling of being "high," while CBD is known for its calming effects without producing intoxication.

If you're interested in learning more about cannabis and possibly trying it out, you can visit https://gooddayfarmdispensary.com/dispensaries/ for information about local dispensaries and the various options they offer. Knowledge is key to making informed choices for your personal experience.

12 Jun

Posted at 21:16h in Author Interviews, Cancer Research, Cannabis

Editor's Note: Cannabis laws and regulations vary by country, state, and territory. This interview is for educational purposes only. Cannabis products discussed here are not endorsed by MedicalResearch.com. Patients should consult their oncologist or healthcare provider before using any cannabis or cannabinoid product, particularly during cancer treatment. Cannabis products should not be used while driving, by children, if pregnant, nursing or planning to become pregnant or mixed with other substances that can affect cognition. Cannabis products may also be contraindicated in other medical conditions or situations.

cannabis-and-cancer-posterMedicalResearch.com Interview with: Raphael E. Cuomo, PhD Associate Professor University of California, San Diego Developer and Host, Cannabis and Cancer (Apple TV Documentary)  
MedicalResearch.com: What is the background for this documentary? What are the primary components of cannabis plants? Response: I created Cannabis and Cancer because cannabis is now widely discussed by patients, clinicians, policymakers, and the general public, but there is still a lot of confusion about what the science actually says. Much of the public conversation treats cannabis as either broadly harmful or broadly beneficial. The reality is more complex. The documentary is meant to separate questions that are often conflated: whether cannabis exposure may influence the risk of developing cancer, whether cannabis use may affect cancer treatment or symptoms, and whether it may influence survival after a cancer diagnosis. These are very different scientific questions, and each one requires a different type of evidence. Cannabis plants contain many biologically active compounds. The most widely discussed are cannabinoids, especially THC and CBD. THC is the main intoxicating compound and is responsible for many of the psychoactive effects. CBD is not intoxicating in the same way, but it still has biological effects. Cannabis also contains other cannabinoids, terpenes, flavonoids, and plant compounds that may influence how different products affect the body.

08 May

Posted at 10:51h in Cannabis
[caption id="attachment_73613" align="aligncenter" width="500"]therapeutic-uses-cannabis.jpg Pexels[/caption]

Please note: Cannabis and cannabidiol (CBD) products are generally not FDA tested or approved for all conditions referenced in this article. Cannabis and CBD products can interfere with medications including blood pressure medications and anticoagulants. Do not use cannabis products if pregnant, nursing or planning to become pregnant. Do not delay seeking medical attention for medical concerns by using cannabis or CBD products without medical advice. Cannabis products should not be used while driving or operating machinery. Statements and product contents have not been independently confirmed by MedicalResearch.com or Eminent Domains Inc. Please discuss any and all cannabis or CBD use with your health care provider before beginning any such regimen.

The landscape of chronic condition management has undergone a significant transformation over the past decade. For years, the medical community relied heavily on isolated symptom treatments and traditional pharmacological interventions to manage complex ailments. Patients suffering from long-term conditions like neuropathy, chronic inflammation, or severe anxiety frequently found themselves cycling through various medications with limited success and significant side effects. These recurring challenges have prompted healthcare professionals to rethink standard protocols. The latest clinical evidence supports a multidimensional approach to chronic pain that incorporates alternative and complementary therapies, reflecting a broader shift away from conventional, single-track treatments. As recent insights into pain management demonstrate, invasive procedures and heavy medications are no longer the default first-line defense. Instead, clinicians are increasingly advocating for whole-person care that values patient lifestyle strategies, psychological support, and alternative therapeutics. Among these emerging alternatives, cannabidiol has garnered substantial attention from the global medical and academic communities as a viable option for those who have exhausted standard therapies.

27 Apr

Posted at 19:19h in Cannabis, Medical Equipment
[caption id="attachment_73444" align="aligncenter" width="500"]Protecting Cannabinoid Integrity Source: IMAGE[/caption]

Editor's note: Cannabis and THCA/Hemp CBD products should have an active ingredient list on the container and a Certificate of Analysis (COA). Discuss your use of THC, cannabis, or CBD products with your health care provider. Dosing of cannabis products is variable, especially since they are not FDA regulated. Cannabis/CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use cannabis products including edibles, drinks, and CBD if you are pregnant, nursing, or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products.

Whereas logistics professionals are more likely to concentrate on the purity and quality of laboratory extractions or cultivations, one of the most unstable parts of the medicinal substance's route to delivery — the final mile — may sometimes be neglected. The cannabis industry has turned to a pharmaceutical approach in 2026 to safeguard the chemical composition of the plant from exposure to damaging effects before reaching the end user.

The Science of Thermal Degradation and Molecular Shifts

The main challenge is the heat issue, which is considered the major cause of irregularity among chemicals. Research results from the beginning of 2026 indicate that different temperatures during transportation can affect the composition of cannabis within three hours by 15%.

25 Apr

Posted at 17:31h in Cannabis, Mental Health Research
[caption id="attachment_73388" align="aligncenter" width="500"]cbd-affecting-anxiety-differently.png SOURCE: IMAGE[/caption]

Editor's note: Cannabis and THCA/Hemp CBD products should have an active ingredient list on the container and a Certificate of Analysis (COA). Discuss your use of THC, cannabis, or CBD products with your health care provider. Dosing of cannabis products is variable, especially since they are not FDA regulated. Cannabis/CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use cannabis products including edibles, drinks, and CBD if you are pregnant, nursing, or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products.

A question that comes up constantly in cannabis research is one that patients have been asking for years: why does CBD ease anxiety in one person and make another feel worse? For a long time, the honest answer was that nobody fully knew. A landmark study out of McGill University changedthat, and the findings reveal something that most consumer guides on CBD have never properly explained.

The answer is not about product quality, dosage form, or brand. It comes down to how cannabis interacts with serotonin — and specifically why that interaction is not the same at every dose.

06 Mar

Posted at 20:47h in Author Interviews, Cannabis, Hepatitis - Liver Disease
Editor’ note:  Cannabis and THCA/HEMP CBD products should have an active ingredient list on the container and have a Certificate of Analysis (COA). Discuss your use of THC, Cannabis or CBD products with your health care provider.  Dosing of Cannabis products is variable, especially since they are not FDA regulated. Cannabis/CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles, drinks and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. MedicalResearch.com Interview with: Prof. Joseph (Yossi) Tam, DMD, PhD School of Pharmacy, Institute for Drug Research The Hebrew University of Jerusalem The Harvey M. Krueger Family Center for Nanoscience and Nanotechnology Jerusalem, IsraelProf. Joseph (Yossi) Tam, DMD, PhDSchool of Pharmacy, Institute for Drug Research The Hebrew University of Jerusalem The Harvey M. Krueger Family Center for Nanoscience and Nanotechnology Jerusalem, Israel With colleagues Dr. Liad Hinden, the PhD student Radka Kočvarová, and the Tam’s team at the School of Pharmacy at the Faculty of Medicine of the Hebrew University of Jerusalem.   MedicalResearch.com: What is the background for this study? Would you describe the condition of Metabolic dysfunction-associated steatotic liver disease (MASLD)? What causes it? Whom does it affect? Response: MASLD, formerly known as nonalcoholic fatty liver disease (NAFLD), is the most common chronic liver disorder worldwide. It develops when fat accumulates excessively in liver cells, commonly in people with obesity, insulin resistance, high cholesterol, or diabetes. Over time, this condition can progress to inflammation, fibrosis, or cirrhosis. Despite its growing prevalence, effective pharmacological therapies remain limited, leaving a substantial unmet clinical need.

21 Aug

Posted at 12:05h in Cannabis
Editor’ note:  Discuss your use of THC, Cannabis or CBD products with your health care provider.  Cannabis/CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. [caption id="attachment_70363" align="aligncenter" width="500"]bridge-between-medicine-cannabis Photo by MART PRODUCTION[/caption] The landscape of medical cannabis research is evolving rapidly, with new clinical studies emerging monthly that challenge long-held assumptions about cannabinoid therapy. As healthcare professionals navigate this complex field, the need for evidence-based information has never been more critical. Recent research developments are beginning to provide the scientific foundation that both patients and practitioners have been seeking. Current State of Clinical Research Medical cannabis research has accelerated significantly in recent years, with over 300 peer-reviewed studies published in 2024 alone. Key areas of investigation include chronic pain management, epilepsy treatment, cancer-related symptoms, and neurological disorders. The National Institutes of Health has increased funding for cannabinoid research by 40% since 2022, reflecting growing institutional recognition of therapeutic potential. Clinical trials are now examining specific cannabinoid ratios and their effects on various conditions. Research teams at major medical centers are particularly focused on understanding how different compounds interact with the endocannabinoid system and influence therapeutic outcomes.

30 Jul

Posted at 13:44h in Author Interviews, Cannabis
As cannabis use becomes increasingly mainstream, many individuals are seeking healthier ways to consume it. While smoking remains the most traditional method, concerns about respiratory health and long-term effects have prompted users to explore alternatives. This article delves into the health implications of smoking, vaping, and other delivery methods, providing an evidence-based comparison to help consumers make informed decisions.

Understanding the Risks of Smoking Cannabis

Smoking cannabis involves combusting the plant material, which produces smoke containing not only cannabinoids like THC and CBD but also a variety of harmful byproducts. These include tar, carbon monoxide, and carcinogenic compounds similar to those found in tobacco smoke. Research indicates that regular cannabis smoking can lead to respiratory issues such as chronic bronchitis, coughing, and phlegm production. While cannabis smoke contains fewer carcinogens than tobacco smoke, it still poses risks to lung health. However, unlike tobacco, cannabis smoking has not been definitively linked to lung cancer, though the data remains inconclusive due to limited long-term studies. One major concern is the temperature at which cannabis is combusted, typically around 600–900°C, which generates numerous toxic compounds. Additionally, smoking delivers cannabinoids rapidly but can irritate the respiratory tract, making it less suitable for those with pre-existing lung conditions.

26 May

Posted at 20:09h in Cannabis
Discuss your use of Cannabis or CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. Cannabis/CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. [caption id="attachment_68779" align="aligncenter" width="320"]cbd-purchase-cannabis Photo by Binoid CBD[/caption] For consumers looking for natural substitutes, the growing industry for CBD (cannabidiol) products has presented a world of wellness options. Accessing a large range of CBD oils and topicals has been easier due to the simplicity of online buying. However, consumers have to act to guarantee that the CBD products they purchase online are safe, premium, and powerful. Negotiating the huge digital market requires both a discriminating eye and a proactive strategy. This ultimate guide will offer basic advice and a methodical approach to enable customers to make wise choices when shopping for CBD products online. Prioritize transparency Transparency, more especially, by confirming the presence of thorough third-party lab testing, should be the most important advice for safe and wise CBD purchases online. Reputable CBD brands will provide access to thorough lab results by verifying the strength, purity, and safety of their goods. When considering CBD Products For Sale Online, confirm the right dosage of CBD and other cannabinoids.

03 May

Posted at 10:46h in ADHD
[caption id="attachment_68329" align="aligncenter" width="500"]adhd-cbd-adults Photo by Tara Winstead:[/caption] Cognitive behavioral therapy for ADHD offers effective strategies for managing attention and organizational challenges. This therapeutic approach helps people develop practical skills while addressing thought patterns that affect daily functioning. Understanding how CBT works specifically for ADHD can help people make informed decisions about their treatment options. The combination of behavioral changes and thought pattern awareness creates opportunities for lasting improvement in daily life.

Understanding the Basics

How CBT Works for ADHD

Cognitive-behavioral therapy for ADHD focuses on changing both thoughts and behaviors that interfere with daily life. This approach recognizes that ADHD affects more than just attention - it influences how people think about themselves and their abilities. The therapy helps develop new perspectives while building practical skills. Regular practice of these techniques leads to better management of ADHD symptoms and improved daily functioning.

13 Feb

Posted at 14:07h in Cannabis, Pain Research
Editor’ note:  Cannabis and THCA/HEMP CBD products should have an active ingredient list on the container and have a Certificate of Analysis (COA). Discuss your use of CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. [caption id="attachment_66542" align="aligncenter" width="500"]medical-cannabis-for-pain Photo by Michael Fischer on Pexels[/caption] Medicinal cannabis is a revolutionary approach to pain management, particularly in patients where conventional medications fail to offer them adequate relief or create intolerable side effects. With ongoing research on cannabis and its medicinal properties, its effectiveness for pain relief has become more convincing. Here are some reasons why medicinal cannabis has risen in popularity in pain management.

Natural Pain Relief Without Risks from Opioids

Many countries have been grappling with an opioid crisis, which has motivated patients to seek cannabis as a much safer alternative. Medicinal cannabis minimizes the risks of addiction associated with opioids due to misuse and gives little risk of an overdose. To obtain medicinal cannabis legally, there are options like medical marijuana cards you can obtain from providers such as Leafy Doc Mississippi. Regarding how cannabis works in terms of pain relief, cannabinoids like THC bind to receptors in the brain and the immune system, modulating the experience of pain. The endocannabinoid system engages with trauma states mainly on account of pain, mood regulation, and inflammation. However, for long-term relief, medicinal cannabis is viewed as a considerably safer alternative compared to opioids.

26 Jan

Posted at 16:49h in Cannabis
Editor’ note:  Cannabis and THCA/HEMP CBD products should have an active ingredient list on the container and have a Certificate of Analysis (COA). Discuss your use of CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be absorbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. potential-benefits-cannabis.png CBD and cannabis have been at the center of much talk about their therapeutic potential in recent years. As the benefits of these natural compounds become unveiled through more research, more individuals embrace them as a natural remedy for various health conditions. Once shrouded with different misconceptions, the medical community is exploring CBD and cannabis because of their potential effects on the body and mind. This article discusses the science behind these compounds, highlighting potential advantages while considering the role they can play in promoting health and well-being.

15 Jan

Posted at 00:59h in Author Interviews, Cannabis
MedicalResearch.com Interview with: Vishal A Shetty, MS, PhD Candidate Center for Pharmacy and Innovation Outcomes, Geisinger University of Massachusetts AmherstVishal A Shetty, MS, PhD Candidate Center for Pharmacy and Innovation Outcomes, Geisinger University of Massachusetts Amherst MedicalResearch.com: What is the background for this study? Response: With more U.S. states moving toward the legalization of medical and recreational cannabis, recent studies have explored electronic health record (EHR) documentation to understand the nature of cannabis use among patient populations. However, these efforts have not been extended to patient portal messaging, which allows patients to describe health-related behaviors in ways that may not be sufficiently captured in standard EHR documentation. The primary objective of this study was to identify patient and provider secure messages that discussed cannabis and contextualize these discussions over periods prior to and after its legalization for medical purposes in Pennsylvania.

02 Dec

Posted at 08:22h in Cannabis, Pain Research
Editor’ note:  Cannabis and THCA/HEMP CBD products should have an active ingredient list on the container and have a Certificate of Analysis (COA). Discuss your use of CBD products with your health care provider.  Dosing of CBD is variable, especially since it is not FDA regulated. CBD may interfere with other medications and should not be used in individuals with certain health conditions, including liver issues. CBD skin care products can be aborbed through the skin and have similar effects. Do not use Cannabis products including edibles and CBD if you are pregnant, nursing or may become pregnant. Do not use cannabis products if driving or operating difficult or dangerous machinery. Children should not be exposed to cannabis or CBD products. [caption id="attachment_65190" align="aligncenter" width="500"]cannabis-pain Photo by Michael Fischer on Pexels[/caption] Medicinal cannabis is a revolutionary approach to pain management, particularly in patients where conventional medications fail to offer them adequate relief or create intolerable side effects. With ongoing research on cannabis and its medicinal properties, its effectiveness for pain relief has become more convincing. Here are some reasons why medicinal cannabis has risen in popularity in pain management.

Natural Pain Relief Without Risks from Opioids

Many countries have been grappling with an opioid crisis, which has motivated patients to seek cannabis as a much safer alternative. Medicinal cannabis minimizes the risks of addiction associated with opioids due to misuse and gives no risks of an overdose. To obtain medicinal cannabis legally, there are options like medical marijuana cards you can obtain from providers such as Leafy Doc Mississippi. Regarding how cannabis works in terms of pain relief, cannabinoids like THC bind to receptors in the brain and the immune system, modulating the experience of pain. The endocannabinoid system engages with trauma states mainly on account of pain, mood regulation, and inflammation. However, for long-term relief, medicinal cannabis is viewed as a considerably safer alternative compared to opioids.

07 Oct

Posted at 12:08h in Cannabis
[caption id="attachment_63722" align="aligncenter" width="500"]https://www.freepik.com/free-photo/cbd-oil-dropper-arrangement_15576528.htm#fromView=search&page=1&position=51&uuid=2322f3cd-dbf2-4803-adcf-09d3838b15fc Source[/caption]   In recent years, Florida has seen significant growth in the medical cannabis industry. This expansion has transformed healthcare options for patients across the state. Medical cannabis is now being accepted as a viable treatment for various medical conditions. It is providing new alternatives for those seeking relief from chronic pain, anxiety, and other health issues. With the increasing acceptance of cannabis, Florida dispensaries are making a difference in people's lives. These establishments are vital in enhancing patient care and offering personalized treatment options. A Florida dispensary focuses on promoting wellness through education and support. They contribute significantly to Florida's healthcare landscape, helping improve patient outcomes. 

07 Oct

Posted at 11:30h in Cannabis
  [caption id="attachment_63791" align="aligncenter" width="500"]CBD oil.png Photo from Freepik[/caption] The search for natural pain relief and wellness solutions has led many to rediscover the therapeutic power of CBD. When combined with massage therapy, CBD oils may offer a powerful synergy, potentially promoting relaxation, reducing inflammation, and alleviating chronic discomfort. This blend of science-backed benefits and holistic care transforms a simple massage into a deeply rejuvenating experience. As more people seek non-invasive alternatives for their health, CBD-infused massage therapy may help  provide an effective option for mind and body healing.

12 Sep

Posted at 09:17h in Cannabis
Editor's note: Please remember the products described below are not FDA tested or approved. The use of edibles can cause unpredictable and potentially serious side effects, including addiction. No cannabinoids in any form should be used while pregnant, nursing or planning to become pregnant. Be sure to avoid driving or any activity which requires mental alertness. It is also important to recognized that these products are not legal in all jurisdictions.  As more people explore the benefits of cannabis, THC edibles have become an increasingly popular way to experience its effects. For beginners, however, edibles can be a little intimidating due to their differences from smoking or vaping cannabis. This guide aims to break down what you need to know about THC edibles, from how they work in the body to tips on choosing safe and reputable products.

How THC Edibles Differ from Smoking or Vaping

When you consume THC through smoking or vaping, it enters your bloodstream quickly via your lungs, leading to effects within minutes. This rapid onset allows users to better control their dose and understand their tolerance more quickly. However, smoking or vaping comes with potential risks to the respiratory system, especially with long-term use. THC edibles, on the other hand, take a different route through the body. When you eat an edible, the THC is absorbed through your digestive system and processed by the liver, which converts it into 11-Hydroxy-THC. This metabolite is known to produce stronger and longer-lasting effects compared to the THC that enters the bloodstream through smoking. However, it also takes longer for these effects to kick in—usually between 30 minutes to two hours. For this reason, beginners should exercise patience and avoid taking additional doses too soon, as it’s easy to overconsume without realizing it.

05 Aug

Posted at 20:01h in Addiction, Author Interviews, Cannabis
MedicalResearch.com Interview with: [caption id="attachment_62745" align="alignleft" width="130"] Luke Cavanah[/caption] Luke Cavanah, BS Department of Medical Education Geisinger Commonwealth School of Medicine Scranton, PA 18509 MedicalResearch.com: What is the background for this study? Response: Amphetamine, lisdexamfetamine, and methylphenidate, are first-line treatments for attention-deficit hyperactivity disorder (ADHD) and are classified as Schedule II stimulants due to their risk of addiction. (1–3) There has been high and increasing use and misuse of these medications with inadequate explanation. (4)  Since chronic cannabis use can result in similar cognitive effects as ADHD 5–7, we wondered if more stimulants were prescribed for what appeared to be ADHD but was a consequence of chronic cannabis use. In other words, has the legalization of cannabis contributed to this inadequately explained increase in stimulant use? A recent study by our lab group that looked at the slopes of stimulant distribution rates over time -- before and after medical cannabis legalization -- did not support this.(8) Given the prevalence and increasing legalization of recreational cannabis, we wanted to determine how slopes of stimulant distribution rates compared before and after recreational cannabis legalization.

08 Mar

Posted at 21:51h in Author Interviews, Cannabis, Pharmacology, Tobacco Research
MedicalResearch.com Interview with: [caption id="attachment_60149" align="alignleft" width="150"]Philip Lazarus, PhDBoeing Distinguished Professor, Pharmaceutical Sciences Professor, Dept of Pharmaceutical Sciences College of Pharmacy and Pharmaceutical Sciences Washington State University Spokane, WA 99210 Dr. Lazarus[/caption] Philip Lazarus, PhD Boeing Distinguished Professor, Pharmaceutical Sciences Professor, Dept of Pharmaceutical Sciences College of Pharmacy and Pharmaceutical Sciences Washington State University Spokane, WA 99210   MedicalResearch.com: What is the background for this study? Response: Smoking and tobacco use remains a major health issue. Smokers use cigarette over the course of the day because the levels of nicotine, the addictive agent in cigarettes and other forms of tobacco, dimmish with time in the bloodstream due to the breakdown of nicotine by enzymes in the body. By inhibiting the breakdown of nicotine in smokers, one would expect that the levels of nicotine would remain higher after smoking a single cigarette, and that these individuals may not require lighting up another cigarette so quickly, reducing the number of cigarettes smoked over the course of a day. This could have a profound effect on reducing the overall harm incurred from smoking or from using other forms of tobacco. In a single previous study, smokers who used a CBD inhaler exhibited a 40% reduction in cigarette use. In addition, while cannabis users are often smokers, previous studies have indicated that they smoke less cigarettes than non-cannabis-using cigarette smokers. In previous studies published in 2021, we found that major cannabinoids present in cannabis like THC and CBD inhibit major metabolizing enzymes in our body, including several that are important in drug metabolism. We hypothesized that CBD and its major active metabolite, 7-hydroxy (OH)-CBD, may also be inhibiting one or more of the enzymes important in the metabolism (or breakdown) of nicotine.

19 Mar

Posted at 16:36h in Annals Internal Medicine, Author Interviews, Cannabis, Yale
MedicalResearch.com Interview with: [caption id="attachment_53477" align="alignleft" width="200"]Joshua D. Wallach, MS, PhD Assistant Professor of Epidemiology (Environmental Health Sciences) Yale School of Public Health New Haven, CT  Dr. Wallach[/caption] Joshua D. Wallach, MS, PhD Assistant Professor of Epidemiology (Environmental Health Sciences) Yale School of Public Health New Haven, CT MedicalResearch.com: What is the background for this study? Response: Over the past few years, there has been growing interest in the potential health benefits of cannabidiol (CBD), a chemical compound in cannabis. Although only one CBD-derived prescription drug has been approved by the US Food and Drug Administration (FDA) for the treatment of epilepsy, I recently started seeing products containing CBD advertised and sold across the US (e.g. CBD in foods, beverages, dietary supplements, and cosmetics). I noticed that many of these products were being marketed with unproven claims to prevent, cure, and treat various conditions, and became interested in learning more about the research supporting the use of CBD, the potential for misleading claims, and impact that the CBD-industry may be having on research that is being generated and disseminated to the public. Research funding sources and other author conflicts of interests (e.g. consulting fees, honoraria, travel expenses) can influence the way that research is designed, conducted, and reported. Previous studies have consistently demonstrated associations between authors' conflicts of interest and proindustry conclusions in clinical research. Given the growing number of companies invested in CBD's commercial success, we decided to analyze the disclosed funding sources, conflicts of interest statements, author employment details, and CBD-related conclusions in a large sample of published articles on the characteristics, use, and therapeutic effects of cannabidiol.