Author Interviews, Endocrinology, JCEM / 28.04.2014

Dr. Dorte Glintborg PhD Senior Hospital Physician, PhD Dorte Glintborg, Department of Endocrinology, OUH Odense University HospitalMedicalResearch.com Interview with: Dr. Dorte Glintborg PhD Senior Hospital Physician, PhD Dorte Glintborg, Department of Endocrinology, OUH Odense University Hospital MedicalResearch.com: What are the main findings of this study? Dr. Glintborg: The main finding of the study is that one year’s metformin treatment is associated with a minor but significant weight loss in patients with PCOS irrespective of BMI at study inclusion. Treatment with oral contraceptives improves sex-hormone levels but is associated with at minor weight gain. Based on the study results, clinicians should consider the combined treatment with metformin and oral contraceptives in patients with PCOS.
Mediterranean Diet, NIH, Nutrition, Weight Research / 02.04.2014

Dr. Milan K Piya NIHR Clinical Lecturer in Diabetes and Endocrinology Warwick Medical School, University of Warwick; University Hospitals Coventry and Warwickshire NHS Trust Coventry, UKMedicalResearch.com Interview with: Dr. Milan K Piya NIHR Clinical Lecturer in Diabetes and Endocrinology Warwick Medical School, University of Warwick; University Hospitals Coventry and Warwickshire NHS Trust Coventry, UK MedicalResearch.com: What are the main findings of the study? Answer: Our studies have identified two main findings: Firstly that the size or frequency of the meal doesn’t affect the calories we burn in a day, but what matters most for losing weight is counting calories. Secondly, by carrying more weight, more endotoxin enters the circulation to cause inflammation and eating more often will exacerbate this risk which has been linked to metabolic diseases such as type-2 diabetes.
Author Interviews, Blood Pressure - Hypertension, Nutrition, Weight Research / 06.03.2014

Beverly B. Green, MD, MPH GroupHealth Research Institute Seattle WAMedicalResearch.com Interview with: Beverly B. Green, MD, MPH GroupHealth Research Institute Seattle WA   MedicalResearch.com: What are the main findings of the study? Dr. Green: We found that Group Health patients who were overweight and had hypertension were more likely to have lost 10 pounds in six months if they had secure online access to a dietitian than if they received only information and usual care. The patients really loved this intervention—and having access to a dietitian to work with them toward a healthier lifestyle. Although blood pressure and heart risk trended lower in the intervention group, the differences weren’t significant—unlike their weight.
Author Interviews, Lancet, Weight Research / 28.01.2014

Professor Sally Wyke Deputy Director, Institute of Health and Wellbeing Professor (Institute of Health and Wellbeing Social Sciences) The University of GlasgowMedicalResearch.com Interview with: Professor Sally Wyke Deputy Director, Institute of Health and Wellbeing Professor (Institute of Health and Wellbeing Social Sciences) The University of Glasgow MedicalResearch.com: What are the main findings of the study? Prof. Wyke: The FFIT programme was very effective.  The men who did the programme lost nine times as much weight as the men who did not.  On average, they lost over 5.5kg  (11lbs)and kept it off for the full 12 months. In addition, we found highly significant differences in favour of the intervention objectively-measured waist, percentage body-fat, systolic and diastolic blood pressure, and self-reported physical activity, diet and indicators of well-being and physical aspects of quality of life.
Author Interviews, Diabetes, Johns Hopkins, Weight Research / 19.07.2013

MedicalResearch.com Interview with: Nisa M. Maruthur, MD, MHS Assistant Professor of Medicine & Epidemiology The Johns Hopkins University Early Response to Preventive Strategies in the Diabetes Prevention Program MedicalResearch.com: What are the main findings of the study? Dr. Maruther: For patients engaged in a lifestyle intervention to prevent diabetes, weight loss early on (at 6 months) is an extremely strong predictor of whether they will develop diabetes down the road.  Even in the setting of substantial weight loss (>10%) at 6 months, it is still beneficial to lower fasting glucose.  These results are unique in that we previously understood that weight loss over time (years) is important to prevent diabetes, but now we know the impact of early weight loss on longer-term diabetes risk.
Author Interviews, BMJ, Diabetes, Exercise - Fitness, Nutrition, Weight Research / 10.04.2013

MedicalResearch.com eInterview with

Manuel Franco MD, PhD Associate Professor Department of Health Sciences, Public Health Unit Universidad de Alcalá Johns Hopkins Bloomberg School of Public Health Adjunct Associate Professor Dept. of Epidemiology mfranco@jhsph.edu

MedicalResearch.com: What are the main findings of the study? Dr. Franco: Population wide weight loss of about 5 kg was related with large decreases in diabetes and cardiovascular mortality. On the contrary, Body weight regain was related with an increase in diabetes prevalence, incidence, and mortality, as well as a deceleration in the previously declining rates of cardiovascular death.