Cancer Research

21 Sep Studying how to stop breast cancers from coming back

Posted at 19:49h in Breast Cancer

Medical researchers at the University of Leeds have come a step closer to understanding how to stop breast cancers from coming back. Their findings, published in the International Journal of Cancer, suggest that some novel drugs that are being developed to tackle other cancers should be considered as a future treatment...

19 Sep More immigrant women are getting mammograms now than a decade ago.

Posted at 20:38h in Breast Cancer, Mammograms, Medical Imaging

Fewer immigrant women receive mammograms than native-born American women, according to Penn State researchers, who note that more immigrant women are getting mammograms now than a decade ago. "Lack of access to health care persistently contributes to mammography screening disparities among immigrants," said Nengliang Aaron Yao, graduate student in health policy...

19 Sep New imaging technique visualizes cancer during surgery

Posted at 20:19h in Ovarian Cancer

Ovarian cancer is one of the most frequent forms of cancer that affect women. As tumors can initially grow unchecked in the abdomen without causing any major symptoms, patients are usually diagnosed at an advanced stage and have to undergo surgery plus chemotherapy. During the operation, surgeons attempt to remove...

14 Sep Depression and pain increase fatigue in breast cancer survivors

Posted at 23:43h in Breast Cancer

In Spain, 5-year survival following breast cancer diagnosis is more than 83%. Around 66% suffer fatigue following treatment. A Spanish research establishes the factors associated with tiredness in cancer survivors to improve their quality of life and rehabilitation. "Cancer-related fatigue is the symptom that most limits quality of life and is...

13 Sep Study: Gene therapy causes breast cancer stem cells to self-destruct

Posted at 00:12h in Breast Cancer, MD Anderson

Targeted agent avoids healthy cells, blocks proteins that prevent cell death in tumors HOUSTON -- Gene therapy delivered directly to a particularly stubborn type of breast cancer cell causes the cells to self-destruct, lowers chance of recurrence and helps increase the effectiveness of some types of chemotherapy, researchers at The University...

08 Sep Study: Chemotherapy is as effective before breast cancer surgery as after

Posted at 23:49h in Breast Cancer

Approach may help some women avoid mastectomy San Francisco, CA - Whether chemotherapy is given before or after breast-conserving therapy (BCT) does not have an impact on long-term local-regional outcomes, suggesting treatment success is due more to biologic factors than chemotherapy timing, according to a study by researchers at The University...

05 Sep Gene that predisposes people to leukemia discovered

Posted at 17:13h in Cancer Research, Genetic Research, Nature

Those at risk because of family history may soon obtain tests to detect the genetic error before symptoms emerge A new genetic defect that predisposes people to acute myeloid leukemia and myelodysplasia has been discovered. The mutations were found in the GATA2 gene. Among its several regulatory roles, the gene acts...

02 Sep Key function of mutation in BRCA1 gene discovered

Posted at 00:21h in Breast Cancer, Cancer Research, Ovarian Cancer

Richmond, Va. (September 1, 2011) –It is widely known that mutations in the breast cancer susceptibility 1 (BRCA1) gene significantly increase the chance of developing breast and ovarian cancers, but the mechanisms at play are not fully understood. Now, researchers at Virginia Commonwealth University Massey Cancer Center have shown that...

19 Aug PET scans confirm effectiveness of estrogen-blocking drugs in breast cancer patients

Posted at 23:47h in Breast Cancer, Cancer Research, Radiology

SEATTLE – For the first time, researchers at Seattle Cancer Care Alliance have demonstrated the feasibility of using serial positron emission tomography (PET) scans, using a special estrogen-containing isotope, to confirm the relative effectiveness of estrogen-blocking and estrogen-depleting therapy in patients with metastatic breast cancer. The results of the research...

16 Aug Breast Feeding & Breast Cancer in African-American women

Posted at 22:47h in Breast Cancer, Cancer Research

Investigators from the Boston University's Slone Epidemiology Center have reported findings that may shed light on why African American women have a disproportionately higher risk of developing more aggressive and difficult-to-treat breast cancers, specifically estrogen and progesterone receptor negative (ER-/PR-) cancers. The study, which appears online in Cancer Epidemiology, Biomarkers &...

16 Aug Vitamin D and protection against the Advance of Colon Cancer

Posted at 22:36h in Colon Cancer, PLoS, Vitamin D

A study conducted by VHIO researchers confirms that a lack of vitamin D increases the aggressiveness of colon cancer The indication that vitamin D and its derivatives have a protective effect against various types of cancer is not new. In the field of colon cancer, numerous experimental and epidemiological studies show...

11 Aug Team reports genetic sequences most common bladder cancer

Posted at 21:45h in Cancer Research, Nature

August 11, 2011 (Aurora, CO)--In an article published online this week in Nature Genetics, a University of Colorado Cancer Center team in partnership with universities in China and Denmark. Recognizing the genetic mutations that make bladder cancer cells different than their healthy neighbors may allow early genetic screenings for cancer and...

11 Aug Report: NSAIDS reduce the severity of postpartum breast cancers in animal models

Posted at 21:39h in Breast Cancer, Nature

Published online on Aug. 7, 2011, the journal Nature Medicine reports that non-steroidal anti-inflammatory drugs including ibuprofen reduce the severity of postpartum breast cancers in animal models. “We caution patients and providers that because a mother’s body is undergoing radical changes during this time, we can’t yet speak to the...

04 Aug Scientists map genetic mutations in the second-most common form of brain cancer, oligodendroglioma

Posted at 18:44h in Brain Cancer - Brain Tumors

Johns Hopkins Kimmel Cancer Center scientists have completed a comprehensive map of genetic mutations occurring in the second-most common form of brain cancer, oligodendroglioma. The findings, reported in the Aug. 4 issue of Science, also appear to reveal the biological cause of the tumors, they say. To create the map, the...

03 Aug New Breast Cancer Strategies Presented at Conference

Posted at 20:24h in Breast Cancer, Cancer Research, Nature

ORLANDO, Fla. — August 3, 2011 — In their lifetime, women have more than a 12 percent risk of being diagnosed with breast cancer. 1 This week, research on novel approaches to breast cancer treatment is being presented at the Era of Hope (EOH) conference, a scientific meeting hosted by...

03 Aug Potential Links between Maternal Diet in Pregnancy and Breast Cancer in Daughters

Posted at 20:18h in Breast Cancer

ORLANDO, Fla. — August 3, 2011 — During pregnancy, women are counseled to refrain from consuming certain types of foods, beverages and medications in order to avoid jeopardizing the health and development of the fetus. In fact, the American Pregnancy Association has a list of a dozen items they recommend...

03 Aug Exploring Breast Cancer Mechanisms of Spread and Treatment Options

Posted at 20:15h in Breast Cancer

ORLANDO, Fla. — August 3, 2011 — Research into new methods to prevent and slow metastatic breast cancer will be presented this week at the Era of Hope conference, a scientific meeting hosted by the Department of Defense Breast Cancer Research Program (BCRP). Approximately 6 percent of women with breast...

03 Aug Simpler test to decide which lung cancer pts benefit from crizotinib

Posted at 01:10h in Lung Cancer

A relatively simple and inexpensive method may be used to determine whether a lung cancer patient is a candidate for crizotinib therapy, according to research published in the August issue of the Journal of Thoracic Oncology, the official monthly journal of the International Association for the Study of Lung Cancer...

01 Aug Combining dasatinib with Tamoxifen, may overcome Tamoxifen resistance in breast cancer

Posted at 20:45h in Breast Cancer

August 1 20100 PHILADELPHIA—Taking a leukemia chemotherapy drug may help breast cancer patients who don't respond to tamoxifen overcome resistance to the widely-used drug, new research from the Kimmel Cancer Center at Jefferson suggests. Interestingly, researchers found that taxoxifen combined with dasatinib, a protein-tyrosine kinase inhibitor, reverses the chemo-resistance caused by cancer-associated...

29 Jul Study examines how blood protein levels change as breast cancer develops before it is clinically detectable

Posted at 01:38h in Breast Cancer, Nature

SEATTLE – Using a "systems biology" approach – which focuses on understanding the complex relationships between biological systems – to look under the hood of an aggressive form of breast cancer, researchers for the first time have identified a set of proteins in the blood that change in abundance long...

28 Jul Breast density tied to specific types of breast cancer

Posted at 15:16h in Breast Cancer, Cancer Research

Women with breasts that appear dense on mammograms are at a higher risk of breast cancer and their tumors are more likely to have certain aggressive characteristics than women with less dense breasts, according to a study published online July 27 in the Journal of the National Cancer Institute. Mammographic breast...

27 Jul Scientists Develop New Therapy for HER2-Positive Breast Cancer

Posted at 10:38h in Breast Cancer, Cancer Research

Newswise — PHILADELPHIA — Patients with HER2-positive breast cancer may have an alternative therapy when they develop resistance to trastuzumab, also known as Herceptin, according to a laboratory finding published in Clinical Cancer Research, a journal of the American Association for Cancer Research. Jacek Capala, Ph.D., D.Sc., an investigator at the...

26 Jul Hormone therapy may be hazardous for men with heart conditions

Posted at 18:00h in Cancer Research, Hormone Therapy, Prostate Cancer

Fairfax, Va., July 26, 2011 – Adding hormone therapy to radiation therapy has been proven in randomized clinical trials to improve overall survival for men with intermediate- and high-risk prostate cancer. However, adding hormone therapy may reduce overall survival in men with pre-existing heart conditions, even if they have high-risk...

26 Jul New Avenues Open Up for Mesothelioma Targeted Therapy

Posted at 00:12h in Cancer Research

Newswise — July 25, 2011 (Philadelphia, PA) --Researchers from the lab of Antonio Giordano, M.D., Ph.D., the Founder and Director of the Sbarro Institute for Cancer Research and Molecular Medicine, have identified new potential anti-tumor agents that might be effective in treating mesothelioma, one of the deadliest cancer tumors. Scientists tested...

25 Jul Study examines screening for pancreatic cancer in high-risk populations

Posted at 19:43h in Cancer Research, Dartmouth

OAK BROOK, Ill. – July 25, 2011 – Researchers from New England report in a new study that using a tumor marker, serum CA 19-9, combined with an endoscopic ultrasound if the tumor marker is elevated, is more likely to detect stage 1 pancreatic cancer in a high-risk population than...

24 Jul 2 genetic variations predict second cancers after radiation for children with Hodgkin lymphoma

Posted at 23:01h in Cancer Research, Nature, Sloan Kettering, University of Pennsylvania

A genome-wide association study published in the August issue of Nature Medicine has found two tiny genetic variations that can predict which patients with Hodgkin's lymphoma are most likely to develop radiation-induced second cancers years after treatment. Knowing in advance who is at risk could help physicians tailor treatment to...