Compare Rybelsus and Metformin for type 2 diabetes treatment. Discover their benefits, side effects, effectiveness, weight impact, and cost differences....
Compare Rybelsus and Metformin for type 2 diabetes treatment. Discover their benefits, side effects, effectiveness, weight impact, and cost differences....
Dr. Malavazos[/caption]
Dr. Alexis Elias Malavazos
Endocrinology Unit
Clinical Nutrition and Cardiovascular Prevention Service,
IRCCS Policlinico
Unit of Radiology, IRCCS Policlinico
San Donato, San Donato Milanese, Italy
MedicalResearch.com: What is the background for this study?
Response: Psoriasis is a systemic inflammatory disease often associated with obesity and type-2 diabetes (T2D). The inflammatory process of psoriasis can target adipose tissue depots, particularly those surrounding the heart and the coronary arteries, exposing them to an increased risk of cardiovascular disease.
Statement from Dr. Robert Gabbay, Chief Scientific and Medical Officer for the ADA, regarding the Lilly statement this of April...
Amgad Mentias, MD MS FACC FESC
Assistant Professor, CCLCM
Section of Clinical Cardiology, Heart and Vascular Institute.
Cleveland, OH 44195
MedicalResearch.com: What is the background for this study?
Response: There is evidence that bariatric or weight loss surgery can decrease the risk of heart attack, stroke, and death in young and middle age patients with obesity and diabetes. However, the evidence is less clear for older patients and patients without diabetes. There is also no long-term data on outcomes of bariatric surgery in the Medicare beneficiaries.
So, in our study, we aimed to report long-term outcomes of bariatric surgery from a contemporary nationwide cohort from the US, while also looking into outcomes in patients older than 65 years, and patients without type 2 diabetes specifically.
Joe Whittaker, MSc[/caption]
Joe Whittaker, MSc
Nutritionist
MedicalResearch.com: What is the background for this study?
Response: There are several studies showing a generational decline in men's testosterone levels, beginning in the 1970s. This is due to a variety of factors such as poorer diets, lack of physical activity, and increasing toxin exposure. Therefore, there is intense research interest in ways we can optimise testosterone levels, to combat this generational decline.
Some well-known studies have found low-carbohydrate diets boost testosterone levels, but others have show the reverse effect. So, to settle the controversy we gathered and reanalysed all known studies on the topic. There was also the question of high protein diets and their effects on testosterone, which are currently disputed.
Jeff Ruby, JD, MBA, Founder and Chief Executive Officer
Leonard Fensterheim, MPH
Vice President of Analytics
MedicalResearch.com: What is the background for this study? What are common weight-change findings during the pandemic?
Obesity has been linked to increased risk of serious complications and the need for costly medical utilization – all of which has been exacerbated by the COVID-19 pandemic. There has been an increase of imposed restrictions that impact healthy lifestyles – the closing of gyms as an example – leading to additional stress and the complete disruption of daily lives. It’s no surprise that many people have gained weight since the beginning of the pandemic.
According to the Centers for Disease Control and Prevention (CDC), before the pandemic about 40% of Americans had obesity in the United States. This was already an alarming figure, but given that the American Psychological Association found that 42% of U.S. adults report undesired weight gain, with an average gain of 29 lbs. since the start of the pandemic, we expect that percentage has continued to grow.
Against this backdrop, Newtopia sought to evaluate the impact of a guided habit change program on weight loss for 12 months during the COVID-19 pandemic.
Method:
Dr. Hoff[/caption]
Anna Carolina Hoff, MD
Lead researcher on the study
Founder and Clinical Director
Angioskope Brazil
São José dos Campos
MedicalResearch.com: What is the background for this study?
Response: Obesity is a chronic disease that has become a global pandemic, and its prevalence continues to increase. Overweight (Body Mass Index (BMI) ≥ 27 kg/m2) and obesity (BMI ≥ 30kg/m2) lead to numerous clinical comorbidities, including metabolic, cardiovascular, oncologic, and mental health disorders. It is challenging to achieve significant and sustained weight loss with diet and lifestyle modification alone. Additionally, a reversal of obesity-related co-morbidities and improvement in quality of life entails a percent total body weight loss (%TBWL) of between 5-10%, which is rarely achieved with medications alone. The Endoscopic Sleeve Gastroplasty (ESG) results in a %TBWL between 14.6%-19.7% at 18-24 months, and improvements in systolic blood pressure (SBP), HbA1c, and dyslipidemia at 12 months.
Prof. Koehler[/caption]
Prof. Dr. Karsten Koehler
Department of Sport and Health Sciences
Technical University of Munich
MedicalResearch.com: What is the background for this study?
Response: The primary background is the phenomenon that most people fail to loose (meaningful) weight through exercise alone, which is related to what we call compensatory eating – an increase in food intake to compensate for the increased energy expenditure of exercise. This is been described in a number of studies and is considered a key weight loss barrier – yet few have come up with solutions to overcome this problem. Therefore, we wanted to see if the timing of food choices has an impact on how much and what we want to eat in the context of exercise.