OBGYNE
22 Aug Gestational Diabetes Mellitus and Sleep Apnea
Posted at 01:59h
in Author Interviews, Diabetes, JCEM, OBGYNE, Obstructive Sleep Apnea, Sleep Disorders
MedicalResearch.com: Interview with
Sirimon Reutrakul MD
Section of Endocrinology Department of Medicine
Rush University Medical Center
Chicago, Illinois 60612
MedicalResearch.com: What are the main findings of the study?
Answer: We found a strong association between obstructive sleep apnea and gestational diabetes mellitus. In pregnant women diagnosed with gestational diabetes, the risk of obstructive sleep apnea is increased nearly 7-fold compared to those without gestational diabetes. In addition, we found that in non-diabetic women, pregnancy is associated with more disrupted sleep.
15 Aug Maternal Obesity Raises Health Risks, Even for Their Adult Children
MedicalResearch.com Interview with: Rebecca M Reynolds, Professor of Metabolic Medicine Endocrinology Unit, BHF/University Centre for Cardiovascular Science, University of Edinburgh, Queen’s Medical Research Institute, Edinburgh EH14 6TJ, UK MedicalResearch.com: What are the main findings of the study? Answer: We found that the adult offspring of women who were obese at the start of pregnancy were 35% more likely to die prematurely than offspring of normal-weight women. We also found that children born to mothers who were overweight when they became pregnant had an 11% increased risk of premature death. Adult offspring of mothers who were obese were also at increase risk of hospital admissions for cardiovascular events.01 Aug Vulvar Cancer: Racial and Age Disparities
Hemodialysis.com Interview with:: Marcela G. del Carmen, M.D., M.P.H Division of Gynecologic Oncology, Vincent Obstetrics and Gynecology Massachusetts General Hospital, 55 Fruit Street, Yawkey 9 E Boston, Massachusetts MedicalResearch.com: What are the main findings of the study? Answer: The study sample included 7,973 women, including 7,363 (92.3%) whites and 610 (7.7%) AA, diagnosed with vulvar cancer from 1973 to 2009. African American women were younger and had a higher rate of distant metastasis compared to white women. African American women were more likely to be treated by radiaton therapy and less likely to receive survival therapy. Although the study found that compared to white women, African Americans were more likely to be younger and have more advanced disease upon diagnosis, they had lower rates of vulvar cancer related mortality compared to white women.26 Jul Should the Ovaries be Removed at Time of Hysterectomy for Benign Disease?
MedicalResearch.com Interview with: Catherine A. Matthews, MD Associate Professor and Division Chief Urogynecology and Reconstructive Pelvic Surgery University of North Carolina, Chapel Hill MedicalResearch.com: What are the main findings of the study? Dr. Matthews: Women under 50 should try and preserve their ovaries at the time of hysterectomy for benign disease; however, women over 50 should consider elective ovarian removal as a way to reduce ovarian cancer. There is no adverse impact on cardiovascular, bone or sexual health in women over 50 who elect ovarian removal.24 Jul Pregnancy-Related Hospitalizations – Venous Thromboembolism Rates
MedicalResearch.com Interview with: Sheree Boulet, DrPH, MPH Assisted Reproductive Technology Surveillance and Research Team Women's Health and Fertility Branch Division of Reproductive Health Centers for Disease Control and Prevention MedicalResearch.com: What are the main findings of the study? Dr. Boulet: Between 1994-2009, the rate of pregnancy-related hospitalizations with venous thromboembolism (VTE) increased by 14%. We also found that the prevalence of hypertension, obesity, diabetes, and heart disease increased over the same time period for pregnancy hospitalizations with VTE.19 Jul Threatened Preterm Labor : Cost of Hospital Admissions
MedicalResearch.com Interview with: Robert E. Garfield, PhD Department of Perinatology, Division of Obstetrics and Gynecology University Medical Centre Ljubljana, Slovenia Costs of Unnecessary Admissions and Treatments for “Threatened Preterm Labor” MedicalResearch.com :What are the main findings of the study? Dr. Garfield: Unnecessary admissions and treatments for “threatened preterm labor” are still part of everyday clinical practice and contribute to exploding healthcare costs. This happens despite substantial evidence that measuring CL by trans-vaginal ultrasound can help to avoid needless interventions due to the high negative predictive values of this test.18 Jul Pre-Term Deliveries Associated with Future Risk of Cardiovascular Events
MedicalResearch.com Interview with Prof. Eyal Sheiner MD PhD Senior Obstetrician
Soroka Medical Center, Israel
MedicalResearch.com: What are the main findings of the study? Dr. Sheiner: The study was aimed to investigate whether a history of preterm delivery (PTD) poses a risk for subsequent maternal long-term cardiovascular morbidity. During the study period 47,908 women met the inclusion criteria; 12.5% (n=5992) patients delivered preterm. During a follow-up period of more than ten years, patients with PTD had higher rates of simple as well as complex cardiovascular events and higher rate of total cardiovascular related hospitalizations. A linear association was found between the number of previous PTD and future risk for cardiovascular hospitalizations (5.5% for two or more PTD, 5.0% for one PTD vs. 3.5% in the comparison group; P<0.001). The association remained significant for spontaneous vs. induced PTD and for early (<34 weeks) as well as late (34-36+6 weeks) PTD. In a Cox proportional hazards model that adjusted for pregnancy confounders such as labor induction, diabetes mellitus, preeclampsia and obesity, PTD was independently associated with cardiovascular hospitalizations (adjusted HR 1.4, 95% CI 1.2-1.6).06 Jul Is Dairy intake Protective against Uterine Fibroid Risk?
MedicalResearch.com Interview with: Dr. Lauren A. Wise Slone Epidemiology Center 1010 Commonwealth Avenue Boston, MA MedicalResearch.com: What are the main findings of the study? Dr. Wise: We found that the strong inverse association between dairy and uterine fibroids in black women in the Black Women's Health Study is not explained by percent European ancestry.04 Jul Risk of Adverse Pregnancy Outcomes: Anemia and Prenatal Iron Use
MedicalResearch.com Interview with Batool Haider, MD, MS, DSc candidate Departments of Epidemiology and Nutrition School of Public Health Harvard University Anaemia, prenatal iron use, and risk of adverse pregnancy outcomes: systematic review and meta-analysis MedicalResearch.com: What are the main findings of the study? Dr. Haider: The main findings of the study are that iron use in the prenatal period increased maternal mean haemoglobin concentration by 4.59 (95% confidence interval 3.72 to 5.46) g/L compared with controls and significantly reduced the risk of anaemia (relative risk 0.50, 0.42 to 0.59), iron deficiency (0.59, 0.46 to 0.79), iron deficiency anaemia (0.40, 0.26 to 0.60), and low birth weight (0.81, 0.71 to 0.93). The effect of iron on preterm birth was not significant (relative risk 0.84, 0.68 to 1.03). Analysis of cohort studies showed a significantly higher risk of low birth weight (adjusted odds ratio 1.29, 1.09 to 1.53) and preterm birth (1.21, 1.13 to 1.30) with anaemia in the first or second trimester. Exposure-response analysis indicated that for every 10 mg increase in iron dose/day, up to 66 mg/day, the relative risk of maternal anaemia was 0.88 (0.84 to 0.92) (P for linear trend<0.001). Birth weight increased by 15.1 (6.0 to 24.2) g (P for linear trend=0.005) and risk of low birth weight decreased by 3% (relative risk 0.97, 0.95 to 0.98) for every 10 mg increase in dose/day (P for linear trend<0.001). Duration of use was not significantly associated with the outcomes after adjustment for dose. Furthermore, for each 1 g/L increase in mean haemoglobin, birth weight increased by 14.0 (6.8 to 21.8) g (P for linear trend=0.002); however, mean haemoglobin was not associated with the risk of low birth weight and preterm birth. No evidence of a significant effect on duration of gestation, small for gestational age births, and birth length was noted.05 Apr Risk factors for first venous thromboembolism around pregnancy: a population based cohort study from the United Kingdom
Author Interview with Dr Matthew Grainge Achieved his BSc in Statistics at Reading University and his MSc in Medical Statistics at the University of Leicester, before going on to complete his PhD on the topic of cervical screening and human papillomavirus at the University of Nottingham. MedicalResearch.com: What are the main findings...