Author Interviews, Cannabis, JAMA / 25.01.2025
Columbia University Documents Relationship Between Medical and Recreational Cannabis Laws and Opioid Use
MedicalResearch.com Interview with:
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Dr. Martins[/caption]
Silvia S. Martins, MD, PhD
Associate Dean for Faculty
Professor of Epidemiology
Director, Substance Use Epidemiology Unit
Co-Director, Substance Abuse Epidemiology T32 Program
Department of Epidemiology
Columbia University Mailman School of Public Health
New York, NY
MedicalResearch.com: What is the background for this study?
Response: Much has been speculated on whether the enactment of medical and recreational cannabis laws can have a role in decreasing prescriptions for opioid pain relievers, opioid use and misuse, opioid use disorder, and overdose in the U.S. However, findings on the associations of medical cannabis laws alone and recreational cannabis las + medical cannabis laws with opioid-related outcomes are mixed.
By the end of 2019, 32 U.S. states had adopted medical marijuana laws (MCL) alone. All states that went on to adopt recreational marijuana laws (RCL) had previously adopted an MCL.
Dr. Martins[/caption]
Silvia S. Martins, MD, PhD
Associate Dean for Faculty
Professor of Epidemiology
Director, Substance Use Epidemiology Unit
Co-Director, Substance Abuse Epidemiology T32 Program
Department of Epidemiology
Columbia University Mailman School of Public Health
New York, NY
MedicalResearch.com: What is the background for this study?
Response: Much has been speculated on whether the enactment of medical and recreational cannabis laws can have a role in decreasing prescriptions for opioid pain relievers, opioid use and misuse, opioid use disorder, and overdose in the U.S. However, findings on the associations of medical cannabis laws alone and recreational cannabis las + medical cannabis laws with opioid-related outcomes are mixed.
By the end of 2019, 32 U.S. states had adopted medical marijuana laws (MCL) alone. All states that went on to adopt recreational marijuana laws (RCL) had previously adopted an MCL.
Prof. Guohua Li[/caption]
MedicalResearch.com Interview with:
Guohua Li, MD, DrPH
Finster Professor of Epidemiology and Anesthesiology
Columbia University Irving Medical Center
MedicalResearch.com: What is the background for this study? How was the ADHD diagnosis determined?
Response: The reported prevalence of ADHD in children and young adults in the United States has more than doubled since the 1990s because of improved diagnosis. Currently, ADHD affects about 13 percent of children under 18 years of age and eight percent of adults under 45 years of age. Little is known about the prevalence of ADHD in older adults although it is estimated that ADHD symptoms may persist throughout the lifespan in about one-third of children diagnosed with the disorder. Diagnostic criteria for adulthood ADHD include having five or more relevant symptoms, adverse impact on social, academic, and occupational activities, and onset of symptoms before age 12.
In this study, ADHD status is determined based on an affirmative response to the question of whether the participant had ever had ADHD or had ever been told by a doctor or other health professional that he or she had ADHD.
Dr. Stingone[/caption]
Jeanette Stingone PhD
Assistant Professor, Epidemiology
Mailman School of Public Health
Columbia University
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Lead is a well-established neurotoxin, particularly when exposure occurs early in life and in childhood. Associations between elevated blood lead levels and lower scores on tests of neurodevelopment and cognition are seen consistently across studies, even when examining lower levels of exposure.
While reducing exposure to lead is the primary intervention to prevent these adverse outcomes, there aren’t many interventions designed to support the neurodevelopment of children who have been exposed to lead. Some municipalities consider elevated blood lead levels as a criteria for inclusion in Early Intervention programs. Early Intervention programs are mandated under the Individuals with Disabilities Education Act and provide services for children younger than 3 years old with disabilities or developmental delays.
The objective of this study was to compare 3rd grade standardized test scores among children who had elevated blood lead levels early in life to see if children who had received Early Intervention services performed better on these tests than those who did not receive services. Using matching methods and an existing administrative data linkage of children who were born and attended public school in New York City, we observed that children exposed to lead who received Early Intervention services scored higher on standardized tests in both math and English Language arts than children exposed to lead who did not receive services.