[caption id="attachment_72732" align="aligncenter" width="500"] Photo by Andrea Piacquadio[/caption]
Getting a good night’s sleep is paramount if you are to lead a healthy and productive life. Our medical practitioners tell us that most people need to get at least 7 to 8 hours of sleep every single night, but that’s a lot easier said than done. We lead very high-stress lives, if we are trying to hold down a full-time position, or we are trying to take care of our other family members. It isn’t any wonder that a good night’s sleep proves to be elusive for many.
If you struggle with sleep apnea, there is assistance out there, however, and it comes in the form of
ResMed machines, which use modern technology to help you get that night’s sleep that your body deserves. Another selling point is that they are incredibly affordable, and they are available to you right now. This is just one top tip to help you get the best night’s sleep in Australia, and the following are others.
Photo by Andrea Piacquadio[/caption]
Getting a good night’s sleep is paramount if you are to lead a healthy and productive life. Our medical practitioners tell us that most people need to get at least 7 to 8 hours of sleep every single night, but that’s a lot easier said than done. We lead very high-stress lives, if we are trying to hold down a full-time position, or we are trying to take care of our other family members. It isn’t any wonder that a good night’s sleep proves to be elusive for many.
If you struggle with sleep apnea, there is assistance out there, however, and it comes in the form of
ResMed machines, which use modern technology to help you get that night’s sleep that your body deserves. Another selling point is that they are incredibly affordable, and they are available to you right now. This is just one top tip to help you get the best night’s sleep in Australia, and the following are others.
The ResMed AirSense™ 10 AutoSet™ Tri-Pack is an essential package designed for individuals with sleep apnea who require consistent and effective therapy. This article delves into the key features benefits and frequently asked questions surrounding the ResMed AirSense™ 10 AutoSet™ Tri-Pack offering a guide to help you understand its significance in sleep apnea treatment.
What is the ResMed AirSense™ 10 AutoSet™ Tri-Pack?
The 
Dr. Avinesh Bhar[/caption]
Dr. Parekh[/caption]
Ankit Parekh, PhD
Director of the Sleep And Circadian Analysis (SCAN) Group
Assistant Professor of Medicine
(Pulmonary, Critical Care and Sleep Medicine)
Icahn School of Medicine at Mount Sinai
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Sleep apnea is associated with incident cardiovascular disease, and is a common chronic condition affecting over a billion people worldwide. In diagnosing and treating sleep apnea, it is imperative to establish the type of sleep apnea—whether it is obstructive or central sleep apnea. The differential contribution of central vs. obstructive sleep apnea toward incidental cardiovascular disease in those with significant sleep apnea has not been well studied.
Our group has developed an automated algorithm that deduces on a breath-by-breath level whether reductions in airflow are predominantly due to obstructive or central phenomena. Our algorithm uses several features that are known to be key in distinguishing the type of events and derives a probability of obstruction across each “small” (reduced amplitude) breath. The breath-by-breath probability is then used to determine whether a patient’s burden of sleep apnea is predominantly obstructive or central.
In this work, we analyzed sleep study data from The Osteoporotic Fractures in Men (MrOS) cohort (N=2793) consisting of elderly men, across two visits separated on average by 6.5 years, and derived the probability of obstruction on a breath-by-breath level. The median probability of obstruction for each subject was computed and analyzed against outcomes of cardiovascular disease. We also assessed the stability of the metric in those without any prevalent cardiovascular disease. We find that median probability of obstruction was stable across the two visits, and those with any incident cardiovascular disease had a lower median probability of obstruction: patients with incident cardiovascular outcomes had a significant burden of sleep apnea that was predominantly “central” in nature.
Dr. Traverso[/caption]
Giovanni Traverso MD PhD
Karl Van Tassel (1925) Career Development Professor
Department of Mechanical Engineering
Koch Institute of Integrative Cancer Research
Division of Gastroenterology
Brigham and Women’s Hospital
Harvard Medical School, Boston, MA, USA
MedicalResearch.com: What is the background for this study?
Response: I think its always important to acknowledge that this is a big team effort. We have the teams from MIT, Celero Systems, West Virgnia University (WVU) and Brigham and Women’s Hospital (BWH) all working together on this. For this study, Celero prototyped the devices that we tested in pre-clinical (Swine) models and in a first-in-human study with the team at WVU.
Our lab focuses on the development of ingestible devices for drug delivery and sensing and these have informed the development of these efforts as you can see.
Dr. Cortese[/caption]
Rene Cortese, PhD
Assistant Professor
Department of Child Health – Child Health Research Institute
Department of Obstetrics, Gynecology and Women’s Health
School of Medicine
Core Faculty - MU Institute for Data Science and Informatics
University of Missouri
Columbia, MO 65212
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Obstructive sleep apnea (OSA) affects 22 million people in the U.S. and is linked to a higher risk of hypertension, heart attacks, stroke, diabetes, and many other chronic conditions.
We have found that untreated OSA also accelerates the biological aging process, and that appropriate treatment can slow or possibly reverse the trend. Age acceleration testing involves a blood test that analyzes DNA and uses an algorithm to measure a person’s biological age. The phenomenon of a person’s biological age surpassing their chronological age is called “epigenetic age acceleration” and is linked to overall mortality and to chronic diseases.
Dr. Dunietz[/caption]
Galit Levi Dunietz MPH, PhD
Assistant Professor
Dr. Braley[/caption]