MedicalResearch.com Interview with: Dr. David O'Brart
Keratoconus Research Institute, Department of Ophthalmology
St. Thomas' Hospital, London, United Kingdom
Medical Research: What are the main findings of the study?Dr. O'Brart: There was a slight but significant increase in myopic spherical equivalent refractive error after Photorefractive Keratectomy between 1 and 20 years, particularly in those under 40 at the time of treatment and female patients.
Corneal curvature/power remained unchanged but axial length increased over two decades. The procedure was safe with no long-term sight-threatening complications and improvements in CDVA (corrected distance visual acuity) and corneal transparency with time.
(more…)
MedicalResearch.com Interview with: Szilárd Kiss, MD
Director of Clinical Research
Director of Compliance Associate Professor of Ophthalmology
Weill Cornell Medical College NewYork-Presbyterian Hospital
New York, New York 10021
Medical Research: What is the background for your study?Dr. Kiss: There has been a good deal of publicity about bevacizumab (Avastin; a Genetech/Roche antibody originally developed for treatment of cancer but now used widely to treat macular degeneration and diabetic retinopathy) being prepared by (mostly unregulated) compounding pharmacies for injection into the eye, and being associated with pathogen contamination.
(more…)
MedicalResearch.com Interview with:Mary G. Lynch, MD
Professor of Ophthalmology
Atlanta Veterans Affairs Medical Center Decatur, Georgia.
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia
Medical Research: What are the main findings of the study?
Dr. Lynch:
Since 2006, the VA has been systematically using teleretinal screening of patients with diabetes to screen for retinopathy in the Primary Care Clinics. Under this program, 90% of veterans with diabetes are evaluated on a regular basis. A number of patients who are screened have findings that warrant a face-to-face ophthalmic exam. No information exists on the effect of such a program on medical center resources.
1,935 patients underwent teleretinal screening through the Atlanta VA over a 6 month period. We reviewed the charts of the 465 (24%) of the patients who were referred for a face to face exam in the Eye Clinic.
Data was collected for these patients to determine the reasons for referral, the accuracy of the teleretinal interpretation, the resources needed in the Eye Clinic of the Medical Center to evaluate and care for the referred patients over a two year period and possible barriers to patient care.
Of the 465 patients referred for an exam, 260 (55.9%) actually came in for an exam. Community notes were available for an additional 66 patients. Information was available for 326 (70.1%) of the referred patients.
The most common referring diagnoses were nonmacular diabetic retinopathy (43.2% of referrals), nerve related issues (30.8%), lens or media opacity (19.1%), age-related macular degeneration (12.9%) and diabetic macular edema (5.6%).
16.9% of the referred patients had 2 or more concurrent problems that put them at high risk for visual loss.
The percentage agreement between teleretinal screening and the ophthalmic exam was high: 90.4%. Overall sensitivity was 73.6%. The detection of diabetic macular edema had the lowest sensitivity.
A visually significant condition was detected for the first time through teleretinal screening for 142 of the patients examined (43.6%).
The resource burden to care for referred patients was substantial.
36% of patients required 3 or more visits over the ensuing 2 year period.
The treatment of diabetic macular edema had the highest resource use involving on average 5 clinic visits, 6 diagnostic procedures and 2 surgical procedures
The most common non-refractive diagnostic procedures were visual fields and optical coherence tomography.
The average cost to care for the referred patients (in Medicare dollars) in work RVUs alone was approximately $1,000 per patient. The cost to care for a patient with diabetic macular edema was $2673.36.
MedicalResearch.com Interview with: Louis R. Pasquale, MD
Channing Division of Network Medicine
Department of Ophthalmology
Harvard Medical School, Massachusetts Eye and Ear Infirmary
Boston, Massachusetts
Medical Research: What are the main findings of the study?Dr. Pasquale: We found that more time spent outdoors in summer was associated with increased risk of exfoliation syndrome.
(more…)
MedicalResearch.com Interview with Ronald C Gentile, MD, FACS, FASRS
Professor of Ophthalmology
Chief, Ocular Trauma Service (Posterior Segment)
Surgeon Director
The New York Eye and Ear Infirmary of Mount Sinai
New York, NY 10003
President: operationrestorevision.org
Medical Research: What are the main findings of the study?Dr. Gentile:We had three main findings in our study on the microbiological spectrum and antibiotic sensitivity in endophthalmitis over the past twenty- five years at the New York Eye and Ear Infirmary of Mount Sinai.
First Finding: The first main finding of the study was that there has not been any major change in the types of organisms causing endophthalmitis over the past 25 years. The most common cause of endophthalmitis in the study was bacteria, 95%, with most, 85%, being Gram-positive bacteria. The most prevalent organisms isolated were coagulase-negative staphylococcus, making up about 40% of the cases. This was followed by Streptococcus viridans species in about 12% and Staphylococcus aureus in about 11%. Gram-negative organisms accounted for about 10% and fungi for about 5%.
Second Finding: The second main finding of the study was that the current empiric intravitreal antibiotics used for treating endophthalmitis, vancomycin and ceftazidime, continue to be an excellent choice. The overwhelming majority of microorganisms causing endophthalmitis are susceptible to this combination. Over 99% of the Gram-positive isolates were susceptible to the vancomycin and about 92 percent of the Gram-negative isolates were susceptible to ceftazidime.
Third Finding: The third main finding of the study was that there was increasing microbial resistance to eight antibiotics including cefazolin, cefotetan, cephalothin, clindamycin, erythromycin, methicillin/oxacillin, ampicillin, ceftriaxone and decreasing microbial resistance to three antibiotics including gentamicin, tobramycin, and imipenem. For example, Staph Aureus isolates resistant to methicillin increased from 18% in the late 1980s to just over 50% this past decade while gentamicin-resistance endophthalmitis isolates decreased during the same time period from 42% to 6%.
(more…)
MedicalResearch.com Interview with: Rohit Varma, MD, MPH
Grace and Emery Beardsley Professor and Chair
USC Department of Ophthalmology
Director, USC Eye Institute
Associate Dean for Strategic Planning and Network Development
Keck School of Medicine of USC
Medical Research: What are the main findings of the study?Dr. Varma: Our research demonstrates African-Americans bear a heavier burden of diabetic macular edema (DME), one of the leading causes of blindness in diabetic patients in the United States, compared to Non-Hispanic whites. The study points to a need for improved screening and greater attention to vision loss by clinicians and patients particularly those who are at high risk of developing diabetic macular edema.
(more…)
MedicalResearch.com Interview with: Helen A. Mintz-Hittner, M.D., F.A.C.S.
Alfred W. Lasher, III, Professor of Ophthalmology
Department of Ophthalmology and Visual Science
The University of Texas Health Science Center
at Houston-Medical School
Cizik Eye Clinic
Medical Research: What are the main findings of the study?Dr. Mintz-Hittner:
For retinopathy of prematurity (ROP), at age 2 ½ years, intravitreal bevacizumab (IVB) injections cause less myopia (nearsightedness) in diopters (D) compared to conventional laser therapy (CLT):f
or Zone I: -1.51 D versus -8.44 D (7 diopters difference: p = 0.001.
for Posterior Zone II: -0.58 D versus -5.83 D (5 diopters difference: p = 0.001.
MedicalResearch.com Interview with:Pradeep Ramulu
Wilmer Eye Institute at John Hopkins
Baltimore, MD
MedicalResearch What are the main findings of the study?Answer: The main finding is that people with vision loss, especially women and people with other diseases such as diabetes, are much less likely to be working.
(more…)
MedicalResearch.com Interview with: Ben Mead
Molecular Neuroscience Group
Neurotrauma and Neurodegeneration Section
School of Clinical and Experimental Medicine
University of Birmingham, Birmingham
Medical Research: What are the main findings of the study?Answer: Traumatic and neurodegenerative disease of the retina lead to an irreversible loss of retinal ganglion cells (RGC) which are the neuronal cells located in the inner retina that transmit visual signals to the brain. Thus RGC injury results in visual defects which can ultimately progress into permanent blindness. One promising therapeutic approach is the use of stem cells as a source of replacement for lost retinal cells. However a theory has emerged suggesting that stem cells can act through the secretion of signalling molecules (growth factors). One stem cell that has recently shown great promise for neuronal repair are dental pulp stem cells (DPSC), which are multipotent stem cells easily isolated from adult teeth, including third molars (Mead et al 2013, 2014).
In our research, we transplanted either dental pulp stem cells or the more widely studied bone marrow-derived mesenchymal stem cell (BMSC) into the vitreous chamber of the eye after optic nerve crush (Mead et al 2013). The main finding of this study was that DPSC, to a significantly greater degree than BMSC, promoted the survival of injured RGC and the regeneration of their axons. We also showed that the mechanism of action was not through differentiation and replacement of cells but was actually paracrine mediated, i.e. through DPSC-derived growth factors (Mead et al, 2013, 2014).
(more…)
MedicalResearch.com Interview with: Reed Jost, MS
Retina Foundation of the Southwest
9600 N Central Expwy, Suite 200
Dallas, TX 75231
MedicalResearch: What are the main findings of the study?Answer: Commercially available automated screening devices assess refractive risk factors, not amblyopia or strabismus, resulting in under-referral of affected children and over-referral of healthy children to pediatric eye care professionals. The Pediatric Vision Scanner is a binocular retinal birefringence scanner that directly detects strabismus and amblyopia by analyzing binocular scans for the presence or absence of birefringence, which is characteristic of steady, bifoveal fixation. We found that the Pediatric Vision Scanner outperformed an automated, refractive error screener (SureSight Autorefractor) in a cohort of 300 patients (2-6 years) tested in a pediatric ophthalmology setting. Compared to the SureSight, the Pediatric Vision Scanner had significantly higher sensitivity and higher specificity in the detection of strabismus and amblyopia. (more…)
MedicalResearch.com Interview with: Michael Wall, MD
Department of Neurology,
University of Iowa Hospitals and Clinics, 200 Hawkins D
Iowa City, IA 52242-1091
MedicalResearch.com: What are the main findings of the study?Dr. Wall: We studied patients with idiopathic intracranial hypertension (formerly called pseudotumor cerebri) with mild visual loss. We found that subjects taking acetazolamide, a type of diuretic, along with a low sodium weight loss program had significantly better visual outcomes than those taking placebo along with the diet.
(more…)
MedicalResearch.com Interview with: Massimo Porta, MD PhD
Professor of Medicine Head, Unit of Internal Medicine 1
Department of Medical Sciences University of Turin
MedicalResearch.com: What are the main findings of the study?Dr. Porta: Type 2 diabetes has a slow, insidious onset and may remain undiagnosed for several years, during which complications may arise and progress. As a result, many patients already have retinopathy at the time a clinical diagnosis is finally made. Previous attempts at estimating the duration of this period of "hidden" diabetes relied upon extrapolations of a linear correlation between known duration of diabetes and prevalence of retinopathy.
This led to overestimates, because:
a) the best fitting correlation may not be linear,
b) series included insulin treated patients, who might have late-onset type 1 diabetes,
c) patients with any mild retinopathy were included whereas we now know that up to 10% of non diabetic individuals may have minimal retinal signs.
By taking these variables into account, ie including only patients not on insulin and with moderate or more severe retinopathy and applying different mathematical models, we ended up with an estimated duration preceding diagnosis of type 2 diabetes of 4-6 years, against longer than 13 years using "standard" criteria.
(more…)
MedicalResearch.com Interview with:Chung-Jung Chiu DDS PhD
Scientist II, JM USDA Human Nutrition Research Center on Aging
Assistant Professor, School of Medicine
Tufts University Boston MA 02111
MedicalResearch.com: What are the main findings of the study?Answer: In this study, we found that advanced age-related macular
degeneration (AMD) is predictable by using clinically readily available
information. We devised a simple algorithm to summarize the clinical
predictors and showed the validity of our prediction model in both
clinic-based and community-based cohorts. We also develop an
application (App) for the iPhone and iPad as a practical tool for our
prediction model.
(more…)
MedicalResearch.com Interview with:Glenn Yiu, MD, PhD
Duke Ophthalmology
Duke University Medical Center
MedicalResearch.com: What are the main findings of the study?Dr. Yiu:This paper reported a child who suffered injury to both eyes from a powerful blue laser pointer purchased via the internet from overseas. Our report reviews the scientific basis for laser injuries in eyes and the factors that may affect outcomes, such as power, wavelength, duration, and distance of exposure. Newer green and blue lasers, especially high-powered ones, may be more prone to inducing eye injuries. We summarized the clinical features of ocular laser injuries, methods of prevention, and discussed how consumer availability of high powered lasers may require careful federal regulations.
(more…)
MedicalResearch.com Interview with:Maria Lorenza Muiesan
Department of Clinical and Experimental Sciences
University of Brescia, Internal Medicine
Brescia, Italy.
MedicalResearch.com: What are the main findings of the study?Dr. Muisean: An increase in the ratio of retinal arteries wall thickness to lumen diameter may serve as an in-vivo parameter of microvascular damage. We conducted a study that examined the relationship between changes in retinal arterioles wall thickness/ lumen diameter and several measures of blood pressure, including clinic brachial blood pressure, 24 hours brachial blood pressure and central aortic blood pressure. We found that the an increase of wall-to-lumen ratio of retinal arterioles was most closely related to 24 hours blood pressure.
(more…)
MedicalResearch.com Interview with: Dr. Flora Lum, MD
Executive Director, The H. Dunbar Hoskins Jr., M.D. Center for Quality Eye Care,
American Academy of Ophthalmology
San Francisco, CA 94109-1336
MedicalResearch.com: What are the main findings of the study? Dr. Lum: This study anticipates the increased use of claims data for research.
The study recommends a checklist for authors to use in reporting claims data analyses, and discusses the advantages and limitations of using claims data.
MedicalResearch.com: Were any of the findings unexpected? Dr. Lum: There is variability in the methods and descriptions of claims data analyses, and as these increase in number and importance, its encouraged that researchers use rigorous methods.
(more…)
MedicalResearch.com Interview with:Jie Jin Wang MMed (Clin Epi) MAppStat PhD
Professor Australian NHMRC Senior Research Fellow (Level B)
Centre for Vision Research
Westmead Millennium Institute University of Sydney C24
Westmead Hospital, NSW 2145 Australia
MedicalResearch.com: What are the main findings of the study?Answer: We documented a consistent association between high dietary intake of lutein/zeaxanthin (LZ) and a reduced long-term risk of early age-related macular degeneration (AMD) in persons who carry ≥2 risk alleles of either or both the complement factor H (CFH-rs1061170) and/or the age-related maculopathy susceptibility gene 2 (ARMS2-rs10490924)in two older population-based cohorts.
(more…)
MedicalResearch.com Interview with:Dr. Eelco van Duinkerken
Vrije Universiteit Medical Center, Amsterdama
MedicalResearch.com: What are the main findings of the study?Answer: In our study we assessed the relationship between cerebral small vessel disease and peripheral microvascular function in type 1 diabetes patients. By MRI cerebral small vessel disease was assessed as white matter hyperintensities and lacunar infarcts (markers of ischemia) and cerebral microbleeds (expression of vascular leakage). We hypothesized that subgroups, i.e. those with (proliferative) retinopathy, are more at risk to develop cerebral small vessels disease. To this end, we selected type 1 diabetes patients with proliferative retinopathy, type 1 diabetes patients without microvascular complications and healthy controls. The main finding of our study was that only cerebral microbleeds, but not ischemic markers of cerebral small vessel disease were more prevalent in type 1 diabetes patients with proliferative retinopathy relative to the other groups. Cerebral microbleeds were also related to microvascular function in skin. This suggest that cerebral microbleeds are part of generalized microangiopathy in patients with type 1 diabetes.
(more…)
MedicalResearch.com Interview with: Birgitta Ejdervik Lindblad, MD PhD
Department of Ophthalmology
Örebro University Hospital Örebro, Sweden
MedicalResearch.com: What are the main findings of the study?
Answer: We have investigated the association between smoking cessation and risk of having a cataract extraction among 44 371 Swedish men aged 45-79 years. During 12 years of follow up we identified 5713 incident cases of cataract extraction.
Smoking cessation significantly decreased the risk with time.
Men who currently smoked more than 15 cigarettes per day had a 42 % increased risk of cataract extraction compared with men who had never smoked.
More than 20 years since quitting smoking, men who had smoked more than 15 cigarettes per day had a 21% increased risk of having a cataract extraction compared with men who had never smoked.
The effect of smoking cessation was observed earlier among men who smoked less than 15 cigarettes per day but more than 2 decades since smoking cessation the risk had not decreased to the level of never smokers.
(more…)
[caption id="attachment_48090" align="alignleft" width="150"] Dr. Chew[/caption]
MedicalResearch.com Interview
Emily Y. Chew, M.D.
Deputy Director, Division of Epidemiology and Clinical Applications
National Eye Institute
National...
MedicalResearch.com Interview with:Dr. Jerry Y. Niederkorn, Ph.D.
George A. and Nancy P. Shutt
Professorship in Medical Sciences
Royal C. Miller Chair in Age-Related Macular Degeneration Research Professor of Ophthalmology and Microbiology
Vice Chair, Research (Department of Ophthalmology)
Department of Ophthalmology, University of Texas Southwestern Medical Center
Dallas, TX
FN-γ Blocks CD4+CD25+ Tregs and Abolishes Immune Privilege of Minor Histocompatibility Mismatched Corneal Allografts
MedicalResearch.com: What are the main findings of the study?Dr. Niederkorn: These findings indicate that a combination of two simple maneuvers increases the acceptance of corneal transplants. In the past, there was no clear benefit in performing tissue matching of the cornea donor’s major histocompatibility complex (MHC) with the recipient of the corneal transplant. However, our study in experimental animals revealed that blocking a single immune system molecule called interferon-gamma (IFN-γ) combined with matching the corneal transplant donor with the transplant recipient’s MHC gene complex reduced the risk of rejection to less than 10% in the total absence of anti-rejection drugs. This study revealed that blocking this single immune system molecule promoted the development of immune system cells called T regulatory cells (Tregs) that suppressed the lymphocytes that are responsible for attacking organ transplants.
(more…)
MedicalResearch.com Interview with: Dr. Yang Liu
Preceptor and
Dr. David A. Sullivan, MS, PhD, FARVO
Senior Scientist, Schepens Eye Research Institute, Associate Professor, Department of Ophthalmology Harvard Medical School
Boston, MA, USA 02114
MedicalResearch.com: What is the main finding of the study?Answer:We discovered that azithromycin (AZM) can directly stimulate the function of human meibomian gland epithelial cells. Given this finding, it is possible that this antibiotic may prove beneficial as a treatment for meibomian gland dysfunction (MGD), which is the leading cause of dry eye disease in the world.
(more…)
MedicalResearch.com Interview with:Fu-Shin X. Yu, Ph.D.
Professor and Director of Research
Kresge Eye Institute/Department of Ophthalmology
Wayne State University School of Medicine
Detroit, MI 48201
MedicalResearch.com: What are the main results of your study?
Dr. Fu-Shin X. Yu: Using genome-wide cDNA array, we identified a large group of gene differentially expressed in healing corneal cells of diabetes mellitus, when compared to normoglycemia, corneas.
Gene ontology analysis suggests transforming growth factor (TGFβ) signaling as a major signaling pathway affected by hyperglycemia in diabetes mellitus corneal epithelial cells.
(more…)
MedicalResearch.com Interview with: Jelle Vehof PhD
Department of Twin Research & Genetic Epidemiology
King’s College London, St Thomas’ Hospital, Waterloo, London, England
Department of Ophthalmology & Epidemiology
University Medical Center Groningen, Groningen, the Netherlands
MedicalResearch.com: What are the main findings of the study?Dr. Vehof: The current study provides the first empirical evidence that individuals with dry eye disease show altered pain sensitivity. Specifically, this study demonstrates that subjects with DED pain and discomfort complaints have lower pain threshold and pain tolerance of heat-based stimulus compared to those without.
These findings support the hypothesis that a subset of persons with DED is more sensitive to pain.
(more…)
MedicalResearch.com Interview with: Chiu-Fang Chou DrPH
Division of Diabetes Translation National Center for Chronic Disease Prevention and Health Promotion CDC, 4770 Buford Hwy, NE (K-10)
Atlanta GA 30341-3727
MedicalResearch.com: What are the main findings of the study?A: We estimated nearly 9 million people aged 40 years and older are visually impaired using the National Health and Nutrition Examination Survey. Three out of every four people aged 40 years and older with VI have uncorrected refractive error that could be easily corrected with simple glasses or contact lenses. The ocular disease most associated with visual impairment in our study sample was age-related macular degeneration. Finally, increasing age and low educational attainment were significant predictors of visual impairment.
(more…)
MedicalResearch.com Interview with: Michael Belkin, MA, MD
Professor of Ophthalmology
Director, Ophthalmic Technologies Laboratory
Goldschleger Eye Research Institute
Tel Aviv University
Sheba Medical Center Tel Hashomer 52621
Israel
MedicalResearch.com: What are the main findings of the study?Dr. Belkin: Modern ophthalmic treatment, when freely availableis able to reduce the incidence of blindness, and presumably visual impairment considerably. In Israel the rate of new cases of blindness per 100.000 people [age adjusted] was reduced between 1999 and 2010 from 33.8 to 14.8, i.e., by over 56%. The reduction was in all major causes of blindness, Age-related Macular Degeneration (AMD), Glaucoma, Diabetic Retinopathy and Cataract. In the non-treatable retinal dystrophies such as retinitis pigmentosa, there was no significant changes over this period.
(more…)
Department of Psychology & Neuroscience,
Institute for Genome Sciences & Policy
2020 West Main Street, Suite 201
Box 104410
Durham, North Carolina 27708
TITLE:Retinal Vessel Caliber and Lifelong Neuropsychological Functioning
An international research team from the USA, UK, Singapore and New Zealand reports that the size of the blood vessels in the back of the eye can indicate the health of the brain of people approaching midlife (age 38 years), years before age-related declines in brain functioning.
PUBLICATION SOURCE: Psychological Science, advance online publication date, May 2013. BACKGROUND:
Young people who score low on IQ tests, tend to be at higher risk for diseases in later life, and even tend to die younger.
One plausible explanation for this link is that intelligence tests assess brain health.
Digital retinal imaging is a relatively new and non-invasive method to visualize the small blood vessels in the retina, at the back of the eye. The small vessels in the eye may reflect the conditions of the vessels inside the brain because both eye and brain vessels share similar size, structure and function. Thus, retinal imaging can provide a window to study the health of the brain in living humans.
We studied the link between retinal vessel width and intelligence tests scores in the representative Dunedin birth cohort of 1000 New Zealanders born in 1972-73, and followed for 38 years with repeated assessments.
Using a digital fundus camera, which can photograph the interior surface of the eye, we were able to assess the size of the small blood-vessels in the retina, namely, the arterioles and venules (the small branches of the arteries and veins). We also administered intelligence tests in childhood and adulthood.
THE FINDING:
We found that study members who presented with wider venules had poorer intelligence tests scores at midlife (age 38 years). This finding held up independently of potential factors that may explain this link, such as low socio-economic status, smoking, or diabetes.
Moreover, wider venules in the eye were linked with lower childhood IQ that had been tested 25 years earlier.
MedicalResearch.com eInterview with:Emily Y. Chew, MD
Division of Epidemiology and Clinical Applications
National Eye Institute (NEI)/National Institutes of Health (NIH),
Bethesda, Maryland
MedicalResearch.com: What are the main findings of the study? Dr. Chew: For patients who have intermediate age-related macular degeneration (AMD) or those with advanced AMD in one eye, we have recommended a mixture of vitamins and minerals (vitamin C, E and beta-carotene, and zinc oxide and cupric oxide), known as Age-Related Eye Disease Study (AREDS) formulation. We tested the effects of adding carotenoids, lutein/zeaxanthin, or omega-3 fatty acids or both to the AREDS formulation. Omega-3 fatty acids did not have any effect on AMD. Addition of lutein/zeaxanthin provided an additional 10% increase in the reduction of progression to advanced AMD. In persons with the lowest dietary intake of lutein/zeaxanthin, supplementation with lutein/zeaxanthin provided 25% reduction in rates of developing advanced AMD When we tested lutein/zeaxanthin directly against beta-carotene, the risk of progressing to advanced AMD was reduced by 20%. Furthermore, beta-carotene was found to increase the risk of lung cancer. To improve the safety and efficacy of the AREDS formulation, we would suggest the elimination of beta-carotene and adding lutein/zeaxanthin. Omega-3 fatty acids added no further benefit.
(more…)
This website uses cookies to improve your experience. We'll assume you're ok with this, but you can opt-out if you wish.AcceptRejectRead More
Privacy & Cookies Policy
Privacy Overview
This website uses cookies to improve your experience while you navigate through the website. Out of these cookies, the cookies that are categorized as necessary are stored on your browser as they are as essential for the working of basic functionalities of the website. We also use third-party cookies that help us analyze and understand how you use this website. These cookies will be stored in your browser only with your consent. You also have the option to opt-out of these cookies. But opting out of some of these cookies may have an effect on your browsing experience.
Necessary cookies are absolutely essential for the website to function properly. This category only includes cookies that ensures basic functionalities and security features of the website. These cookies do not store any personal information.
MedicalResearch.com Interview with:
Dr. David O'Brart
Keratoconus Research Institute, Department of Ophthalmology
St. Thomas' Hospital, London, United Kingdom
Medical Research: What are the main findings of the study?
Dr. O'Brart: There was a slight but significant increase in myopic spherical equivalent refractive error after Photorefractive Keratectomy between 1 and 20 years, particularly in those under 40 at the time of treatment and female patients.
Corneal curvature/power remained unchanged but axial length increased over two decades. The procedure was safe with no long-term sight-threatening complications and improvements in CDVA (corrected distance visual acuity) and corneal transparency with time.
(more…)
