Author Interviews, Environmental Risks, Pediatrics, Toxin Research, Weight Research / 08.03.2021
Lead Exposure During Pregnancy Associated with Reduced Kidney Function in Overweight Adulthood
MedicalResearch.com Interview with:
[caption id="attachment_56864" align="alignleft" width="130"]
Dr. Sanders[/caption]
Alison P. Sanders, PhD
Pronouns: She/Her
Assistant Professor
Icahn School of Medicine at Mount Sinai
Department of Environmental Medicine and Public Health
Department of Pediatrics
Director, Interdisciplinary Environmental Health Postdoctoral Fellowship
MedicalResearch.com: What is the background for this study?
Response: My research group is dedicated to understanding environmental and early life risk factors that contribute to kidney function decline. While some of the pathobiology leading to chronic kidney disease remains unclear, we understand that the process is complex and, like many chronic diseases, begins long before clinical diagnosis. My research investigates how the environment and mixtures of environmental chemicals/toxicants interact with traditional risk factors such as obesity, preterm birth, and nutritional status to hasten or prevent chronic kidney disease.
Dr. Sanders[/caption]
Alison P. Sanders, PhD
Pronouns: She/Her
Assistant Professor
Icahn School of Medicine at Mount Sinai
Department of Environmental Medicine and Public Health
Department of Pediatrics
Director, Interdisciplinary Environmental Health Postdoctoral Fellowship
MedicalResearch.com: What is the background for this study?
Response: My research group is dedicated to understanding environmental and early life risk factors that contribute to kidney function decline. While some of the pathobiology leading to chronic kidney disease remains unclear, we understand that the process is complex and, like many chronic diseases, begins long before clinical diagnosis. My research investigates how the environment and mixtures of environmental chemicals/toxicants interact with traditional risk factors such as obesity, preterm birth, and nutritional status to hasten or prevent chronic kidney disease.


Dr. Janey Pratt, MD
Clinical Associate Professor, Surgery
Stanford University
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: In 2013 obesity became recognized as a disease. The rate of pediatric obesity continues to rise. Severe pediatric obesity is rising at a even faster rate than obesity in pediatrics. Despite this Metabolic and Bariatric Surgery (MBS) remains underutilized in the treatment of severe pediatric obesity. There is a significant amount of adult data and now pediatric data about effective treatments for severe obesity. These support the use of MBS as a primary treatment for severe obesity in children. (BMI > 120% of 95th percentile with a comorbidity or BMI > 140% of 95th percentile).








