sleep apnea Tag
08 Aug No Close Link Between Cancer and Obstructive Sleep Apnea
MedicalResearch.com Interview with:
Dr. Tetyana Kendzerska
Institute for Clinical Evaluative Science
Women's College Research Institute
Women's College Hospital
Department of Medicine
University of Toronto
Medical Research: What are the main findings of the study?
Dr. Kendzerska: In a large cohort with varying degrees of obstructive sleep apnea (OSA), severity of obstructive sleep apnea was not found to be independently associated with either prevalent or incident cancer, except in one subgroup analysis in smoking-related cancer.
13 Jun Obstructive Sleep Apnea: Obesity, Sleep Apnea and Hypertension Linked
Posted at 10:46h
in Author Interviews, NEJM, Obstructive Sleep Apnea, University of Pennsylvania, Weight Research
MedicalResearch.com Interview with:
Julio A. Chirinos, MD, PhD
Assistant Professor of Medicine
Director, CTRC Cardiovascular Phenotyping Unit
Perelman School of Medicine, University of Pennsylvania
Director of Non-Invasive Imaging
Philadelphia VA Medical Center
MedicalResearch: What are the main findings of the study?
Dr. Chirinos: The main findings of the study is that, among patients with obesity and moderate to severe obstructive sleep apnea, obesity, rather than OSA, appears to be the primary cause of inflammation, insulin resistance and dyslipidemia. However, both obesity and obstructive sleep apnea appear to be causally related to hypertension. In this population, weight loss, but not CPAP, can be expected to reduce the burden of inflammation, insulin resistance and dyslipidemia. However, CPAP, among patients who comply with therapy, can be expected to provide a significant incremental benefit on blood pressure. The latter is an important potential benefit of CPAP and should not be disregarded.
11 Jun Obstructive Sleep Apnea May Increase Risk of Diabetes
MedicalResearch.com Interview with:
Tetyana Kendzerska MD, PhD
Postdoctoral Fellow
Institute for Clinical Evaluative Science,
Sunnybrook Health Sciences Center, Toronto, ON
MedicalResearch: What are the main findings of the study?
Dr. Kendzerska: Based on a large sample of more than 8,500 participants with suspected sleep apnea, our study shows that among people with obstructive sleep apnea (OSA), and controlling for risk factors for diabetes development, initial OSA severity predicted risk for incident diabetes. Measures of the physiologic consequences of OSA (e.g., low level of oxygen, sleep deprivation) were also risk factors for diabetes in this population.
16 Apr Obstructive Sleep Apnea Raises Risk of Osteoporosis
MedicalResearch.com Interview with:
Kai-Jen Tien, MD
Division of Endocrinology and Metabolism,
Department of Internal Medicine, Chi Mei Medical Center
Assistant Professor, Center of General Education
Chia Nan University of Pharmacy and Science
Tainan, Taiwan
MedicalResearch.com: What are the main findings of the study?
Answer: We conducted the first and largest population-based cohort study to evaluate the association of obstructive sleep apnea (OSA) and osteoporosis in a 6-year follow-up investigation of an Asian population. OSA is characterized by repetitive episodes of apnea/hypopnea and hypoxia in tissue, which might impact the bone metabolism. The results of the study showed that patients with obstructive sleep apnea had 2.74 times the risk of osteoporosis than patents without obstructive sleep apnea after adjustment for the patient`s characteristics and comorbidities. Across all age groups and sex groups, individuals with OSA had higher incidence rate of osteoporosis than individuals without obstructive sleep apnea. Subgroup analysis showed that older patients and female patients had a higher risk for osteoporosis than their younger and male counterparts.
03 Mar Pneumonia Risk Increased From Sleep Apnea
MedicalResearch.com Interview with:
Dr. Vincent Yi-Fong Su
Department of Chest Medicine
Taipei Veterans General Hospital
Taipei, Taiwan
MedicalResearch.com: What are the main findings of the study?
Answer: We found interestingly that patients with sleep apnea experienced a 1.20-fold (95% CI, 1.10-1.31; p <0.001) increase in incident pneumonia compared to patients without sleep apnea. We also demonstrated an “exposure-response relationship,” in that the patients with more severe sleep apnea might have a higher risk for pneumonia than did those of milder severity.
10 Feb Childhood Obstructive Sleep Apnea and Anti-Inflammatory Treatment
MedicalResearch.com Interview with:
David Gozal, MD
The Herbert T. Abelson Professor and Chair
Department of Pediatrics
Physician-in-Chief, Comer Children's Hospital
The University of Chicago Chicago, IL 60637
MedicalResearch.com: What are the main findings of the study?
Dr. Gozal: Our study shows that in children with mild obstructive apnea, treatment with an anti-inflammatory combination of 2 medications, namely nasal corticosteroid and oral montelukast is associated with favorable outcomes in the vast majority of the children. Thus, rather than pursue treatment with adenotonsillectomy as is currently the case in most places, this study paves the way for non-surgical alternative therapies in pediatric OSA.
02 Jan Obstructive Sleep Apnea: Outcomes in Hospitalized Pneumonia Patients
MedicalResearch.com Interview Invitation with:
Dr. Peter Lindenauer MD MS
Director, Center for Quality of Care Research
Baystate Medical Center, Springfield, MA, US
MedicalResearch.com: What are the main findings of the study?
Answer: Among a cohort of 250,000 patients hospitalized for pneumonia at 347 US hospitals, those with a diagnosis of obstructive sleep apnea were twice as likely to be intubated at the time of hospital admission than patients without sleep apnea. In addition, patients with sleep apnea had approximately 50% higher risk of needing to be transferred to the ICU after initial admission to a regular bed, and a 70% increased risk of requiring intubation later in the hospital stay. Patients with sleep apnea stayed longer in the hospital and incurred higher costs than those without sleep apnea.
21 Dec Obstructive Sleep Apnea: Value of Being Elbowed by Bed-Partner
MedicalResearch.com Interview Invitation M.E. Fenton MD MSc FRCPC FCCP Associate Professor Program Director, Respirology Training Program Division of Respirology, Critical Care and Sleep Medicine University of Saskatchewan MedicalResearch.com: What are the main findings of the study? Dr. Fenton: This study demonstrates that asking a simple question in the outpatient clinic – Does your bed-partner ever poke or...
16 Dec Blood Pressure: Effect of CPAP in Patients with Obstructive Sleep Apnea
MedicalResearch.com Interview with: Dr. Miguel-Ángel Martínez-García Respiratory Department, Hospital Universitario y Politécnico La Fe Valencia, Spain MedicalResearch.com: What are the main findings of this study: Answer: The main findings of the study are: 1. The treatment with CPAP (continuous positive airway pressure) achieves a clinically and statistically significant reduction of blood pressure in patients with resistant hypertension (blood pressure that remains above goal in spite of the use of at least three antihypertensive drugs) and obstructive sleep apnea.15 Nov Obstructive Sleep Apnea: Gender-Specific Adiposity and Metabolic Syndrome
MedicalResearch.com Interview with: MedicalResearch.com Interview with: Dr. Emilia Mazzuca Biomedical Department of Internal and Specialistic Medicine (DIBIMIS) Section of Pneumology and Dr. Maria R Bonsignore, MD Associate Professor in Respiratory Medicine University of Palermo, Palermo, Italy MedicalResearch.com: What are the main findings of the study? Answer: Our main goal was to investigate gender-related interactions between obstructive sleep apnea (OSA) and obesity while taking associated metabolic abnormalities into account. We analyzed 423 men and 105 women previously studied for the association of OSA and the Metabolic Syndrome (MetS) (Bonsignore et al, Eur Respir J, 2012), to assess whether markers of general and visceral obesity were differently associated with OSA in men and women. Multivariate analysis showed that in men the apnea-hypopnea index (AHI), an indicator of OSA severity, was associated with waist circumference, a marker of visceral obesity, and body mass index (BMI); conversely, in women AHI was associated with hip circumference, a marker of subcutaneous fat deposition, and neck size. The results were similar when patients without a diagnosis of MetS were analyzed; conversely, in patients with MetS, waist circumference was the only significant marker of OSA in both genders.10 Oct Sleep Apnea: Effect of CPAP on Blood Pressure
Posted at 16:34h
in General Medicine
MedicalResearch.com Interview with:
Cristiano Fava MD, PhD
University of Verona
Department of Medicine
Division of Internal Medicine C
Hospital “Policlinico G.B. Rossi”
37134 Verona Italy
University of Lund
Department of Clinical Sciences
Division of Endocrinology
CRC, Lund University
S-205 02 Malmö Sweden
MedicalResearch.com: What are the main findings of the study?
Dr. Fava: The main finding of the meta-analysis is that cPAP usage for at least 2 weeks, with respect to either placebo or usual care is associated with a significant reduction in both systolic and diastolic blood pressure. However the effect size of blood pressure reduction is modest.
21 Sep Sleep Apnea: CPAP Treatment and Golf Performance
MedicalResearch.com Interview with: Marc L. Benton, MD, FCCP, FAASM Morristown Medical Center and Atlantic Sleep & Pulmonary Associates, 300 Madison Ave. Third Floor Madison, NJ 07940 MedicalResearch.com: What are the main findings of the study? Dr. Benton: When compared to a group of matched controls, 12 male golfers who had moderate-severe obstructive sleep apnea syndrome (OSAS) demonstrated statistically significant improvement in their ability to play golf (as measured by changes in the Handicap Index, the standardized indicator of golfing performance) after undergoing CPAP treatment for their condition. Treatment adherence among the group placed on CPAP was unusually high.22 Aug Gestational Diabetes Mellitus and Sleep Apnea
Posted at 01:59h
in Author Interviews, Diabetes, JCEM, OBGYNE, Obstructive Sleep Apnea, Sleep Disorders
MedicalResearch.com: Interview with
Sirimon Reutrakul MD
Section of Endocrinology Department of Medicine
Rush University Medical Center
Chicago, Illinois 60612
MedicalResearch.com: What are the main findings of the study?
Answer: We found a strong association between obstructive sleep apnea and gestational diabetes mellitus. In pregnant women diagnosed with gestational diabetes, the risk of obstructive sleep apnea is increased nearly 7-fold compared to those without gestational diabetes. In addition, we found that in non-diabetic women, pregnancy is associated with more disrupted sleep.
26 Mar Independent associations between fatty acids and sleep quality among obese patients with obstructive sleep apnoea syndrome.
MedicalResearch.com Interview with Dr. Christopher Papandreou Department of Social Medicine, Preventive Medicine and Nutrition Clinic, Medical School, University of Crete, Heraklion, Greece. MedicalResearch.com: What are the main findings of the study? Dr. Papandreou: Certain adipose tissue fatty acids measured in the gluteal site were found to be associated with sleep quality parameters in obese patients with obstructive sleep apnoea syndrome after controlling for possible confounders.04 Aug Compression Stockings May Reduce Sleep Apnea in Some Patients
Posted at 23:36h
in Sleep Disorders
August 4 2011 Newswise — Wearing compression stockings may be a simple low-tech way to improve obstructive sleep apnea in patients with chronic venous insufficiency, according to French researchers. ”We found that in patients with chronic venous insufficiency, compression stockings reduced daytime fluid accumulation in the legs, which in turn reduced the...
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