Author Interviews, Inflammation, Nutrition, Vitamin K / 25.03.2014

MedicalResearch.com Interview with Mònica Bulló PhD Human Nutrition Unit Department of Biochemistry & Biotechnology IISPV  School of Medicine Rovira i Virgili University Sant Llorenç, Spain MedicalResearch.com: What are the main findings of the study? Dr Bulló: There is some evidence that different dietary forms of vitamin K could exert varying effects on health, however no study to date has simultaneously evaluated the potential effects of the main vitamin K forms on cancer and cardiovascular mortality. We conducted a prospective, epidemiologic study involving 7,216 elderly subjects at high cardiovascular risk who were followed for about 5 years.The results of the present study show, for the first time that an increase in dietary intake of both forms of vitamin K is related to a lower risk of cardiovascular mortality, cancer mortality or all-cause mortality.
Author Interviews, Inflammation, JAMA, Mental Health Research, PTSD / 12.03.2014

Dr. Dewleen Baker MD Veterans Affairs (VA) San Diego Healthcare System, San Diego, California MedicalResearch.com Interview with: Dr. Dewleen Baker MD Veterans Affairs (VA) San Diego Healthcare System, San Diego, California MedicalResearch.com: What are the main findings of the study? Dr. Baker: The main finding of this study is that a marker of peripheral inflammation, plasma CRP may be prospectively associated with PTSD symptom emergence, suggesting that inflammation may predispose to PTSD.
Aging, CMAJ, Inflammation / 18.09.2013

MedicalResearch.com Interview with: Tasnime Akbaraly  PhD Institut National de la Santé et de la Recherche Médicale Montpellier, France MedicalResearch.com: What are the main findings of the study? Dr. Akbaraly: The aim of this study was to examine the association between chronic inflammation and a range of aging phenotypes, assessed approximately 10 years later in a large British population of men and women  -The Whitehall II Study-. As inflammation characterises a wide range of pathological processes, we considered several aging phenotypes, including cardiovascular disease (fatal and non-fatal), non-cardiovascular mortality and successful aging which encompasses optimal functioning across different physical, mental, and cognitive domains We found that chronic inflammation characterized by high levels of interleukin-6 (>2 pg/mL) twice over the 5-year exposure period nearly halved the odds of successful aging after 10–years of follow-up compared to maintaining low levels of interleukin-6 (<1pg/mL twice over the exposure period). Chronic inflammation was also associated with increased odds of future cardiovascular disease and non-cardiovascular mortality in a dose-response fashion. These associations were found to be independent of socio-economic factors, health behaviours (smoking, physical activity), and conditions such as obesity as well as the use of anti-inflammatory drugs and acute inflammation.