Author Interviews, Cannabis, JAMA, Pediatrics / 07.01.2022

MedicalResearch.com Interview with: Daniel Myran, MD, MPH, CCFP, FRCPC Family and Public Health and Preventive Medicine Physician CIHR Fellow, Ottawa Hospital Research Institute Department of Family Medicine Innovation Fellow University of Ottawa MedicalResearch.com: What is the background for this study? Response: Canada legalized recreational, or non-medical, cannabis in October 2018. Canada took phased approach to legalization initially only allowing flower-based cannabis products and oils and after one year permitting the sale of commercial cannabis edibles (e.g. THC containing candies, baked goods, and drinks). In this study we took advantage of this phased roll out of legal cannabis to understand the impact of legalization on cannabis exposures or poisonings in children aged 0-9 years and the contribution of different types of cannabis products to these events. (more…)
Author Interviews, Cannabis, Neurology, Pediatrics / 15.12.2021

MedicalResearch.com Interview with: Rayyan Raja Zafar BSc. MSc. MRSB. Medical Research Council Doctoral Training Partnership (MRC DTP) PhD Candidate Centre for Psychedelic research & Neuropsychopharmacology Division of Psychiatry Department of Brain Sciences, Faculty of Medicine Professor David Nutt DM, FRCP, FRCPsych, FSB, FMedSci Faculty of Medicine, Department of Brain Sciences The Edmond J Safra Chair in Neuropsychopharmacology Imperial College London MedicalResearch.com: What is the background for this study? Response: Since 2018 medical cannabis prescription has become legal in the UK for patients to access. In spite of this legal change less than 3 NHS prescriptions have been made available and access to whole-plant medical cannabis products has been restricted largely to private prescriptions with very few clinicians prescribing such products. There has been a lot of anecdotal and real world evidence of the value of whole-plant medical cannabis in children suffering with treatment resistant epilepsy. (more…)
Author Interviews, Cannabis, Fertility / 30.11.2021

MedicalResearch.com Interview with: Kanako Hayashi PhD Associate Professor Associate Director, Center for Reproductive Biology Washington State University MedicalResearch.com: What is the background for this study? Response: There have been several correlative reports showing statistical associations between cannabis use and low sperm counts, dysregulated menstruation, abnormal placentation, preterm birth, stillbirth and offspring psychosis etc. However, the long-term consequences of cannabis use on reproductive functions and how it might impact the next generation have not been examined. In the present study, we examined the generational effects of cannabis vapor exposure on male reproductive function. Vaporization is the most common route of cannabis administration in humans. Therefore, in order to understand the generational effects of cannabis exposure on male reproductive functions, the present study was performed using an inhalation method as an administration route, by which adult male mice were exposed to dry cannabis plants to assess the toxicological effects of cannabis on F0, F1 and F2 male reproductive functions. (more…)
Author Interviews, Cannabis, JAMA, Pediatrics / 25.10.2021

MedicalResearch.com Interview with: Carmen Lim BSc(Hons), MSc, CStat PhD Candidate National Centre for Youth Substance Use Research Faculty of Health and Behavioural Sciences The University of Queensland Brisbane Australia MedicalResearch.com: What is the background for this study? What are the main findings? Response: This review has systematically summarized the trends and products used for cannabis vaping using 17 studies published globally between Jan 1, 2003 and August 19, 2020. The pooled prevalence has increased for lifetime use (6.1% in 2013 to 13.6% in 2020), past-year use (7.2% in 2017 to 13.2% in 2020) and past-month use (1.6% in 2013 to 8.4% in 2020). Adolescents' preference for cannabis products may be shifting from less potent products (e.g., herbal cannabis) to highly potent vape oil and concentrates. (more…)
Author Interviews, Cannabis, JAMA / 07.09.2021

MedicalResearch.com Interview with: Mark Anderson, Ph.D. Associate Professor Department of Agricultural Economics and Economics Montana State University, IZA, and NBER  MedicalResearch.com: What is the background for this study? Response: In a previous study that was published in JAMA Pediatrics, we used Youth Risk Behavior Survey (YRBS) data and found that the adoption of recreational marijuana laws (RMLs) was associated with an 8% decrease in the odds of marijuana use among high school students.  This earlier study, however, had pre-legalization and post-legalization data from only 7 states and pre- and post-recreational sales data from only 3 states, calling into question the generalizability of our findings. (more…)
Accidents & Violence, Author Interviews, Cannabis, CMAJ / 06.04.2021

MedicalResearch.com Interview with: Sarah Windle, MPH PhD Student in Epidemiology Department of Epidemiology, Biostatistics, and Occupational Health McGill University (Montréal, Québec, Canada) MedicalResearch.com: What is the background for this study? Response: Concerns have been raised about the potential for increases in impaired driving following the legalization of recreational cannabis use in Canada in October 2018. Data from Statistics Canada suggest that cannabis use in the previous three months increased among adults (15 and older) from 14% before legalization in 2018 to 17% in 2019. Among those users with a driver’s license, 13% reported driving within two hours of cannabis use. While this proportion remained the same before and after legalization, this indicates that the absolute number of individuals who reported driving within two hours of use has increased following legalization (due to an increase in the number of users). (more…)