MedicalResearch.com Interview with: Peter Kokkinos PhD
Veterans Affairs Medical Center, Cardiology Division
Washington, DC 20422
Medical Research: What are the main findings of the study?Dr. Kokkinos:The main finding of the study is that we defined an exercise capacity threshold for each age category (<50; 50-59; 60-69; and ≥70 years of age). The mortality risk increases progressively below this threshold and decreases above it. We then calculated the 5 and 10-year mortality risk for each age category.
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MedicalResearch.com Interview with: Xuemei Sui, MD, MPH, PhD
Assistant Professor, Department of Exercise Science
Division of Health Aspects of Physical Activity
Arnold School of Public Health
University of South Carolina
Columbia, SC 29208
MedicalResearch: What are the main findings of the study?Dr. Sui: In the present study, cancer survivors who reported performing resistance exercise (RE) at least 1 day of the week had a 33% lower risk of all-cause mortality compared with individuals who did not report participation in resistance exercise. Further, there was an inverse relationship between resistance exercise and all-cause mortality in those who were physically active, but not in those who were physically inactive. Although leisure-time physical activity was not associated with a lower risk of all-cause mortality, the present results support the benefits of resistance exercise and physical activity was during cancer survival.
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MedicalResearch.com Interview with David S.H. Lee, Pharm.D., Ph.D.
Assistant Professor
Department of Pharmacy Practice
College of Pharmacy
Oregon State University/Oregon Health and Science University
Portland OR, 97239
MedicalResearch: What are the main findings of the study?Dr. Lee: We found that older men taking a statin were less physically active and had more sedentary behavior. They had about 37 minutes of less moderate exercise per week. For comparison, the American heart Association recommends about 40 minutes of moderate activity 3-4 times per week. We also found that those that started using a statin during the study had the largest drop in physical activity.
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MedicalResearch.com Interview with:
Holger Cramer, PhD
Director of Yoga Research
University of Duisburg-Essen | Faculty of Medicine
Department of Internal and Integrative Medicine
Essen Germany
MedicalResearch: What are the main findings of the study?Dr. Cramer: There is a number of randomized trials available on yoga for asthma. Based on those trials, there is evidence that yoga can improve asthma symptoms, asthma control, and pulmonary function in patients with asthma. However, yoga does not seem to be superior to sham procedures or breathing exercises and generally the evidence was quite weak. Yoga seems to be relatively safe in this patient population.
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MedicalResearch.com Interview with:
Unab I. Khan, M.B.,B.S., M.S.
Assistant Professor of Pediatrics and Family & Social Medicine
Division of Adolescent Medicine
The Children’s Hospital at Montefiore
The Pediatric Hospital for Albert Einstein College of Medicine
Bronx, NY 10467
MedicalResearch: What are the main findings of the study?Dr. Khan: We wanted to find factors that lead to either an increase or decrease in risk of developing cardiovascular disease. We found that in middle aged overweight and obese women, who may not have any medical problems like diabetes, high blood pressure, high cholesterol, an increase in weight over time and the development of any of the conditions stated above, increased the risk of cardiovascular disease significantly.
On the other hand, even moderate physical activity decreased the risk of heart disease, even in the presence of the above stated conditions.(more…)
MedicalResearch.com Interview Professor Kim Bennell
ARC Future Fellow
Department of Physiotherapy
University of Melbourne
Parkville, Vic 3010 Australia
MedicalResearch: What are the main findings of the study?Professor Bennell: In 102 people with painful hip osteoarthritis, we compared a 'real' physical therapy program involving exercise, manual therapy techniques,education and provision of a cane if appropriate to a sham physical therapy treatment that was made to look as though it was real but instead involved turned off ultrasound and gentle application of a hand crème to the hip region. Participants in both groups went to see a physical therapist on 10 occasions over 12 weeks and performed home exercises if in the 'real' physical therapy group or lightly applied the cream at home if in the sham group. Participants were followed for 9 months in total. We found that while both groups showed improvements in pain and physical function, the improvements were similar between the two groups. That is, the real physical therapy program did not show greater benefits over a sham treatment. (more…)
MedicalResearch.com Interview with: Dr Nikola Drca
Department of Cardiology at the Karolinska Institute,
Karolinska University Hospital
Stockholm Sweden
MedicalResearch: What are the main findings of the study?Dr. Nikola Drca: We found that intense physical activity like leisure-time exercise of more than five hours per week at the age of 30 increased the risk of developing atrial fibrillation later in life by 19%. In contrast, moderate-intensity physical activity like walking or bicycling of more than 1 hour per day at older age (age 60) decreased the risk by 13%. (more…)
MedicalResearch Interview with:Monique Francois
Teaching Fellow & Research Assistant at the University of Otago
School of Physical Education, Sport and Exercise Sciences
University of Otago
Dunedin, New Zealand
MedicalResearch: What are the main findings of the study?
Answer: We found that small 'snacks' of interval exercise before the three main meals lowered postprandial blood glucose and contributed to a lower blood glucose across the day. Whereas 30 minutes of continuous moderate exercise before dinner did not lower postprandial blood glucose nor mean glucose levels the exercise day or the following day, compared to exercise snacking.
Six one minute intervals as walking or a combination of walking and resistance 3x per day (before the three main meals) improved glycaemic control in individuals with insulin resistance.
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MedicalResearch.com Interview with:Luisa Soares-Miranda, PhD
Research Center in Physical Activity, Health and Leisure
Faculty of Sport, University of Porto
Rua Dr. Plácido Costa,
Porto PORTUGAL
MedicalResearch: What are the main findings of the study?Dr. Soares-Miranda: Modest physical activity, such as the distance and pace of walking, is important for the heart’s electrical well being of older adults. In our study, older adults that increased their walking pace or distance had a better heart rate variability when compared with those that decreased their walking pace or distance. Our results suggest not only that regular physical activity later in life is beneficial, but also that certain beneficial changes that occur may be reduced when physical activity is reduced. This supports the need to maintain modest physical activity throughout the aging process. Even small increases can lead to a better health, while reducing physical activity has the opposite effect. So, any physical activity is better than none, and more is better. (more…)
MedicalResearch.com Interview with:Lara McKenzie, Ph.D. MA
Associate Professor of Pediatrics
Center for Injury Research and Policy
The Research Institute at Nationwide Children's Hospital
Columbus, Ohio
MedicalResearch.com: What are the main findings of the study?Dr. McKenzie: Our study was the first to compare and describe epidemiological patterns of basketball-related injuries presenting for treatment to emergency departments and to the high school athletic training setting using surveillance data captured from large, nationally representative samples. Specifically, we compared estimated national incidence, rates of injury and body sites injured, and diagnoses. Nationally, an estimated 1,514,957 athletes with basketball-related injuries reported to the emergency department and 1,064,551 presented to the athletic training setting. Patterns of basketball-related injuries presenting to the emergency department differ from those presenting to the high school athletic training setting for treatment, with those presenting to the emergency department being more severe. In general, injuries that could be relatively quickly assessed and more easily diagnosed and treated, such as strains and/or sprains, presented more commonly to the athletic training setting, while injuries that required more extensive diagnostic or treatment procedures, such as fractures, were treated more commonly in the emergency department.
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MedicalResearch.com Interview with:Neeru Jayanthi, MD
Associate Professor
Medical Director, Primary Care Sports Medicine
Loyola University Medical Center study
MedicalResearch.com: What are the main findings of the study?Dr. Jayanthi: We surveyed a cohort of 1,190 athletes ages 7 to 18, including 1,121 for whom insurance status could be determined. Our main findings were:
1. The rate of serious overuse injuries in athletes who come from families that can afford private insurance is 68 percent higher than the rate in lower-income athletes who are on public insurance (Medicaid).
2. Privately insured young athletes are twice as likely as publicly insured athletes to be highly specialized in one sport.
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MedicalResearch.com Interview with:Zoe Michaleff
PhD Student, Musculoskeletal Division
The George Institute for Global Health
Sydney NSW 2000 Australia
MedicalResearch.com: What are the main findings of the study?
Answer: Our study showed that a 30 minute advice session with two phone call follow ups was as effective for chronic whiplash as the comprehensive physiotherapy exercise program in which participants received twenty, one-hour individually-tailored and supervised exercise sessions over a 12-week period. While people's pain and activity improved in both treatment groups, the most important finding is that there were no differences between groups. This finding held true for all outcome measures except for two secondary outcome measures of self rated recovery (global perceived effect) and functional ability (patient specific functional scale) which were in favour of the comprehensive exercise program however the size of these effects were too small to be considered clinically meaningful.
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MedicalResearch.com Interview with:
Teresa Liu-Ambrose, PhD, PT
Associate Professor, Canada Research Chair
Department of Physical Therapy
Aging, Mobility, and Cognitive Neuroscience Laboratory
Vancouver Coastal...
MedicalResearch.com Interview with: David R. Jacobs Jr, PhD
Divisions of Epidemiology
School of Public Health
University of Minnesota, Minneapolis
MedicalResearch.com: What are the main findings of this study?Dr. Jacobs: Vigorous activity is what is well understood to improve cardiorespiratory fitness. People with high fitness are likely (based on this study) to
a) Lose fitness more slowly as they age and
b) To maintain sharper "thinking skills" into late middle age.
I think the message of this study is primarily for the people in the low to mid range of fitness in young adulthood. Thus, of more importance to the general population, if the people with low to moderate fitness simply do things, be engaged in family, job, community, move around, they would be able to do better on a treadmill test such as we used. Because those who lost less fitness over average age 25 to average age 45 had higher thinking skills at age 50, people who start moving around are likely to reap the benefit of less loss of thinking skills by average age 50.
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MedicalResearch.com Interview with: Professor Mathieu Boniol PhD
International Prevention Research Institute
Lyon, France
MedicalResearch.com: What are the main findings of the study?Prof. Boniol:We conducted a meta-analysis of all prospective epidemiological studies
on physical activity and risk of breast cancer. It includes 37 studies,
so covers more than 4 million women among which more than 100,000 breast
cancer were diagnosed. We showed that when comparing the most active
women (about 20% of the population) to least active women (another 20%
of the population), vigorous physical activity reduce the risk of breast
cancer by 11%. And the good news is that this decline is irrespective of
age, BMI, menopausal status, country,... It is also true for the most
aggressive breast cancer (ER-/PR-). However, we also showed that this
decline is not observed for women taking hormonal replacement therapies,
as if these treatments (which are already infamous for poor efficacy and
increasing the risk of breast cancer) would nullify any benefit from
physical activity.
(more…)
MedicalResearch.com Interview with:Michael Nyberg Ph.D.
Post-doc Human Physiology and Exercise Physiology
Integrated Physiology Group
Department of Nutrition, Exercise and Sports,
Faculty of Science, University of Copenhagen and
Jens Bangsbo, Dr. Sci., Ph.D.
Professor of Human Physiology and Exercise Physiology
Head of Integrated Physiology Group, Section of Human Physiology
Head of Copenhagen Centre of Team Sports and Health
Deputy Head of Department, research
Copenhagen Denmark
MedicalResearch.com: What are the main findings of the study?Answer: The main findings of the study were that despite being of similar age, the postmenopausal displayed higher blood pressure and higher blood levels of an early marker of atherosclerosis than women that had not reached menopause. Furthermore, just 12 weeks of floorball training twice a week for one hour improved the women’s conditions and reduced their blood pressure significantly. In addition, there was positive development in levels of substances vital to blood vessel function, including a decrease in the early marker of atherosclerosis.
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MedicalResearch.com Interview with:Dorothy D Dunlop, PhD
Professor, Medicine-Rheumatology
Center for Healthcare Studies - Institute for Public Health and Medicine and Preventive Medicine
Northwestern University Feinberg School of Medicine
MedicalResearch.com: What are the main findings of the study?Dr. Dunlop: We know being active, especially doing moderate activity like taking a brisk walk, is good for health. We know a sedentary lifestyle leads to health problems. What we do not know is whether or not those are two ways of looking at the same question. Does being sedentary like sitting just reflect insufficient activity OR is sedentary time is a separate and distinct risk factor for health problems. Our physical activity research group looked at national US data from the National Health and Nutrition Examination Survey. This is an important study because they monitored physical activity using an accelerometer. We found sedentary behavior such as sitting was its own separate risk factor for disability.
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Medical Research.com Interview with: James Woodcock
Senior Research Associate
UK CRC Centre for Diet and Activity Research
MRC Epidemiology Unit, University of Cambridge
MedicalResearch.com: What are the main findings of the study?Dr. Woodcock: The cycle hire scheme in London has benefited health through increasing physical activity. This reduces risk from a range of diseases including heart disease, type 2 diabetes, and depression. These benefits were at a population level bigger than the harms the cyclists faced from injury risk or air pollution exposure. Looking at the harms air pollution did not make much difference. The injury risk for users of the hire bikes appears to not be higher and may be lower than that for general cycling in the same area. However, the injury risks for general cycling in the cycle hire zone were quite high and benefits for cyclists would be greater if these risks were reduced. When we broke results for general cycling in the area down by age & gender we found two interesting findings. Firstly, that the risks faced by women were higher than for men and so benefits were less clear. Secondly, when we looked at results by age group the trade-off improved very considerably as people got older and for younger people (under 30) there may actually be harms.
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MedicalResearch.com Interview with:Matthew BumanPhD
School of Nutrition and Health Promotion, Arizona State University
Arizona State University, School of Nutrition and Health Promotion
Phoenix, AZ
MedicalResearch.com: What are the main findings of the study?Dr. Buman: We found that that exercise at night (within 4 hours of bedtime) was not associated with poor sleep compared with individuals that did not exercise before bed. However, we also found that morning exercise appears to be associated with optimal sleep quality.
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MedicalResearch.com Interview with:Carsten Juhl, PhD, MPH
Research Physiotherapist
Forskningsenheden for Muskuloskeletal Funktion og Fysioterapi (FoF)
Institut for idræt og biomekanik
Syddansk Universitet
MedicalResearch.com: What are the main findings of the study?Dr. Juhi: The main findings of this study including 48 RCTs with more than 4000 patients were that
[1] exercise therapy programs focusing on a single type of exercise were more efficacious in reducing pain and patient-reported disability than those mixing several types of exercise with different goals within the same session;
[2] the number of supervised sessions enhances the benefits of the aerobic exercise;
[3] exercise focusing on the knee extensor muscle strength only, may increase the benefits of resistance training and
[4] exercise seems to be effective therapy for knee osteoarthritis, regardless of age, sex, BMI, radiographic status or baseline pain.
MedicalResearch.com Interview with:Rebecca Seguin, PhD, CSCS
Cornell University, Division of Nutritional Sciences
Ithaca NY 14853
MedicalResearch.com: What are the main findings of the study?Answer: The main findings of the study are that regardless of demographic factors and physical activity levels, women who spent the most time engaged in sedentary behaviors had higher risk of death and women who spent the least amount of time engaged in sedentary behaviors.
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MedicalResearch.com Interview with: Maike Neuhaus, MPsych
Australian Postgraduate Award PhD Candidate
Cancer Prevention Research Centre
School of Population Health
The University of Queensland
Herston, QLD 4006 Australia
MedicalResearch.com: What are the main findings of the study? Answer:Substantial epidemiological evidence shows that high volumes of sedentary behaviour – simply put too much sitting- are linked to detrimental health outcomes such as overweight and obesity, type 2 diabetes, some cancers, and all-cause mortality. Desk-based office workers typically spend around 75% of their work hours sitting at their desks or in meetings. Furthermore, they are unlikely to compensate for these high volumes of sitting time at work with less sedentary activities outside of work. Office workers are thus a high-risk group and an important target for intervention.
The Stand Up UQ study examined best-practice approaches to reduce excessive sitting in office workers. Three separate groups of administrative office workers from The University of Queensland in Brisbane, Australia, participated in this study: One group received height-adjustable workstations only; another group received the same height-adjustable workstations plus additional individual (e.g. face-to-face coaching) and organisational strategies (e.g. management consultation, staff information session) to reduce workplace sitting; the third group served as control group and maintained their usual work-practice. Results showed that relative to the control group, the group receiving height-adjustable workstations and additional strategies had a three-fold greater reduction in sitting time than the group receiving height-adjustable workstations only. These findings have important practical and financial implications for workplaces targeting sitting time reductions.
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MedicalResearch.com Interview with: Anna-Christina Lauer, MD
Department of Audiology and Phoniatrics
Charité-University Medicine Berlin
Berlin, Germany
MedicalResearch.com: What are the main findings of the study?Dr. Gross: We could show that the injury rates depend on the undergraduate medical training the students attended. This demonstrates that medical
undergraduatue education, especially a hands-on training, is critical in
the prevention of needlestick- and sharps injuries.
Also the use of safety devices has proven to reduce injury rates
significantly.
Given the large size of our study we could not only comfirm that
needlestick and sharps injuries are still a common problem, looking at an
injury rate of about 20% per year, we also learned a lot about the
accident circumstances: Most accidents occur at bedside during
venepuncture and intravenous cannulation. The second most common setting
is the operating room, where suturing and instrument transfers can lead to
injuries.
Since we analyzed official reports and the anonymous surveys at the same
time we could affirm an underreporting rate of more than 50%.
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MedicalResearch.com Interview with:Dr. Merja K. Laine
Department of General Practice and Primary Health Care
University of Helsinki
MedicalResearch.com: What is the background of your study?Answer: We were interesting to know does a top-level sport during young adulthood protect against disturbances in glucose regulation in later life. In Finland, a unique study program including former male elite athletes and their age- and area-matched controls already initiated in 1985. In 2008, we invited those subjects who participated in the study earlier and were still alive.
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MedicalResearch.com Interview with:Ida C. Svege PhD student / Physical Therapist NAR
Norwegian research centre for Active Rehabilitation Department of Orthopaedics, Oslo University Hospital / NIMI / Norwegian School of Sports Sciences
MedicalResearch.com: What are the main findings of the study?Answer: The main finding of the study was that exercise therapy in addition to patient education resulted in significantly higher 6-year cumulative survival of the native hip to total hip replacement compared with patient education only. Over the 6 year follow-up period the need for total hip replacement was reduced by 44% in the group who received both exercise therpay and patient education. Also, better self-reported physical function was demonstrated in the group who received exercise therapy and patient education, suggesting that the lower surgery rate in this group were due to better hip function, with or without the presence of pain.
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MedicalResearch.com Interview with:Elin Ekblom Bak | Doktorand
Institutionen för Medicin, Enheten för klinisk epidemiologi,
Karolinska universitetssjukhuset Solna
114 86 Stockholm
MedicalResearch.com: What are the main findings of the study?
Answer: That we, in a large sample of 60 y old men and women, found that a generally active day life (compared with an inactive daily life) was significantly associated with a better metabolic health at baseline, and a reduced risk with 27% for a first time cardiovascular event and 30% for all-cause mortality during 12.5 years of follow up. This was seen regardless of intentional exercise. Why this is important is because the focus is often of just exercise for health benefits and longevity. Exercise is still important, but, as we saw in this study, the activity that we do during the extended hours of daily living is as important and has a significant effect on cardiovascular health and longevity. These results are in a reversed way in line with the detrimental effects of prolonged sitting (regardless exercise habits) now frequently reported in an increasing amount of research studies. This is because sedentary time mainly replaces time in daily activity, and vice versa (daily activity replace time spent sitting).
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MedicalResearch.com Interview with:Chris Fritz BSs
PEZZ Center for Pediatric Endocrinology Zurich, Zurich, Switzerland
MedicalResearch.com: What are the main findings of the study?Answer: Targeted strength training significantly increases daily spontaneous physical activity (PA) behaviour in boys. The less active children showed the greatest increase.
102 healthy school children were randomly placed in two groups. The control group continued three PE classes per week, whereas the intervention group had two out of three PE classes replaced by an individualised strength training program. At baseline there was no difference in anthropometry, body composition and PAEE between the groups. At the end of the training intervention, we found a significant increase of upper and lower body strength in the intervention group in boys and in girls. Boys significantly increased their PA by 10%. Without taking into account the energy expenditure during the strength training, the 10% PAEE increase corresponds to a weekly bike ride of 28 miles for a child of 40 kg body weight. Or in other words, an individualised school based strength training program increases energy expenditure outside the intervention by an equivalent of about 7kg of body fat corresponding to 10kg of chocolate per year.
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MedicalResearch.com Interview with: George Mammen, PhD Candidate
Health & Exercise Psychology Unit
University of Toronto
MedicalResearch.com: What are the main findings of the study?Answer:
25 out of the 30 studies found PA to protect against depression; majority of these were of high methodological quality
Decreasing PA overtime can increase the risk of developing depression; increasing PA overtime can reduce the risk of developing depression
In terms of dosage, the review highlighted studies that showed even low levels, such as 20 mins of walking a day, can prevent the onset of depression. (more…)
MedicalResearch.com Interview with:Christian K. Roberts
Exercise and Metabolic Disease Research Laboratory,
Translational Sciences Section, School of Nursing
University of California, Los Angeles, CA
MedicalResearch.com: How would you best summarize the main findings/results of this study?Answer: Our main finding was that HDL functioned better in its antioxidant role in subjects who participated in resistance exercise training (i.e. weight training) a minimum of 4 days a week, regardless of their weight—one group was lean (BMI <25) and the other overweight/obese (BMI >27) —than those who didn’t exercise (overweight, BMI >27, and untrained). In addition, HDL had similar effectiveness as an antioxidant in the overweight-trained group as in the as lean-trained group. Although indices of weight were associated with dysfunctional HDL, differences in fitness may be a better measure of who has healthier functioning HDL.
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MedicalResearch.com InterviewMa, Wei
Department of Epidemiology and Health Statistics
School of Public Health
Shandong University
Jinan, Shandong Province, 250012 China
MedicalResearch.com: What are the main findings of the study?Answer: The results of this meta-analysis suggested that there was an inverse dose-response association between levels of recreational physical activity and risk of hypertension. Individuals who participated in high levels of recreational physical activity had a 19% lower risk of hypertension than those who didn’t exercise much. In addition, those with moderate levels of recreational physical activity had an 11% lower risk of hypertension.
However, there was no significant association between occupational physical activity and risk of hypertension.
(more…)
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