MedicalResearch Interview with:
Dr. Yan Qu
Qingdao Municipal hospital
Fruits and Vegetables Consumption and Risk of Stroke A Meta-Analysis of Prospective Cohort Studies
MedicalResearch: What are the main findings of the study?
Reply:
First, both fruits and vegetables were found inversely associated with risk of stroke, and the relationships might be linear.
Second, the inverse association of fruits and vegetables consumption with risk of stroke is consistent across subgroup analysis by outcome (stroke incidence and stroke mortality), location where the study was conducted (USA, Europe and Asia), sex (male and female), and stroke subtypes (ischemic and hemorrhagic).
Third, citrus fruits, leafy vegetables and apples/pears were found inversely associated with risk of stroke.
Fourth, very similar results were found in the subgroup analysis by status [yes: 0.78 (0.71-0.86) or no: 0.79 (0.74-0.85)] of adjusting for 6 or more of the 7 covariates (smoking, alcohol, blood pressure/hypertension, serum cholesterol, physical activity, body mass index, ≥3 dietary variables). These findings generally indicated that the association of fruits and vegetables consumption with the reduced
risk of stroke may not be the result of confounding by the known factors.
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