Author Interviews, JNCI, Nutrition, Prostate Cancer / 24.05.2014

Edward Giovannucci, MD, ScD Department of Nutrition Harvard School of Public Health Boston, MAMedicalResearch.com Interview with: Edward Giovannucci, MD, ScD Department of Nutrition Harvard School of Public Health Boston, MA MedicalResearch: What are the main findings of the study? Dr. Giovannucci: In 50,000 men followed over 24 years, we found that those regularly consuming tomato products, which are high in lycopene, had a 30% lower risk of developing lethal prostate cancer. Among men being screened regularly with PSA, the risk reduction from high tomato consumption was 50%. We also examined the prostate cancer tissue and found that higher dietary lycopene intake was associated with less new blood vessel formation, which may help explain why the cancers were less likely to progress. (more…)
Nutrition, Prostate Cancer / 23.05.2014

Assistant Professor Department of Obstetrics & Gynecology Division of Clinical & Epidemiologic Research and Cancer Prevention, Detection and Control Research Program and Department of Surgery Division of Urology Duke University School of Medicine Durham, NC 27710 MedicalResearch.com Interview with: Adriana C. Vidal, Ph. D. Assistant Professor Department of Obstetrics & Gynecology Division of Clinical & Epidemiologic Research and Cancer Prevention, Detection and Control Research Program and Department of Surgery Division of Urology Duke University School of Medicine Durham, NC 27710 MedicalResearch: What are the main findings of the study? Dr. Vidal: Among 430 veterans at the VA Hospital in Durham, N.C., including 156 men with confirmed prostate cancer, we found that men who self-reported a higher intake of carbohydrates were at a reduced risk of both low-grade and high-grade prostate cancer. Moreover, we found that intake of foods with high glycemic index increased total prostate cancer risk in black men. However, a higher fiber intake was associated with reduced risk of high grade prostate cancer. (more…)
Author Interviews, Circadian Rhythm, Gastrointestinal Disease, Sugar / 23.05.2014

Dr. Robin Voigt PhD Department of Internal Medicine Division of Gastroenterology Rush University Medical Center Chicago, IllinoisMedicalResearch.com Interview with: Dr. Robin Voigt PhD Department of Internal Medicine Division of Gastroenterology Rush University Medical Center Chicago, Illinois MedicalResearch: What are the main findings of the study?  Dr. Voigt: We found that chronic circadian rhythm disruption has no effect on the intestinal microbiota when mice are fed a standard chow diet but when combined with a high-fat, high-sugar diet circadian rhythm disruption results in intestinal dysbiosis and an increase in pro-inflammatory bacteria. (more…)
Author Interviews, Diabetes, Diabetologia, Exercise - Fitness, Sugar / 14.05.2014

MedicalResearch Interview with: Monique Francois Teaching Fellow & Research Assistant at the University of Otago School of Physical Education, Sport and Exercise Sciences University of Otago Dunedin, New Zealand MedicalResearch: What are the main findings of the study? Answer: We found that small 'snacks' of interval exercise before the three main meals lowered postprandial blood glucose and contributed to a lower blood glucose across the day. Whereas 30 minutes of continuous moderate exercise before dinner did not lower postprandial blood glucose nor mean glucose levels the exercise day or the following day, compared to exercise snacking. Six one minute intervals as walking or a combination of walking and resistance 3x per day (before the three main meals) improved glycaemic control in individuals with insulin resistance. (more…)
AHA Journals, Author Interviews, Nutrition, Stroke / 14.05.2014

MedicalResearch Interview with: Dr. Yan Qu Qingdao Municipal hospital Fruits and Vegetables Consumption and Risk of Stroke A Meta-Analysis of Prospective Cohort Studies MedicalResearch: What are the main findings of the study? Reply: First, both fruits and vegetables were found inversely associated with risk of stroke, and the relationships might be linear. Second, the inverse association of fruits and vegetables consumption with risk of stroke is consistent across subgroup analysis by outcome (stroke incidence and stroke mortality), location where the study was conducted (USA, Europe and Asia), sex (male and female), and stroke subtypes (ischemic and hemorrhagic). Third, citrus fruits, leafy vegetables and apples/pears were found inversely associated with risk of stroke. Fourth, very similar results were found in the subgroup analysis by status [yes: 0.78 (0.71-0.86) or no: 0.79 (0.74-0.85)] of adjusting for 6 or more of the 7 covariates (smoking, alcohol, blood pressure/hypertension, serum cholesterol, physical activity, body mass index, ≥3 dietary variables). These findings generally indicated that the association of fruits and vegetables consumption with the reduced risk of stroke may not be the result of confounding by the known factors. (more…)
Author Interviews, Nutrition, Weight Research / 08.05.2014

Mireille Serlie, MD PhD Academic Medical Center University of Amsterdam Department of Endocrinology and Metabolism Amsterdam, The NetherlandsMedicalResearch.com Interview with: Mireille Serlie, MD PhD Academic Medical Center University of Amsterdam Department of Endocrinology and Metabolism Amsterdam, The Netherlands MedicalResearch What are the main findings of the study? Dr. Serlie: We studied the effects of hypercaloric high sugar or high fat/high sugar drinks consumed with the 3 main meals (representing an increase in meal size) or in between the 3 main meals (representing an increase in meal frequency or snacking). All subjects gained a similar amount of body weight but only the ones that snacked showed an increase in liver and abdominal fat. This suggests that besides caloric content and diet composition, eating pattern independently contributes to liver and abdominal fat accumulation. We also observed a trend for a decrease in hepatic insulin sensitivity in the high fat/high sugar frequency group only. (more…)
Author Interviews, Nutrition, OBGYNE / 05.05.2014

Jessica A. Grieger (BSc(hons), R Nutr, PhD) Post-doctoral research fellow Robinson Research Institute, University of AdelaideMedicalResearch.com Interview with: Jessica A. Grieger (BSc(hons), R Nutr, PhD) Post-doctoral research fellow Robinson Research Institute, University of Adelaide   MedicalResearch:  What are the main findings of the study? Dr. Grieger: The study aimed to identify associations between maternal dietary patterns in the 12 months before conception on fetal growth and preterm delivery. We report that a one standard deviation increase in the scores on the high-protein/fruit pattern was associated with decreased likelihood for preterm birth, whereas a one standard deviation increase on the high-fat/sugar/takeaway pattern was associated with increased likelihood for preterm birth as well as shorter gestation and birth length. (more…)
Author Interviews, Coffee, Diabetes, Diabetologia / 04.05.2014

Dr. Frank B. Hu MD MPH PhD Professor of Nutrition and Epidemiology From the Departments of Nutrition and Epidemiology Harvard School of Public Health, Boston, MAMedicalResearch.com Interview with: Dr. Frank B. Hu MD MPH PhD Professor of Nutrition and Epidemiology From the Departments of Nutrition and Epidemiology Harvard School of Public Health, Boston, MA   MedicalResearch.com: What are the main findings of the study? Dr. Hu: We found that people who increased the amount of coffee they drank each day by more than one cup over a four-year period had a 11% lower risk for type 2 diabetes than those who made no changes to their coffee consumption, but those who decreased their coffee consumption by more than a cup per day increased their type 2 diabetes risk by 17%. (more…)
Author Interviews, Nature, Nutrition / 04.05.2014

Professor Gary Frost PhD RD Head of the Nutrition and Dietetic Research Group NIHR Senior Investigator Division of Diabetes, Endocrinology and Metabolism Faculty of Medicine Imperial College Hammersmith Campus London W12 ONNMedicalResearch.com Interview with: Professor Gary Frost PhD RD Head of the Nutrition and Dietetic Research Group NIHR Senior Investigator Division of Diabetes, Endocrinology and Metabolism Faculty of Medicine Imperial College Hammersmith Campus London W12 ONN MedicalResearch.com: What are the main findings of the study?  Prof. Frost: That acetate that is derived from the fermentation of dietary fiber in the colon by the microbiota is taken up by the hypothalamus in the brain.  In the hypothalamus the way the cells metabolize acetate creates a signal that suppresses appetite (more…)
Author Interviews, BMJ, Heart Disease, Nutrition / 02.05.2014

Shanshan Li, Doctoral candidate Department of Epidemiology Harvard School of Public Health, 655 Huntington Avenue Boston, MA 02115, USAMedicalResearch.com Interview with: Shanshan Li, Doctoral candidate Department of Epidemiology Harvard School of Public Health, 655 Huntington Avenue Boston, MA 02115, USA MedicalResearch.com: What are the main findings of the study? Answer: This is the first study to show that greater intake of dietary fiber, especially cereal fiber, was inversely associated with all-cause mortality. Participants increased their average dietary fiber intake after myocardial infarction (MI), and the greater the increase, the lower was the risk of subsequent all-cause and cardiovascular mortality. Overall, the benefits for increased fiber intake were strongest for fiber from cereal and grain sources. (more…)
Author Interviews, Nutrition / 18.04.2014

Dr. Annette Dickinson PhD Consultant to the Council for Responsible Nutrition.MedicalResearch.com Interview with: Dr. Annette Dickinson PhD Consultant to the Council for Responsible Nutrition.   MedicalResearch.com: What are the main findings of the study?   Dr. Dickinson: “A five-year series of consumer surveys (2007 to 2011) consistently found that about half of adult consumers use dietary supplements on a regular basis, and a higher percentage (about 2/3) report using dietary supplements when occasional as well as regular use is taken into account.  Over the five years, there was a shift in the pattern of supplement use, with the percentage of respondents who said they regularly used mostly a multivitamin declining, and the percentage who said they regularly used a variety of products increasing.  The top 7 products used were:  multivitamins, omega-3 fatty acids, calcium, vitamin D, vitamin C, B vitamins, and vitamin E.  The main reasons given for supplement use were for overall health and wellness (58% of users) and to fill nutrient gaps in the diet (42%).  Supplement users were more likely than nonusers to say they try to eat a balanced diet, visit their doctor regularly, get a good night's sleep, exercise regularly, and maintain a healthy weight.  This indicates that supplement use is part of an overall approach to seeking a healthy lifestyle.” (more…)
Author Interviews, Nutrition, Weight Research / 16.04.2014

MedicalResearch.com Interview with: Jeffrey R. Parker Assistant Professor of Marketing Robinson College of Business - Georgia State University MedicalResearch.com: What are the main findings of the study? Mr. Parker: Recently, there has been quite a bit of debate about the effectiveness of providing dish-specific calorie information (a practice called “calorie posting”) on restaurant menus in terms of the healthiness of consumers’ food choices. Some results suggest that such labels lead to lower-calorie choices, while other research shows that there is no effect. We examined one factor that might impact the effectiveness of calorie posting: the practice of grouping low-calorie options on a menu and labeling this category accordingly (i.e., incorporating a low-calorie menu/category in the menu)—which we call “calorie organizing”—as opposed to simply allowing them to appear in their natural categories with the caloric content appearing in the dish descriptions (e.g., Sandwiches, Salads, Pastas, etc.). On the surface it seems obvious that making low-calorie options easier to find—by giving them their own labeled category on the menu—would bolster the positive effects of calorie posting. However, we found the opposite: additionally calorie organizing an already calorie-posted menu regularly eliminates the benefits that calorie posting can have. We argued and found evidence indicating that the underlying cause of this effect stems from how consumers make decisions. Restaurant menus are often too large for a consumer to seriously consider all of the dishes. Some consumers typically eliminate large portions of the menu on the basis of simple criteria (e.g., “I don’t like seafood.”, “It’s too early to eat pasta.”, etc. ). Since consumers generally make negative inferences about low-calorie dishes (e.g., “They don’t taste good.”, “They are small dishes.”, etc.) they are likely to summarily dismiss all of the low-calorie options early in the decision process when the menu is calorie-organized (i.e., has grouped the low-calorie dished and labeled the new category accordingly). Thus, they are likely to choose as poorly as they would were they given no calorie information. In contrast, when the menu is just calorie-posted, and the low-calorie dishes appear in their natural categories, these dishes are unlikely to be dismissed in the early choice-simplification stages. Thus, low-calorie dishes are likely to be seriously considered in the final decision process, during which the pros and cons of dishes can be more comprehensively traded off, and are therefore more likely to be chosen. (more…)
Author Interviews, Blood Pressure - Hypertension, BMJ, Salt-Sodium / 15.04.2014

Dr. Feng He Wolfson Institute of Preventive Medicine Barts and The London School of Medicine and Dentistry Queen Mary University of London, London, UKMedicalResearch.com Interview with: Dr. Feng He Wolfson Institute of Preventive Medicine Barts and The London School of Medicine and Dentistry Queen Mary University of London, London, UK
MedicalResearch.com: What are the main findings of the study? Dr. He:
  • The UK salt reduction program has led to a fall in population blood pressure and thereby contributed to the reduction in stroke and heart disease deaths.
  •  In 2003, the UK Food Standards Agency and CASH (Consensus Action on Salt & Health) developed a salt reduction program. As approximately 80% of the salt in the diet is added to food by the food industry i.e. in processed foods, fast foods, canteen and restaurant foods etc, the public have no choice about eating it. Therefore progressive incremental targets to limit the amount of salt for each food category were set, which the industry had to achieve in a specified time. Reductions first started in 2003 and are continuing to this day.
  • The salt reduction program has been very successful and led to a 15% reduction in the average salt intake of the population, from 9.5g per day in 2003 to 8.1g per day in 2011 (P<0.05).
  • Over the same time period, blood pressure fell in the adult population by 3 mm Hg systolic and 1.4 mm Hg diastolic (P<0.0001). Stroke and heart disease deaths fell by 42% (P<0.0001) and 40% (P<0.0001) respectively.
  • It is possible that these falls in blood pressure and deaths from stroke and heart disease were attributable to various factors such as changes in diet, lifestyles and the improvement in the treatment of cardiovascular disease and its risk factors. Our further analysis showed that the reduction in salt intake played an important role, particularly in the falls in blood pressure.
  •  In a further analysis, we looked at individuals who were not on any drug treatment for blood pressure and a correction was made for all other variables that could have influenced blood pressure, apart from salt. There was still a fall in adult population blood pressure of 2.7mm Hg systolic/ 1.1mm Hg diastolic, (P <0.0001). This reduction in blood pressure could therefore be largely attributed to the fall in salt intake.
  •  It is well established that raised blood pressure throughout its range is a major cause of stroke and heart disease. The reduction in salt intake that led to a fall in blood pressure would have played an important role in both stroke and heart disease deaths.
  • Despite considerable progress being made on salt reduction, the average salt intake in England is still high. In 2011, it was 8.1 g/day which is over a third more salt than the recommended level of 6g/day. Therefore continuing and much greater efforts are needed to achieve further reductions in salt intake to prevent the maximum number of stroke and heart disease deaths. (more…)
Author Interviews, Breast Cancer, JNCI, Nutrition / 11.04.2014

dr_sabina-sieriMedicalResearch.com Interview with: Sabina Sieri, PhD Epidemiology and Prevention Unit Department of Preventive & Predictive Medicine Fondazione IRCCS Istituto Nazionale dei Tumori 20133 Milan – Italy MedicalResearch.com: What are the main findings of this study? Dr. Sieri: In our study we found that there was an increased risk of developing breast cancer from high saturated fat intake. High total and saturated fat intake were associated with greater risk of ER PR positive breast cancer. High saturated fat intake was also associated with a greater risk of HER2 negative disease. So, a high-fat diet increases breast cancer risk and, most conspicuously, a high saturated fat intake increases the risk of developing hormone-sensitive diseases, suggesting saturated fat involvement in the etiology of hormone-sensitive breast cancer. (more…)
Alzheimer's - Dementia, Author Interviews, Coffee / 08.04.2014

Prof. Dr. Christa E. Müller University of Bonn Pharmaceutical Institute Pharmaceutical Chemistry I An der Immenburg 4  D-53121 Bonn (Endenich) Germany  MedicalResearch.com Interview with: Prof. Dr. Christa E. Müller University of Bonn Pharmaceutical Institute Pharmaceutical Chemistry I An der Immenburg 4  D-53121 Bonn (Endenich) Germany MedicalResearch.com: What are the main findings of the study? Prof. Dr. Christa E. Müller: Genetically altered mice which show an aggregation of Tau protein and many symptoms of Alzheimer's Disease which progressively worsen with time was used. Caffeine was given to one group of mice at an early stage, when the symptoms were still moderate. The caffeine-treated mice showed better memory and less inflammation and brain damages in comparison to the non-treated control mice. This means that caffeine protected the mice to some extent. The side effects were moderate. (more…)
AHA Journals, Author Interviews, Blood Pressure - Hypertension, NIH, Nutrition, Salt-Sodium / 03.04.2014

MedicalResearch.com Interview with: Niels Graudal, MD, DrMSc Senior Consultant Department of Internal medicine/Infectious Medicine/Rheumatology IR4242 Copenhagen University Hospital, Rigshospitalet Denmark Dr. Graudal: There are no studies, which show what happens with the risk of cardiovascular death or mortality if you change your sodium intake. Our study shows the association of sodium intake as it is with cardiovascular disease and mortality, which is only the second best way to consider the problem, but as the best way does not exist we have accepted this approach. There have been two different assumptions concerning the risks of sodium intake. One is that there is an increasing risk of heart disease, stroke and death of salt intake above 2300 mg, and one is that salt is not dangerous at all. Our study shows that both positions partially may be true, as a salt intake above 4900 mg is associated with increased risk of cardiovascular disease and mortality, whereas the present normal salt intake of most of the world’s populations between 2300 mg and 4900 mg is not associated with any increased risks. In addition our study shows that a low sodium intake below 2300 mg is also associated with increased risk of cardiovascular disease and death. (more…)
Author Interviews, Coffee, Gastrointestinal Disease, Hepatitis - Liver Disease / 03.04.2014

Woon-Puay Koh (Associate Professor) Office of Clinical Sciences Duke-NUS Graduate Medical School Singapore 8 College Road Level 4 | Singapore 169857MedicalResearch.com Interview with: Woon-Puay Koh (Associate Professor) Office of Clinical Sciences Duke-NUS Graduate Medical School Singapore 8 College Road Level 4 | Singapore 169857   MedicalResearch.com:  What are the main findings of the study? Answer: The main finding is that coffee intake was associated with a lower risk of death from cirrhosis, specifically for non-viral hepatitis related cirrhosis. Subjects who drank two or more cups per day had a 66% reduction in mortality risk, compared to non-daily coffee drinkers. However, coffee intake was not associated with viral hepatitis B related cirrhosis mortality. (more…)
Mediterranean Diet, NIH, Nutrition, Weight Research / 02.04.2014

Dr. Milan K Piya NIHR Clinical Lecturer in Diabetes and Endocrinology Warwick Medical School, University of Warwick; University Hospitals Coventry and Warwickshire NHS Trust Coventry, UKMedicalResearch.com Interview with: Dr. Milan K Piya NIHR Clinical Lecturer in Diabetes and Endocrinology Warwick Medical School, University of Warwick; University Hospitals Coventry and Warwickshire NHS Trust Coventry, UK MedicalResearch.com: What are the main findings of the study? Answer: Our studies have identified two main findings: Firstly that the size or frequency of the meal doesn’t affect the calories we burn in a day, but what matters most for losing weight is counting calories. Secondly, by carrying more weight, more endotoxin enters the circulation to cause inflammation and eating more often will exacerbate this risk which has been linked to metabolic diseases such as type-2 diabetes. (more…)
Author Interviews, BMJ, Nutrition / 02.04.2014

Dr Oyinlola Oyebode Specialist Registrar in Public Health Dept of Epidemiology & Public Health University College London London WC1E 6BTMedicalResearch.com Interview with: Dr Oyinlola Oyebode Specialist Registrar in Public Health Dept of Epidemiology & Public Health University College London MedicalResearch.com: What are the main findings of the study? Dr. Oyebode: We found that the more fruit and vegetables consumed, the lower the risk of death from any cause, from cancer or from heart disease or stroke. We found that vegetables were better than fruit at equivalent amounts. (more…)
Author Interviews, BMJ, Gastrointestinal Disease, Pediatrics, Probiotics / 02.04.2014

Dr Valerie Sung MBBS(Hons) FRACP MPH NHMRC PhD Candidate, Department of Paediatrics, University of Melbourne, and Community Health Services Research, Murdoch Childrens Research Institute Paediatrician, Centre for Community Child Health, The Royal Children’s HospitalMedicalResearch.com Invitation with: Dr Valerie Sung MBBS(Hons) FRACP MPH NHMRC PhD Candidate, Department of Paediatrics, University of Melbourne, and Community Health Services Research, Murdoch Childrens Research Institute Paediatrician, Centre for Community Child Health The Royal Children’s Hospital MedicalResearch.com: What are the main findings of the study? Dr. Sung: Lactobacillus reuteri was NOT effective in reducing crying or fussing in infants with colic, whether they are breast or formula fed. This is the largest and most rigorous trial to date to show this. (more…)
Author Interviews, Nutrition, Sugar / 28.03.2014

MedicalResearch.com Interview with: JeffJeff Niederdeppe Assistant Professor Department of Communication Cornell University. Niederdeppe Assistant Professor Department of Communication Cornell University.   MedicalResearch.com: What are the main findings of the study? Answer: We conducted an Internet-based survey (N = 1319) with a nationally-representative sample of U.S. adults aged 18–64 during the fall of 2012. Americans voiced the highest levels of support for calorie labeling (65%) and removing drinks from schools (62%), and the lowest support for taxes (22%) or portion size restrictions (26%). Americans were evenly split on whether or not they support restricting sugary drink to children (50%) and requiring TV stations to air ads promoting healthy eating and exercise equal to the time used to advertise for sugary drinks (51%). Democrats and those with negative views of soda companies are more likely to support each of these policies. (more…)
Author Interviews, Nutrition, Weight Research / 28.03.2014

Barbara J. Rolls, PhD Department of Nutritional Sciences The Pennsylvania State University, 226 Henderson Building University Park, PA 16802-6501MedicalResearch.com Interview with: Barbara J. Rolls, PhD Department of Nutritional Sciences The Pennsylvania State University, 226 Henderson Building University Park, PA 16802-6501 MedicalResearch.com: What are the main findings of the study? Dr. Rolls:  We found that as we reduced the flake size of a breakfast cereal so that it filled a smaller volume, individuals ate a greater weight and more calories of the cereal. On four occasions, we served a popular wheat flake cereal, or the same weight of cereal crushed to 80%, 60%, or 40% of its volume, to 41 adults for breakfast. As the flake size was reduced, people made reductions in the volume of cereal they poured, but they still took a greater amount of weight and calories. They ended up eating 72 more calories at breakfast when they ate the cereal with the smallest flake size, an increase of 34%. These findings show that variations in food volume due to the size of individual food pieces affect the portion of food that people take, which in turn affects how much they eat. (more…)
Author Interviews, NIH, Nutrition, Sugar / 27.03.2014

Laureen Smith, PhD Associate Professor College of Nursing, The Ohio State University Columbus, OH 43210MedicalResearch.com Interview with: Laureen Smith, PhD Associate Professor College of Nursing, The Ohio State University Columbus, OH 43210 MedicalResearch.com: What are the main findings of the study? Dr. Smith: Daily sugar-sweetened beverage decreased significantly by about 1 serving per day. Also weekly consumption decreased from an average of over 4 days per week to about 2 ½ days per week. Generally, the teens were drinking the beverages fewer days per week and less servings on the days they did consume them. These changes were maintained on their own for a month after the intervention ended. Water consumption increased nearly 20 percent immediately post intervention and continued to increase at 30 days post-intervention. (more…)
Author Interviews, Inflammation, Nutrition, Vitamin K / 25.03.2014

MedicalResearch.com Interview with Mònica Bulló PhD Human Nutrition Unit Department of Biochemistry & Biotechnology IISPV  School of Medicine Rovira i Virgili University Sant Llorenç, Spain MedicalResearch.com: What are the main findings of the study? Dr Bulló: There is some evidence that different dietary forms of vitamin K could exert varying effects on health, however no study to date has simultaneously evaluated the potential effects of the main vitamin K forms on cancer and cardiovascular mortality. We conducted a prospective, epidemiologic study involving 7,216 elderly subjects at high cardiovascular risk who were followed for about 5 years.The results of the present study show, for the first time that an increase in dietary intake of both forms of vitamin K is related to a lower risk of cardiovascular mortality, cancer mortality or all-cause mortality. (more…)
Author Interviews, Heart Disease, JAMA, NIH, Omega-3 Fatty Acids / 19.03.2014

MedicalResearch.com Interview with: Denise Bonds, MD, MPH National Heart, Lung, and Blood Institute (NHLBI)  MedicalResearch.com: What are the main findings of the study? Dr.Bonds: We found no cardiovascular benefit to supplementation of the diet with either omega-3 fatty acids or with the macular xanthophyll’s lutein and zeaxanthin. (more…)
Author Interviews, BMJ, Brigham & Women's - Harvard, Genetic Research, Medical Research Centers, Nutrition, Weight Research / 19.03.2014

Prof. Lu Qi, Assistant Professor, Department of Nutrition Harvard School of Public Health and Channing Division of Network Medicine Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MAMedicalResearch.com Interview with: Prof. Lu Qi, Assistant Professor, Department of Nutrition Harvard School of Public Health and Channing Division of Network Medicine Department of Medicine, Brigham and Women’s Hospital and Harvard Medical School, Boston, MA MedicalResearch.com: What are the main findings of the study? Dr. Lu Qi: In this study, we for the first time provide reproducible evidence from three large cohort studies to show that the association between regular consumption of fried foods and higher BMI was particularly pronounced among people with a greater genetic predisposition to obesity. On the other hand, the adverse genetic effects on BMI were also amplified by consuming more fried foods, the effects among those who ate fried foods more than four times a week was about twice as large compared with those who ate them less than once a week. (more…)
Author Interviews, Nutrition, Pediatrics, Vanderbilt, Weight Research / 19.03.2014

Dr. Eliana M. Perrin, MD, MPH Associate Vice Chancellor for Research, and Director, Office of Research Development University of North Carolina at Chapel Hill  and Associate Professor Department of Pediatrics, Division of General Pediatrics and Adolescent Medicine University of North Carolina at Chapel Hill, School of Medicine Chapel Hill, NC 27599-7225MedicalResearch.com Interview Invitation with: Dr. Eliana M. Perrin, MD, MPH Associate Vice Chancellor for Research, and Director, Office of Research Development University of North Carolina at Chapel Hill  and Associate Professor Department of Pediatrics, Division of General Pediatrics and Adolescent Medicine University of North Carolina at Chapel Hill, School of Medicine Chapel Hill, NC 27599-7225 MedicalResearch.com: What are the main findings of the study? Dr. Perrin: The study included a large, diverse sample of 863 low-income parents of two-month-olds participating in Greenlight, an obesity prevention trial taking place at four medical centers: UNC, New York University, Vanderbilt University and the University of Miami.  Among all of the parents, behaviors that are thought to be related to later obesity were highly prevalent. Exclusive formula feeding was more than twice as common (45 percent) as exclusive breastfeeding (19 percent). Twelve percent had already introduced solid food, 43 percent put infants to bed with bottles, 23 percent propped bottles instead of holding the bottle by hand (which can result in overfeeding), 20 percent always fed when the infant cried, and 38 percent always tried to get their children to finish their milk.  In addition, 90 percent of the infants were exposed to television and 50 percent actively watched TV (meaning parents put their children in front of the television in order to watch).  There were differences in these behaviors by race and ethnicity, and study results show that culturally-tailored counseling should be offered to parents of different backgrounds who may feed and play with their children differently. (more…)
Annals Internal Medicine, Author Interviews, Heart Disease, Lipids, Nutrition / 17.03.2014

Rajiv Chowdhury MD, PhD Cardiovascular Epidemiologist Department of Public Health and Primary Care University of CambridgeMedicalResearch.com Interview with: Rajiv Chowdhury MD, PhD Cardiovascular Epidemiologist Department of Public Health and Primary Care University of Cambridge MedicalResearch.com: What are the main findings of the study? Dr. Chowdhury: Total saturated fatty acid, whether measured as a dietary intake variable or in the bloodstream as a biomarker, was not associated with coronary disease risk in combining all available prospective observational studies. Similarly, there were non-significant overall associations in the prospective studies that involved assessments of total monounsaturated fatty acids, long-chain omega-3 and omega-6 polyunsaturated fatty acids. However, we found diversity in the observational associations between specific circulating long-chain omega-3 and omega-6 fatty acids with coronary risk, with some evidence that circulating levels of eicosapentaenoic and docosahexaenoic acids (ie, the two main types of long-chain omega-3 polyunsaturated fatty acids), and arachidonic acid are each associated with lower coronary risk. Similarly, within saturated fatty acids, there were positive, however, non-significant associations observed for circulating blood composition of palmitic and stearic acids (found largely in palm oil and animal fats, respectively), whereas circulating margaric acid (a milk fat) had a significant inverse association. Additionally, when we investigated the randomised controlled trials that reported on the effects of omega-3 and omega-6 fatty acids on reducing coronary outcomes, there was no significant overall association observed. (more…)
Author Interviews, Blood Pressure - Hypertension, Nutrition, Weight Research / 06.03.2014

Beverly B. Green, MD, MPH GroupHealth Research Institute Seattle WAMedicalResearch.com Interview with: Beverly B. Green, MD, MPH GroupHealth Research Institute Seattle WA   MedicalResearch.com: What are the main findings of the study? Dr. Green: We found that Group Health patients who were overweight and had hypertension were more likely to have lost 10 pounds in six months if they had secure online access to a dietitian than if they received only information and usual care. The patients really loved this intervention—and having access to a dietitian to work with them toward a healthier lifestyle. Although blood pressure and heart risk trended lower in the intervention group, the differences weren’t significant—unlike their weight. (more…)