Author Interviews, Depression, Heart Disease, JAMA / 28.09.2015
Cognitive Behavior Therapy Improves Depression in Heart Failure Patients
MedicalResearch.com Interview with:
Kenneth E. Freedland, PhD
Professor of Psychiatry and Psychology
Washington University School of Medicine
St. Louis, Missouri
Medical Research: What is the background for this study? What are the main findings?
Dr. Freedland: Major depression is a common problem in patients with heart failure, and it makes heart failure self-care tasks such as daily weight checks and compliance with dietary restrictions more difficult for these them. Unfortunately, recent clinical trials have shown that both depression and inadequate self-care can be hard to treat in patients with heart failure.
Cognitive behavior therapy (CBT) is often used to treat depression in otherwise healthy individuals, but it hasn’t been tested in patients with heart failure. We added a self-care component to the standard CBT treatment protocol and conducted a clinical trial to determine whether it is effective both for depression and for self-care. We randomized 158 heart failure patients to cognitive behavior therapy or to usual care, and both groups received heart failure education. About 1/3 of the patients in both groups were also taking antidepressant medications. The intervention was effective for depression, with remission rates of 51% in the cognitive behavior therapy group compared to only 20% in the usual care group. However, it was not effective for heart failure self-care.
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