Prof. Monsonego Ornan[/caption]
Efrat Monsonego Ornan, Ph.D
Head of School of Nutritional Sciences
Institute of Biochemistry and Nutrition
The Robert H. Smith Faculty of Agriculture,
Food and Environment
The Hebrew University of Jerusalem
MedicalResearch.com: What is the background for this study?
Response: Food supplies in recent decades have been dominated by heavily processed, ready-to-eat products. Essentially, 75% of all world food sales are of processed foods. Over the past 30 years, children’s ultra-processed food intake has increased markedly, with 50% of the children in the US consuming these foods. Only in the US does UPF comprise 58% of energy intake, of which 90% is derived from added sugars. This reflects children’s excessive consumption of food and drink that are high in fat and refined sugars but do not provide appropriate levels of the proteins, vitamins and minerals required for growth.
The negative health outcomes of excessive consumption of Ultra-processed food are well known, include obesity, metabolic syndrome and diabetes, and considered as the current world epidemic; the fact that children, during their postnatal development period (birth to adolescent), are the target of the Ultra-processed food industry is very disturbing in terms of public health. Bone development and growth are the characteristic phenomena of the childhood period. Yet, in spite of the huge importance of nutrition to bone development, the impact of Ultra-processed food consumption on skeleton development during childhood has never been studied directly, and this was the purpose of our study.
To this end, we used young rats which are an excellent pre-clinical model for growth and fed them with either the recommended diet for their age or a diet comprised of a typical Ultra-processed meal (a roll, hamburger, tomatoes, lettuce, ketchup and French fries) and a caloric soft drink.
Dr. Raisi-Estabra[/caption]
Dr Zahra Raisi-Estabragh, PhD fellow
Cardiologist Trainee at Queen Mary University of London and
Barts Health NHS Trust
MedicalResearch.com: What is the background for this study?
Response: Previous studies have linked greater consumption of red and processed meat to poorer clinical cardiovascular outcomes, for example, higher risk of having a heart attack or of dying from heart disease. However, the biological mechanisms underlying these relationships are not well understood. Furthermore, the impact of meat intake on more direct measures of heart health, such as, structure and function of the heart and blood vessels, has not been previously studied in large cohorts. Examining how meat intake may influence different aspects of cardiovascular health can help us better understand its health effects.
Dr. Plym[/caption]
Dr. Anna Plym PhD
Postdoctoral Research Fellow
Brigham and Women's Hospital
Harvard T.H. Chan School of Public Health
MedicalResearch.com: What is the background for this study? What are the main elements of the healthy lifestyle?
Response: Prostate cancer is the most heritable of all cancers, with genetic factors accounting for a large proportion of cases. Although we do not currently know about all the genetic factors contributing, a recent study identified 269 genetic markers for prostate cancer, validated in multiple independent populations (Conti et al., Nature Genetics 2021, Plym et al, JNCI, 2021: https://academic.oup.com/jnci/advance-article-abstract/doi/10.1093/jnci/djab058/6207974). Based on a polygenic risk score derived from these 269 markers, we observed that men with a high polygenic risk score have over a 50% risk of developing prostate cancer within their lifetime. With this excess risk in mind, we were interested in possible ways in which the genetic risk of prostate could be attenuated. An increasing number of studies have suggested that lifestyle factors can affect the risk of lethal prostate cancer – however, these studies have seldom incorporated genetic factors. We know from other diseases that a healthy lifestyle is of benefit for individuals at high genetic risk, and we hypothesized that this would be the case for prostate cancer as well. In this study, we examined a healthy lifestyle score for lethal prostate cancer consisting of six components: healthy weight (BMI < 30), not smoking (never smoked or quit > 10 years ago), vigorous physical exercise (3 or more hours per week), high intake of tomatoes or tomato-based products (7 servings or more per week), high intake of fatty fish (1 or more serving per week) and low intake of processed meat (less than 3 servings/week of beef or pork hot dogs, bacon, salami, bologna, or other processed meat sandwiches) (Kenfield et al, JCO, 2016).
The first step that you should take to finding inner peace is to practice yoga and meditation regularly. Yoga and meditation can give you the chance to slow down and reflect, as well as to clear your mind of the worries and negative thoughts that are concerning you. Not only this, but deep breathing is also an important aspect of both yoga and meditation as this can help you to ground yourself and to reconnect with the world around you.
Nadia Koyratty[/caption]
Nadia Koyratty PhD student
Department of Epidemiology and Environmental Health
University at Buffalo
State University of New York
MedicalResearch.com: What is the background for this study?
Response: The literature suggests that sugars contribute to the incidence of breast cancer, but few exists on the prognosis after a breast cancer diagnosis.
MedicalResearch.com: What are the main findings?
Response: Compared to breast cancer patients who never or rarely drank non-diet soda, those who reported drinking non-diet soda five times or more per week had a 62% higher likelihood of dying from any causes, and were 85% more likely to die from breast cancer specifically.
Anne Yuk-Lam Ho, MPH
Million Veteran Program (MVP) Data Core
MVP Coordinating Center
VA Boston Healthcare System
MedicalResearch.com: What is the background for this study?
Response: Cardiovascular disease (CVD) has been the leading cause of morbidity and mortality globally. Prevalence of CVD among US population is approximately 7% which places huge burden on our healthcare systems. And prevalence of CVD is as high as 28% among veterans at the VA healthcare system as veteran users are primarily older male with more histories of comorbidities. Most CVD risk factors including lipids and blood pressure can be controlled by lifestyle modifications, such as diet.
Chocolate is among dietary factors that play a role in modulating CVD risk factors is widely consumed in the US (~2.8 billion pounds annually. Although previous studies have reported beneficial effects of chocolate and/or cacao products (rich in flavonoids) on lipids, glucose metabolism and risk of diabetes, and lipids, little is known about the association of chocolate intake with coronary artery disease (CAD) among US veterans. Thus, sought to test the hypothesis that chocolate consumption is associated with a lower risk of CAD among xxx US veterans enrolled in the Million Veteran Program.
Dr. Crosbie[/caption]
Eric Crosbie, PhD, MA
Assistant Professor
School of Community Health Sciences
Ozmen Institute for Global Studies
University of Nevada Reno
MedicalResearch.com: What is the background for this study?
Response: My colleague Dr. Laura Schmidt and I established a framework for studying preemption (when a higher level of government limits the authority of lower levels to enact laws) by studying the history of state preemption of local tobacco control policies in the U.S., which we published last year (2020) in AJPH. We noticed the same strategies that the tobacco industry employed were now being used by the beverage industry to suppress local taxation policies on sugar sweetened beverages (e.g. soda, coffee drinks, energy drinks, etc). We used this preemption framework to publish a new study this year in AJPH that analyzed state preemption of local sugar sweetened beverage taxes in the U.S.
Dr. Chaiyakunapruk[/caption]
Nathorn (Nui) Chaiyakunapruk PharmD, PhD
Professor, Department of Pharmacotherapy
University of Utah College of Pharmacy
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Colorectal cancer is one of the cancers for which we found that the risk can be significantly reduced by modifying diet. Individual components of your diet can contribute to an overall healthy diet pattern to lower the risk of colorectal cancer or increase it. Strong scientific evidence shows that limiting red meat and alcohol consumption, eating foods containing fiber and calcium, consumption of dairy products especially yogurt can help prevent colorectal cancer.
Reduction of brain plaques and tangles leads to improved memory, focus, concentration and executive function as has been shown by over 30 years of scientific studies in major medical journals....
Do you know how many calories are in your nightly glass of wine or in that can of soda you had for lunch? You probably don’t, but you should know, and you should make it a priority to know exactly what is in your drinks....
The US dietary guidelines may recommend replacing whole eggs with egg whites/substitutes or alternative protein sources for facilitating cardiovascular health and long-term survival....
Dr. Willette[/caption]
Auriel Willette, PhD
Assistant Professor
Food Science and Human Nutrition
Iowa State University
MedicalResearch.com: What is the background for this study?
Response: To date, pharmacology therapies done to slow down or halt Alzheimer's disease have been inconclusive. Lifestyle interventions like changes in diet and activity are also mixed but do show some promise. Dietary clinical trials or self-reported diet have tended to focus on groups of foods such as the Mediterranean or MIND diet. To build from this excellent work, we were curious if we could pinpoint specific foods that were correlated with changes in fluid intelligence over time. Fluid intelligence represents our ability to creatively use existing knowledge, working memory, and other components of "thinking flexibly."
Further, we tested if these patterns of association differed based on genetic risk. In this case, genetic risk was defined as having a family history of Alzheimer's disease or having 1-2 "bad" copies of the Apolipoprotein E (APOE) gene, which is the strongest genetic risk factor for Alzheimer's disease.
Dr. Nagata[/caption]
Jason M Nagata M.D., M.Sc
Assistant Professor of Pediatrics
Division of Adolescent and Young Adult Medicine
Department of Pediatrics, University of California
San Francisco, San Francisco, CA
MedicalResearch.com: What is the background for this study?
Response: During the COVID-19 pandemic, food insecurity is expected to rise given economic uncertainty and job losses. Vulnerable and marginalized populations are disproportionately affected by both COVID-19 and food insecurity.
Dr. Bayes-Genis[/caption]
Antoni Bayes-Genis, MD, PhD, FESC, FHFA
Head, Heart Institute. Hospital Universitari Germans Trias i Pujol
Full Professor, Autonomous University Barcelona
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: Omega-3 fatty acids are incorporated into the phospholipids of cellular membranes, including cardiac contractile cells, and have a wide range of demonstrated physiological effects. Several potential mechanisms have been investigated, including antiarrhythmic, anti-inflammatory, and endothelial.
Omega-3 fatty acids lower heart rate and improve heart rate variability, both associated with lower sudden cardiac death risk, one of the complications that may occur after a myocardial infarction.
Increased omega-3 fatty acids also enhance arterial elasticity by increasing endothelium-derived vasodilators, which is associated with blood pressure–lowering effects.
They also have a cardioprotective effect on platelet-monocyte aggregation, and lower triglyceride levels.
Dr. Bragg[/caption]
Marie Bragg, PhD
Assistant Professor, Department of Population Health on Health Choice
NYU College of Global Public Health
MedicalResearch.com: What is the background for this study?
Response: We know from previous research that children who see food advertisements eat significantly more calories than children who see non-food advertisements. Those studies led the World Health Organization and National Academy of Medicine to issue reports declaring that exposure to food advertising is a major driver of childhood obesity.
What we don’t know is how frequently unhealthy food and beverage brands are appearing in YouTube videos posted by Kid Influencers. Kid influences are children whose parents film videos of the child playing with toys, unwrapping presents, eating food, or engaging in other family-friendly activities. The parents then post the videos to YouTube for other children and parents to view for entertainment.
Dr. Mora[/caption]
Samia Mora, MD MHS
Associate Professor, Harvard Medical School
Director, Center for Lipid Metabolomics
Brigham and Women’s Hospital
Boston, MA 02215
@SamiaMoraMD
MedicalResearch.com: What is the background for this study?
Response: Couples, both married couples and domestic partners, are likely to share similar environmental exposures, adopt similar behavior patterns, and have similar characteristics. However, the degree to which couples share similar levels of cardiovascular (CV) risk factors and behaviors is uncertain. If high levels of poor CV risk factor measures and behaviors are common in both members of a couple, programs that target improvement of these risk factors and behaviors may simultaneously benefit CV health in both members of the couple.
Dr. Nagata, MD[/caption]
Jason Nagata, MD, MSc
Assistant Professor of Pediatrics
University of California, San Francisco
San Francisco, California, USA
MedicalResearch.com: What is the background for this study?
Response: During the COVID-19 pandemic, food insecurity is expected to rise given economic uncertainty and job losses. Vulnerable and marginalized populations are disproportionately affected by both COVID-19 and food insecurity.
MedicalResearch.com: What are the main findings?
Response: In this perspective, we argue that food insecurity and COVID-19 can exacerbate one another via bidirectional links. Experiencing food insecurity can lead to nutritional deficiencies and weakened host defenses, increasing susceptibility to COVID-19 infection. Food insecurity is also associated with chronic medical conditions which may lead to a higher risk of severe COVID-19 illness.
Conversely, people with COVID-19 may not be able to work, generate income, or procure food while quarantined, which may worsen food insecurity.
Prof. James[/caption]
Professor Jack E. James, PhD
Reykjavík University
Reykjavík Iceland
MedicalResearch.com: What prompted this study?
Response: Chronic exposure to any chemical during pregnancy is cause for concern. There should be no exception simply because that chemical, caffeine, happens to be widely consumed. Caffeine is a habit-forming substance of no nutritional value. If anything, its widespread consumption suggests that it should be given special attention. Concern is heightened by what is known about the effects of caffeine on the human body, where it affects neural processes in the brain, including networks that control respiration and heart function.
When consumed during pregnancy, caffeine readily crosses the placenta, exposing the fetus to the drug. Notably, the fetus is largely physically incapable of metabolising caffeine – that ability develops during the first year of life. Pregnancy studies have shown that caffeine can interfere with fetal heart function and oxygenation.
The Committee's scientific report shines a light on the growing body of evidence that shows choline plays a critical role in health during specific life stages and is under consumed among all Americans at every life stage....
Dr. Brantley[/caption]
Erin Brantley, PhD, MPH
Senior Research Associate
Department of Health Policy and Management
Milken Institute School of Public Health
Preferred pronouns: she/her/hers
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: We looked at what happened when work requirements for the Supplemental Nutrition Assistance Program Participation, or SNAP, were turned on in many places after the Great Recession.
We found large drops in participation in SNAP benefits due to work requirements, and that black recipients were more likely to lose benefits than white recipients. We think this is driven by the fact that black workers face higher unemployment rates than white workers, and work requirement policies do not take this into account.
We also found that some people who report having disabilities lost benefits, even though the intent of work requirements is that they apply to people without disabilities.
Dr. Valdes[/caption]
Ana M Valdes MA PhD
Associate Professor and Reader in Musculoskeletal Genetics
Professor in Molecular and Genetic Epidemiology from 1 August 2020
Deputy Head of Division, Rheumatology Orthopaedics and Dermatology
NIHR Nottingham Biomedical Research Centre - Research Area Lead
School of Medicine
University of Nottingham
MedicalResearch.com: What is the background for this study?
Response: Given the relevance of blood sugar and blood lipid levels, we wanted to be able to quantify how much meal content, time of day, sleep, gut microbiome, other individual characteristics contribute to glucose and to develop models to describe how the interactions between individual characteristics, meal composition, other sources of variation on postprandial glycemia.
We also wished to compare glucose data to other postrpandial metabolic responses, specifically c-peptide and triglyceride levels.
It is important to remember that the FDA does not regulate dietary supplements. This means that, unlike medications and drugs, supplements do not have to meet any strict standards....
Dr. Pesch[/caption]
Megan H. Pesch, MD, MS, FAAP
Assistant Professor
C.S. Mott Children’s Hospital
University of Michigan
MedicalResearch.com: What is the background for this study?
Response: Picky eating is common among children and is often both concerning to parents. Healthcare providers may reassure parents that their child will “outgrow” picky eating, however there have been few longitudinal studies examining the trajectories of picky eating in children, as well as associated trends in their growth.
In our study we examined the trajectories of picky eating in US children over a 5 year period. We also examined how these picky eating trends were associated with child characteristics, weight status and mother’s feeding behaviors.