Author Interviews, COVID -19 Coronavirus, Pediatrics, Weight Research / 09.09.2025
Nemours Study Finds COVID Influenced Weight Gain Trajectories in Children
MedicalResearch.com Interview with:
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Dr. Thao Ly Phan[/caption]
Thao-Ly Phan, MD, MPH
Medical Director, Nemours Children's Health
Professor of Pediatrics
Thomas Jefferson University
MedicalResearch.com: What is the background for this study?
Response: The impacts of the COVID-19 pandemic have been extensively studied in adults, but there has been limited exploration of its effects on children and adolescents. While several studies have described weight gain trends in children during the pandemic, less is known about how having a diagnosis of COVID-19 contributed to these trends. Our study drew on the NIH’s National Clinical Cohort Collaborative database, a real-world database of electronic health data from over 90 institutions across the country. We used this dataset’s unique features to compare a diverse group of more than 11,000 children diagnosed with COVID-19 to a matched cohort of children without a diagnosis of COVID-19.
Dr. Thao Ly Phan[/caption]
Thao-Ly Phan, MD, MPH
Medical Director, Nemours Children's Health
Professor of Pediatrics
Thomas Jefferson University
MedicalResearch.com: What is the background for this study?
Response: The impacts of the COVID-19 pandemic have been extensively studied in adults, but there has been limited exploration of its effects on children and adolescents. While several studies have described weight gain trends in children during the pandemic, less is known about how having a diagnosis of COVID-19 contributed to these trends. Our study drew on the NIH’s National Clinical Cohort Collaborative database, a real-world database of electronic health data from over 90 institutions across the country. We used this dataset’s unique features to compare a diverse group of more than 11,000 children diagnosed with COVID-19 to a matched cohort of children without a diagnosis of COVID-19.
Dr. Hazen[/caption]
Stanley Hazen, MD, PhD
Chair, Cardiovascular & Metabolic Sciences
Lerner Research Institute
CoSection head, Preventive Cardiology & Cardiovascular Rehabilitation
Heart, Vascular and Thoracic Institute
Cleveland Clinic
MedicalResearch.com: What is the background for this study?
Response: One of the unique features of COVID is that in some subjects, there unfortunately appear to be long term adverse effects that can occur following resolution of the acute infection. These studies add to the growing body of data showing that COVID-19 infection can enhance risk for experiencing adverse cardiac events (heart attack, stroke, and death) over time.
Prof. Takeshi[/caption]
Prof. Takeshi Asai
Faculty of Health and Sports Sciences, University of Tsukuba,
Tsukuba Japan
Faculty of Physical Education, International Pacific University
Okayama, Japan
MedicalResearch.com: What is the background for this study?
Response: In the early stages of the COVID-19 pandemic, contact and droplet transmission were considered the main routes of infection. However, it was later demonstrated that airborne transmission is an important route. Therefore, accumulating real-world data on airborne transmission was deemed crucial.
Dr. Sood[/caption]
Neeraj Sood, PhD
Verna and Peter Dauterive Hall
University Park Campus
University of Southern California
Los Angeles, CA
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: We conducted this study to inform school COVID-19 policies.
The main findings are that the median duration of infectivity after a positive COVID-19 test in children is 3 days. The median duration of infectivity does not vary with vaccination.
MedicalResearch.com: What is the background for this study?
Response: I became interested in dog's sense of smell several years ago while doing therapy dog demonstrations at the California Science Center in Los Angeles during a special traveling exhibit "Dogs! A Science Tail." (Now at the Orlando Science Center). I did a lot of research on this topic and taught children about it through the Los Angeles Public Library using my Great Pyrenees therapy dogs. Then, COVID broke out and I expanded my research into any work being done to possibly utilize scent dogs for screening and testing for COVID. I found only a few such studies. However, I fortuitously met Heather Junqueira of BioScent, Inc. (in Florida) online and she was beginning to successfully teach her beagles to detect COVID-related odors. She agreed to co-author a peer-reviewed review paper with me. That led to our first paper -
Dickey, T, Junqueira, H. Toward the use of medical scent dogs for COVID-19 screening. J Osteopath Med 2021;1(2): 141-148.
Dr. Wall[/caption]
Dr Emma Wall
Senior Clinical Research Fellow, UCLH-Crick Legacy study
Consultant Infectious Diseases UCLH
MedicalResearch.com: What is the background for this study?
Response: Since April 2022, both the UK and US have changed their COVID-19 isolation and testing policies. The impact these changes in the guidance and vaccination on community-acquired COVID-19 caused by recent SARS-CoV-2 variants of concern (VOC) has not been fully tested, including infections with BA.2. We aimed to characterise both symptoms and viral loads over the course of COVID-19 infection in otherwise-healthy, vaccinated, non-hospitalised adults, to assess whether current guidance remains justified. All participants were included in the UCLH-Crick Legacy study, a prospective, observational cohort study of otherwise healthy adults who have been taking part in regular workplace testing for SARS-CoV-2 in London
We sent swabs by same-day courier every other day to all adults who reported a positive PCR or lateral flow test to the study team up to day 10 after the start of each infection. We confirmed which variant caused the infection by PCR and sequencing. All participants completed linked symptom diaries.
We compared symptoms and changes in the amount of virus detected in the nose and throat during infection between study participants reporting COVID-19 caused by VOCs Delta and Omicron BA.1 and BA.2. We then analysed how many of our participants would meet current UK/US isolation guidelines.
Dr. Georgiou[/caption]
Archelle Georgiou, MD
Chief Health Officer for Starkey
Starkey Hearing Technologies
Eden Prairie, Minnesota
MedicalResearch.com: What is the background for this study?
Response: In August 2021, Starkey introduced a vaccination incentive program for employees in the U.S. to provide education on COVID-19 and encourage vaccinations. The program encouraged employees to watch and acknowledge online educational information and report their vaccination status. Those fully vaccinated and who submitted proof of vaccination by September 2021, including employees who were vaccinated prior to the incentive announcement, received $1,000.
Dr. Rathmann[/caption]
Prof. Wolfgang Rathmann MSPH
Prof. of Epidemiology
Deputy Director, Institute for Biometrics and Epidemiology,
German Diabetes Center, Heinrich Heine University
Düsseldorf, Germany
MedicalResearch.com: What is the background for this study?
Response: Diabetes is associated with a poor prognosis of COVID-19. There have been raised concerns about a bidirectional relationship between diabetes and COVID-19. Recent studies raised the possibility that SARS-CoV-2 can cause diabetes. However, there is a lack of studies investigating the incidence of diabetes after recovery from COVID-19 in mild cases.
To provide more evidence, we analyzed electronic health records from 1,171 general and internal medicine practices across Germany between March 2020 and January 2021. This included 35,865 patients who were diagnosed with COVID-19. The incidence of diabetes after COVID-19 was compared with patients, who were diagnosed with an acute upper respiratory tract infection (AURI), matched for sex, age, and comorbidities including obesity, high blood pressure, high cholesterol, heart attack, and stroke.
Dr. Kao-Ping Chua[/caption]
Kao-Ping Chua, MD, PhD
Assistant Professor,
Department of Pediatrics
Assistant Professor,
Health Management and Policy
School of Public Health
University of Michigan
MedicalResearch.com: What is the background for this study?
Response: In 2020, most insurers waived the cost of COVID-19 hospitalization for patients. In early 2021, many major insurers started to abandon those waivers. By August 2021, the vast majority of insurers had started billing patients for COVID-19 hospitalizations again.