Author Interviews, Cancer Research, Exercise - Fitness / 10.10.2018

MedicalResearch.com Interview with: Laurien Buffart, PhD Chair Amsterdam eXercise in Oncology (AXiON) research Departments of Epidemiology & Biostatistics and Medical Oncology VUmc  Amsterdam | The Netherlands MedicalResearch.com: What is the background for this study? What are the main findings?  Response: There is evidence from randomized controlled trials that exercise has beneficial effects on physical fitness, fatigue, quality of life and self-reported physical function during and following cancer treatment. The magnitude of the effects, however, often appear modest, possibly because interventions rarely target patients with worse symptoms and quality of life. Based on individual patient data from 34 randomized controlled trials, we found that exercise interventions during cancer treatment are effective in maintaining muscle strength and quality of life, regardless of their baseline values. Offering exercise interventions post cancer treatment to patients with a relatively high muscle strength and quality of life does not appear to further improve these outcomes. For aerobic fitness, exercise interventions during treatment had larger effects in patients with higher baseline aerobic fitness, whereas all patients were able to improve aerobic fitness post treatment. Greater effects on fatigue and self-reported physical function were found for patients with worse baseline fatigue and physical function, both during and post-treatment.  (more…)
Author Interviews, Exercise - Fitness, JAMA, Neurology, Parkinson's / 23.09.2018

MedicalResearch.com Interview with: Fudi Wang, M.D., Ph.D. Qiushi Chair Professor Nutrition Discovery Innovation Center School of Public Health/School of Medicine Zhejiang University Hangzhou 310058, ChinaFudi Wang, M.D., Ph.D. Qiushi Chair Professor Nutrition Discovery Innovation Center School of Public Health/School of Medicine Zhejiang University Hangzhou  China MedicalResearch.com: What is the background for this study? What are the main findings? Response: Parkinson disease (PD) is the second most common neurodegenerative disease affecting approximately 10 million people around the world. To date, the cause of PD remains poorly understood. It is reported that 90% PD cases have no identifiable genetic cause. What’s worse, few therapeutic advances for the treatment of PD have been made in the past decades. Nevertheless, growing prospective longitudinal studies shed lights on the potential beneficial effect of lifestyle factors on reducing the risk of developing Parkinson disease. In this study, we performed a a dose-response meta-analysis of more than half a million participants. We found that physical activity, particularly moderate to vigorous physical activity, could significantly reduce PD risk. (more…)
Author Interviews, Exercise - Fitness, Lifestyle & Health / 18.09.2018

MedicalResearch.com Interview with: “sleeping” by Venturist is licensed under CC BY 2.0Matthieu Boisgontier  PhD Movement Control & Neuroplasticity Research Group KU Leuven Brain Behaviour Laboratory University of British Columbia, Canada MedicalResearch.com: What is the background for this study? What are the main findings? Response: For decades, society has encouraged people to be more physically active. Yet, despite gradually scaling up actions promoting physical activity across the years, we are actually becoming less active. From 2010 to 2016, the number of inactive adults has increased by 5% worldwide, now affecting more than 1 in 4 adults (1.4 billion people). This context raised the question: Why do we still fail to be more physically active? Our hypothesis was that this failure is explained by an “exercise paradox” in which conscious and automatic processes in the brain come into conflict. To illustrate this paradox, you can think of people taking the elevator or escalator when they go to the gym, which does not make sense. This non-sense, this paradox, could be due to the fact that their intention to exercise come into conflict with an automatic attraction to resting in the elevator. (more…)
Author Interviews, Education, Exercise - Fitness / 14.09.2018

“Girl Playing Soccer” by Bold Content is licensed under CC BY 2.0MedicalResearch.com Interview with: Craig Pulling. MSc, PGCE, BA (Hons), FHEA Head of Physical Education University of Chichester MedicalResearch.com: What is the background for this study? Response: Successful perceptual-cognitive skill in team-sports such as football requires players to pick up task-relevant information during the control of action in complex and dynamic situations. It has been proposed that players could perform visual exploratory activity (VEA) to be able to recognise important cues in the playing environment. VEA is defined as: “A body and/or head movement in which the player’s face is actively and temporarily directed away from the ball, seemingly with the intention of looking for teammates, opponents or other environmental objects or events, relevant to perform a subsequent action with the ball” (Jordet, 2005, p.143). Research has suggested that VEA is an important facet of skilled performance in youth and adult football. However, it is currently unknown whether such evidence is commensurate with the views of coaches and whether coaching practices are utilised to develop VEA in training. In order to further current understanding on VEA and coaching practices, the present study developed an online survey to examine: (i) when VEA should be introduced in coaching; (ii) how VEA is delivered by coaches and (iii) how coaches evaluate VEA. Further, this study aimed to explore whether distinct groups of football coaches existed who differed in their approach to the delivery of VEA training and, if so, whether there were differences in the demographics of the coaches across these differentiated groups. (more…)
Aging, Author Interviews, Exercise - Fitness, Geriatrics, JAMA / 10.09.2018

MedicalResearch.com Interview with: Peter A. Harmer, PhD., MPH., ATC., FACSM Professor - Department of Exercise & Health Science Willamette University MedicalResearch.com: What is the background for this study? What are the main findings?  Response: Falls in older adults have long been a significant healthcare problem associated with loss of independence, premature morbidity and mortality, and considerable financial strain on individuals and healthcare systems. With the demographic impact of the Baby Boom generation aging into retirement, this issue is becoming even more critical. Among potential prevention strategies, exercise has been proposed to be beneficial. However, establishing what types of exercise are suitable to the task has been problematic. More importantly, identifying differences in the effectiveness of various exercise approaches has been lacking. (more…)
Author Interviews, CMAJ, Heart Disease, Lifestyle & Health, Stroke / 23.07.2018

MedicalResearch.com Interview with: Dr. Doug Manuel MD, MSc, FRCPC Professor and Senior Scientist Ottawa Hospital Research Institute | L’Institut de Recherche de l’Hôpital d’Ottawa Department of Family Medicine, University of Ottawa Départment de Médicine Familiale Université d’Ottawa  MedicalResearch.com: What is the background for this study? What are the main findings? Response: A lot of people are interested in healthy living, but often we don't have that discussion in the doctor's office," says Dr. Manuel, who is also a professor at the University of Ottawa. "Doctors will check your blood pressure and cholesterol levels, but they don't necessarily ask about lifestyle factors that could put you at risk of a heart attack and stroke. We hope this tool can help people — and their care team — with better information about healthy living and options for reducing their risk of heart attack and stroke." "What sets this cardiovascular risk calculator apart is that it looks at healthy living, and it is better calibrated to the Canadian population," says Dr. Doug Manuel, lead author, senior scientist at The Ottawa Hospital and a senior core scientist at the Institute for Clinical Evaluative Sciences (ICES).”  (more…)
Author Interviews, Exercise - Fitness, Microbiome, UCSF / 12.07.2018

MedicalResearch.com Interview with: James R. Bagley, PhD Assistant Professor of Kinesiology Director, Muscle Physiology Lab Co-Director, Exercise Physiology Lab Research Director, Strength & Conditioning Lab San Francisco State University MedicalResearch.com: What is the background for this study? What are the main findings? Response: The human body contains many billions of bacteria cells, and the type of bacteria in your gastrointestinal tract (termed gut microbiota) has been linked to certain diseases. Most of your gut microbiota falls into two categories: Firmicutes (F) or Bacteroidetes (B). The relative gut F/B ratio has been used to assess microbiota health. Our study was the first to examine potential relationships among F/B ratio and cardiorespiratory fitness, body composition, and diet in healthy young men and women We recruited 37 healthy adults to undergo a battery of physiological tests and collected stool samples to analyze their gut F/B ratio using qPCR. We found that F/B ratio was significantly correlated with cardiorespiratory fitness, but with no other variables. In fact, this correlation was so strong that a person’s fitness level explained ~22% of the variance in their gut bacteria composition. (more…)
Author Interviews, Exercise - Fitness, Genetic Research, Heart Disease / 19.05.2018

MedicalResearch.com Interview with: Prof. Patricia Munroe PhD Professor of Molecular Medicine William Harvey Research Institute Barts and The London School of Medicine and Dentistry Queen Mary University of London MedicalResearch.com: What is the background for this study? Response: Over the years, it has become increasingly evident that impaired capacity to increase heart rate during exercise and reduce heart rate following exercise are important predictors of all-cause and cardiovascular mortality. A person's capability to regulate their heart rate is the result of complex interactions of biological systems, including the autonomic nervous and hormonal systems. Prior work has demonstrated that genetic factors significantly contribute to variations in resting heart rate among different individuals, but less was known about the genetic factors modulating the response of heart rate to exercise and recovery. (more…)
Author Interviews, BMJ, Depression, Exercise - Fitness / 17.05.2018

MedicalResearch.com Interview with: Prof. Sarah E Lamb,  MSc, MA, MCSP, Grad Dip Statistics, DPhil Centre for Rehabilitation Research and Centre for Statistics in Medicine Nuffield Department of Orthopaedics Rheumatology & Musculoskeletal Sciences Botnar Research Centre, University of Oxford, Oxford MedicalResearch.com: What is the background for this study? What are the main findings? Response: Scientists and clinicians have considered the possibility that higher intensity aerobic and muscle strength training might have a beneficial effect in preventing dementia or slowing the progression of cognitive impairment in those who have dementia. The hypothesis has come mostly from animal research. The main findings of our research which used a large sample and high quality methods was that higher intensity exercise, whilst possible, did not slow cognitive impairment. Neither did it have an impact on the functional and behavioural outcomes for people with dementia. It was a substantial commitment for people to participate in the programmes, although many enjoyed the experience and their physical fitness improved. (more…)
Author Interviews, Depression, Exercise - Fitness / 13.05.2018

MedicalResearch.com Interview with: “gym” by FooJFoo is licensed under CC BY-NC-ND 3.0Mr. Brett R. Gordon, M.Sc. Postgraduate researcher Physical Education and Sport Sciences Department University of Limerick, Ireland.  MedicalResearch.com: What is the background for this study? What are the main findings?  Response: Depression is prevalent, burdensome, and often comorbid mood disorder that is associated with other poor health outcomes. Exercise training interventions have demonstrated comparable efficacy for depressive symptoms to frontline treatments, such as antidepressant medications and behavioral therapies. However, the evidence to date has primarily focused on findings from studies of aerobic exercise training like jogging, running, and cycling. Our work is the first quantitative summary of the effects of resistance exercise training (RET), or weight lifting and strength training, on depressive symptoms, and the influence of variables like participant characteristics, features of the RET, and the methods that were used in studies on the antidepressant effects of RET. The main finding was that resistance exercise training significantly reduced depressive symptoms among adults regardless of their health status, the total prescribed volume of RET (e.g., how much the participants were supposed to exercise), or whether or not strength was significantly improved by the RET intervention.  (more…)
Author Interviews, Exercise - Fitness, Nutrition, Weight Research / 01.05.2018

MedicalResearch.com Interview with: Edward "Ted" Weiss, Ph.D. Professor Department of Nutrition and Dietetics Saint Louis University Saint Louis MO 63104 MedicalResearch.com: What is the background for this study? What are the main findings? Response: Ketogenic diets are popular. They are very low in carbohydrate, with moderate protein and large amounts of fat. They are popular for weight loss but definitive studies of this are lacking. We tested the effects of a ketogenic diet on high-intensity exercise performance, such as sprinting. The result showed that the ketogenic diet was harmful to performance, reducing performance by 6 - 7% when compared to a high-carbohydrate diet. (more…)
AHA Journals, Author Interviews, Exercise - Fitness, Heart Disease, NIH / 24.03.2018

MedicalResearch.com Interview with: Pedro F. Saint-Maurice, Ph.D. Postdoctoral Fellow Metabolic Epidemiology Branch Division of Cancer Epidemiology and Genetics National Cancer Institute, NIH, HHS Rockville, MD 20850 MedicalResearch.com: What is the background for this study?  Response: The 2008 Physical Activity Guidelines for Americans recommends adults do 150 minutes/week of moderate intensity physical activity (PA) in increments of at least 10 minutes at a time. However, there is limited epidemiologic evidence supporting the use of the 10-minute increment and whether shorter increments (for instance walking up the stairs) can also be beneficial for health in adults. We looked at accelerometer-measured physical activity in roughly 5,000 adults (40 and older) representative of the US population and followed them prospectively (over 7 years) to determine whether physical activity accumulated in 10-minute increments, but also accumulated in shorter bursts, were associated with lower risk of death (mortality data came from the National Death Index). (more…)
Author Interviews, BMJ, Pain Research, Rheumatology / 22.03.2018

MedicalResearch.com Interview with: “tai chi 11.4.09” by Luigi Scorcia is licensed under CC BY 2.0Chenchen Wang MD, MSc Professor of Medicine Tufts University School of Medicine Director, Center For Complementary And Integrative Medicine Division of Rheumatology Tufts Medical Center Boston, MA 02111  MedicalResearch.com: What is the background for this study? Response: Patients with chronic widespread pain often try many different types of pain medications, anti-depressants, physical therapy, and other approaches, and commonly find that none of these therapies work for them. Finding safe, effective approaches for pain management is an urgent priority. Previous evidence suggested that Tai Chi, a multi-dimensional mind-body practice that integrates physical, psychosocial, and behavioral elements, may be especially suited to address both chronic pain and associated psychological and somatic symptoms. In our most recent study published in the BMJ, we directly compared the effectiveness of Tai Chi versus aerobic exercise, which is a standard care non-drug treatment for fibromyalgia. (more…)
Author Interviews, Diabetes, Duke, Heart Disease / 14.03.2018

MedicalResearch.com Interview with: Stephen J. Greene, MD Division of Cardiology Duke University Medical Center Durham, NC MedicalResearch.com: What is the background for this study? What are the main findings? Response: In 2008, the United States FDA issued an industry guidance specifying that diabetes drugs should routinely be tested in large cardiovascular outcome trials to confirm cardiovascular safety. The guidance specifically mentioned cardiovascular safety in terms of MACE, or major adverse cardiac events, including cardiovascular death, myocardial infarction, and stroke.  Largely because of this, these trials have traditionally had a focus on cardiovascular disease in terms of atherosclerotic events. Heart failure was not mentioned in the FDA document and these trials have had a lesser focus on it. As the years have gone by, we have learned more and more about the connection between diabetes and heart failure. There is tremendous overlap between the two patient populations. Also, as more and more of the large cardiovascular outcome trials have been completed, we have seen multiple examples of various glucose lowering therapies either increasing or decreasing risk of heart failure events. Given all these data on heart failure/ diabetes interactions, the goal of our research was to carefully examine all of the completed large cardiovascular outcome trials of diabetes therapies to systematically describe the type of heart failure-related data they capture. As an initial step in improving heart failure characterization in these trials, we wanted to first describe what trials have already been doing and where the gaps in understanding heart failure in these trials exist. Overall, we found major gaps in the amount and quality of the heart failure data capture in these trials. We looked at 21 large trials, including over 150,000 patients. Rates of patients with baseline heart failure were inconsistently provided, and among those trials that did provide it, heart failure patients tended to be underrepresented compared to the general population. Patients with baseline heart failure were also poorly characterized, with minimal data on functional status, ejection fraction, or heart failure medications. Only 6 trials reported rates of new-onset heart failure and the definitions used were non-specific. Most trials tended to report rates of heart failure hospitalization, but did not include data on fatal or other types of heart failure events. Only 2 trials included heart failure events within the primary study endpoint. More details are included in our full manuscript, which was published in the Journal of the American College of Cardiology to coincide with our presentation at the ACC conference. (more…)
Author Interviews, Exercise - Fitness, Weight Research / 14.02.2018

MedicalResearch.com Interview with: “Elliptical Stationary Bikes GVSU Winter Hall Exercise Center 2-4-15” by Steven Depolo is licensed under CC BY 2.0Jennifer L. Kuk, PhD Associate Professor York University School of Kinesiology and Health Science Sherman Health Science Research Centre Toronto, Ontario MedicalResearch.com: What is the background for this study? What are the main findings? - The benefits of fitness are well know, but it was unclear whether the benefits applied to those with severe obesity. This is even more important give that the health risks associated with severe obesity are exponentially higher than in mild obesity. Fitness in this study was defined as the top 80% of a normal population.This means that unfit is the bottom 20%. In the past, research has shown that this threshold of fitness is associated with the biggest health benefits. - We see that 40% of individuals with mild obesity are fit, while 11% of those with severe obesity are fit. Individuals with high fitness had no differences in health risk, despite the large differences in obesity (~50-100 pounds). Conversely, those within the unfit group did have significantly higher glucose, blood pressure and lipids with higher obesity levels. In other words, fitness was able to protect individuals with severe obesity from many of the expected negative health consequences. (more…)
Accidents & Violence, Author Interviews, Orthopedics / 16.01.2018

MedicalResearch.com Interview with: “First day of snowboarding” by kaolin fire is licensed under CC BY 2.0Dr. Brett D Owens, MD Dr. Owens is currently Team Physician for the US Lacrosse National Men’s Team, and Team Physician for Brown University Professor at Uniformed Services University and Professor at Brown University Alpert School of Medicine MedicalResearch.com: What is the background for this study? What are the main findings? Response: This study is a review of the literature on ski and snowboarding injuries. We summarize findings by our group and others on the injuries seen with these snow sports and report an overall increase in injuries as participation continues to increase. Snowboarders have a higher injury rate and there are different injury patterns with skiers experiencing more lower extremity injuries (knee) and snowboarders experiencing more upper extremity injuries (wrist, shoulder, etc.).  (more…)
Author Interviews, Exercise - Fitness, Supplements / 06.01.2018

MedicalResearch.com Interview with: “Pills Vitamins Macro April 22, 2012 4” by Steven Depolo is licensed under CC BY 2.0Dr Mayur Ranchordas, SFHEA Senior Lecturer in Sport Nutrition and Exercise Metabolism Sport Nutrition Consultant Chair of the Sport and Exercise Research Ethics Group Sheffield Hallam University Academy of Sport and Physical Activity Faculty of Health and Wellbeing Sheffield MedicalResearch.com: What is the background for this study?  Response: People engaging in intense exercise often take antioxidant supplements, such as vitamin C and/or E or antioxidant-enriched foods, before and after exercise in the anticipation that these will help reduce muscle soreness. In a new review published in the Cochrane Library we looked at the evidence from 50 studies. These all compared high-dose antioxidant supplementation with a placebo and their participants all engaged in strenuous exercise that was sufficient to cause muscle soreness. Of the 1089 participants included in the review, nearly nine out of ten of these were male and most participants were recreationally active or moderately trained. (more…)
Aging, Author Interviews, Exercise - Fitness, Geriatrics / 29.11.2017

MedicalResearch.com Interview with: Michael J. LaMonte, PhD, MPH Research Associate Professor Department of Epidemiology and Environmental Health Co-Director, MPH Program (epidemiology) School of Public Health and Health Professions Women’s Health Initiative Clinic University at Buffalo – SUNY  MedicalResearch.com: What is the background for this study? What are the main findings? Response: Current national public health guidelines recommend 150 minutes of moderate to vigorous physical activity a week for adults. The guidelines recommend persons 65 and older follow the adult guidelines to the degree their abilities and conditions allow. Some people, because of age or illness or deconditioning, are not able to do more strenuous activity. Current guidelines do not specifically encourage light activity because the evidence base to support such a recommendation has been lacking. Results from the Objective Physical Activity and Cardiovascular Health (OPACH) Study, an ancillary study to the U.S. Women’s Health Initiative, recently published in the Journal of the American Geriatrics Society showed women ages 65-99 who engaged in regular light intensity physical activities had a reduction in the risk of mortality. The 6,000 women in the OPACH study wore an activity-measuring device called an accelerometer on their hip for seven days while going about their daily activities and were then followed for up to four and a half years.  Results showed that just 30 additional minutes of light physical activity per day lowered mortality risk by 12 percent while 30 additional minutes of moderate activity, such as brisk walking or bicycling at a leisurely pace, exhibited a 39 percent lower risk.  The finding for lower mortality risk associated with light intensity activity truly is remarkable. We anticipated seeing mortality benefit associated with regular moderate-to-vigorous intensity activity, as supported by current public health guidelines. But, observing significantly lower mortality among women who were active at levels only slightly higher than what defines being sedentary was such a novel finding with important relevance to population health. (more…)
AHA Journals, Author Interviews, Brigham & Women's - Harvard, Exercise - Fitness, Lifestyle & Health / 08.11.2017

MedicalResearch.com Interview with: I-Min Lee, MD, ScD Professor of Medicine, Harvard Medical School Professor of Epidemiology, Harvard T.H. Chan School of Public Health Brigham and Women's Hospital Boston, MA 02215 MedicalResearch.com: What is the background for this study? What are the main findings? Response: The fact that physical activity lowers the risk of premature mortality is not a new fact – we have many studies showing this.  However, previous studies have primarily relied on self-reported physical activity, and self-reports tend to be imprecise.  Based on these self-report studies, we know that physical activity is associated with a 20-30% reduction in mortality rates.  And, these self-report studies also have focused on moderate-to-vigorous intensity physical activity, since they are more reliably reported than lighter intensity activity.  We have little information on whether light-intensity activities (e.g., light household chores, very slow walking such as when strolling and window shopping) are associated with lower mortality rates. We now have “wearables” – devices that can more precisely measure physical activity at low (as well as higher) intensities, and sedentary behavior.  The present study, conducted between 2011 and 2015, investigated a large cohort of older women (n=16,741; mean age, 72 years)  who were asked to wear these devices for a week – thus, providing detailed physical activity and sedentary behavior measures.  During an average follow-up of about two-and-a-half years, 207 women died.  The study confirmed that physical activity is related to lower mortality rates. What is new and important is how strong this association is when we have more precise measures of physical activity – the most active women had a 60-70% reduction in mortality rates, compared with the least active, during the study.  For context, non-smokers have about a 50% risk reduction, compared to smokers, which is why patients (and doctors) should pay attention to being physically active. (more…)
Aging, Author Interviews, BMJ, Cost of Health Care, Exercise - Fitness, Social Issues / 27.10.2017

MedicalResearch.com Interview with: Dr. Scarlett McNally Consultant Orthopaedic Surgeo Eastbourne D.G.H. MedicalResearch.com: What is the background for this study? What are the main findings? Response: There are vast differences between older people in their abilities and their number of medical conditions. Many people confuse ageing with loss of fitness. Ageing has specific effects (reduction in hearing and skin elasticity for example) but the loss of fitness is not inevitable. Genetics contributes only 20% to diseases. There is abundant evidence that adults who take up physical activity improve their fitness up to the level of someone a decade younger, with improvements in ‘up and go’ times. Physical activity can reduce the severity of most conditions, such as heart disease or the risk of onset or recurrence of many cancers. Inactivity is one of the top four risk factors for most long-term conditions. There is a dose-effect curve. Dementia, disability and frailty can be prevented, reduced or delayed. The need for social care is based on an individual’s abilities; for example, being unable to get to the toilet in time may increase the need for care from twice daily care givers to needing residential care or live-in care, which increases costs five-fold. Hospitals contribute to people reducing their mobility, with the ‘deconditioning syndrome’ of bed rest, with 60% of in-patients reducing their mobility. The total cost of social care in the UK is up to £100 billion, so even modest changes would reduce the cost of social care by several billion pounds a year. (more…)
Author Interviews, Heart Disease / 20.10.2017

MedicalResearch.com Interview with: Deepika Laddu PhD Assistant Professor Department of Physical Therapy College of Applied Health Sciences The University of Illinois at Chicago Chicago, IL 60612  MedicalResearch.com: What is the background for this study? Response: Recent findings in population-based cohort studies on cumulative exercise dose have caused some controversy and debate showing U-shaped trends of association between physical activity and disease risk. Our objective was to better understand this association between physical activity and cardiovascular disease risk from young adulthood to middle age. Given that engagement in physical activity is a continuously evolving behavior throughout life, this study looked at the physical activity trajectories of 3,175 black and white participants in the multicenter, community-based, longitudinal cohort CARDIA study who reported physical activity patterns over 25 years (from 1985 through 2011), and assessed the presence of coronary artery calcification, or CAC, among participants. Unique to this study is the evaluation of long-term exercise patterns from young adulthood into middle age in CARDIA participants. Based on the trajectories (or patterns of change) of physical activity over 25 years, participants were categorized into three distinct trajectory groups: trajectory group one was defined as exercising below the national guidelines (less than 150 minutes a week), group two as meeting the national guidelines for exercise (150 minutes a week), and group three as exercising three-times the national guidelines (more than 450 minutes a week). (more…)
Author Interviews, Exercise - Fitness, Pain Research, UCSD / 19.10.2017

MedicalResearch.com Interview with: Erik Groessl PhD Associate Adjunct Professor Family Medicine and Public Health University of California, San Diego MedicalResearch.com: What is the background for this study? What are the main findings? Response: Chronic low back pain (cLBP) is prevalent among military veterans, but cLBP treatment options have limited benefits and side effects. This has resulted in efforts to reduce opioid use and embrace nonpharmacological pain treatments. Yoga has been shown to improve health outcomes and have few side effects in non-veteran community samples. Our objective was to study the effectiveness and safety of yoga for military veterans with chronic low back pain. In a study of 150 veterans with cLBP, we found that yoga participants had greater reductions in disability and pain than those receiving usual. Opioid medication use declined among all participants, and no serious side effects occurred. (more…)
Author Interviews, Exercise - Fitness, NEJM, Orthopedics / 04.10.2017

MedicalResearch.com Interview with: Monika Bayer PhD. Institute of Sports Medicine Copenhagen Bispebjerg Hospital Denmark MedicalResearch.com: What is the background for this study? What are the main findings? Response: Acute muscle strain injuries display a major clinical problem with a high incidence rate for both professional and amateur athletes and are associated with substantial risk for recurrence. Common clinical practice advices to follow the RICE (Rest – Ice – Compression – Elevation) principle after strain injuries but it has not been investigated whether patients really benefit from a period of rest or whether an early of loading following the injury would improve recovery. In this study, amateur athletes were divided into two groups: one group started rehabilitation two days after the trauma, the other group waited for one week and began rehabilitation after nine days. All athletes had a clear structural defect of the muscle-connective tissue unit following explosive movements. We found that protraction of rehabilitation onset caused a three-week delay in pain-free recovery. In all athletes included, only one suffered from a re-injury. (more…)
Aging, Author Interviews, Exercise - Fitness / 22.09.2017

MedicalResearch.com Interview with: Dr. Daniel Aggio, PhD UCL Department of Primary Care and Population Health UCL Medical School University College London PA Research Group London, UK MedicalResearch.com: What is the background for this study? What are the main findings? Response: Maintaining a physically active lifestyle into old age is associated with optimal health benefits. While we know that levels of physical activity in youth predict physical activity levels in adulthood, how physical activity in midlife predicts physical activity in old age is not as well understood. It is also unclear how different types of physical activity predict physical activity in later life. Using data from the British Regional Heart Study, an ongoing prospective cohort study involving men recruited between 1978 and 1980, we assessed how physical activity tracks over 20 years from midlife to old age. The study of over 3400 men showed that being active in midlife more than doubled the odds of being active 20 years later. Interestingly, sport participation in midlife predicted physical activity in old age more strongly than other types of physical activity, such as walking and recreational activity. The odds of being active in old age were even stronger for those men who took up sport from a younger age prior to midlife. Sport was the most stable activity across the follow up, with just under half of men reporting playing sport at least occasionally at each survey. However, walking was the least stable; the proportion of men who reported high levels of walking rose from just under 27% at the start of the study to 62% at the 20 year survey, possibly because retirement might free up more time. (more…)
Annals Internal Medicine, Author Interviews, Exercise - Fitness, Heart Disease / 19.09.2017

MedicalResearch.com Interview with: Kevin M. Harris, MD Director, Fellowship Training; Director, Echocardiography Allina Health, Minnesota MedicalResearch.com: What is the background for this study? What are the main findings? Response: Triathlon is a popular endurance sport which combines swimming, bicycling and running. We investigated the death rate in the triathlon since its inception in the United States in 1985 through 2016. Specifically we were able to look at the rate of death in USAT races from 2006 to 2016. We identified 135 deaths/cardiac arrests over the time period. 85% of victims were male and victims averaged 47 years. Most deaths and cardiac arrests occurred in the swim. 15 of the deaths were traumatic occurring during the bike portion. The rate of death was 1.74 per 100,000 participants. The death rate was significantly higher for males than females and increased significantly for men > 40 years. On autopsy, nearly half of those victims were found to have significant cardiovascular disease. (more…)
Author Interviews, CMAJ, Exercise - Fitness, Frailty, Geriatrics, Lifestyle & Health / 21.08.2017

MedicalResearch.com Interview with: Olga Theou, MSc PhD Assistant Professor, Department of Medicine, Dalhousie University Affiliated Scientist, Geriatric Medicine, Nova Scotia Health Authority Adjunct Senior Lecturer, School of Medicine, University of Adelaide Halifax, Nova Scotia  MedicalResearch.com: What is the background for this study? What are the main findings? Response: We already know that moderate to vigorous intensity physical activity, such as time accumulated during exercise, is associated with numerous health benefits. More recent studies also have shown that sedentary time, such as time accumulated during prolonged sitting at work, transportation, and leisure, can also increase the risk of adverse outcomes. What was not known was whether prolonged sitting affects people across different levels of frailty similarly. This is what we examined in our study. We found that there were differences. Low frailty levels (people who are extremely healthy; frailty index score < 0.1) seemed to eliminate the increased risk of mortality associated with prolonged sitting, even among people who did not meet recommended physical activity guidelines. Among people with higher frailty levels, sedentary time was associated with mortality but only among those who did not meet recommended physical activity guidelines (more…)
Author Interviews, Exercise - Fitness, Geriatrics, JAMA / 15.08.2017

MedicalResearch.com Interview with: Jennifer Brach, Ph.D., P.T. Associate professor, Department of physical therapy School of Health and Rehabilitation Sciences University of Pittsburgh MedicalResearch.com: What is the background for this study? What are the main findings? Response: This study compared two different group exercise programs to improve mobility in community-dwelling older adults. The first program, a seated program focused on strength, endurance and flexibility, was based on usual care. The second program, called On the Move, was conducted primarily in standing position and focused on the timing and coordination of movements important for walking. Both programs met two times per week for 12 weeks. It was found that the On the Move program was more effective at improving mobility than the usual seated program. (more…)
Author Interviews, Exercise - Fitness, Technology / 10.07.2017

MedicalResearch.com Interview with: Jacob Barkley, Ph.D., College of Education, Health and Human Services Kent State  MedicalResearch.com: What is the background for this study? Response: Our group has demonstrated that cellular telephone (cell phone) use is positively associated with sedentary behavior (i.e., sitting). To that end, high cell phone users sit for 80 to 100 minutes longer than their lower-use peers. We have also shown that cell phone use during exercise decreases exercise intensity and slows free-living walking speed. In other words, cell use may be comparable to traditional sedentary screen use in that it promotes sitting and may interfere with physical activity. However, some cell phone functions may actually promote positive health behaviors. Fitness apps, connecting with active peers and administering health recommendations via the cell phone all may have utility in promoting physical activity and reducing sedentary behavior. While not well studied, novel physically-interactive cell phone games may also promote physical activity. One such game, Pokémon Go! requires users to walk through real environments and locate avatars in the game using GPS. The purpose of the game is to find these avatars. In order to find more avatars, the player will need to walk to more areas. Therefore, playing Pokémon Go! may promote walking. (more…)