Author Interviews, Diabetes, Diabetologia, Weight Research / 17.05.2014
Two Large Meals May Be Better Than Six Small Meals For Weight, Diabetes Control
MedicalResearch.com Interview with:
Hana Kahleova, MD, PhD
Diabetes Centre, Institute for Clinical and Experimental Medicine
140 21 Prague
Czech Republic
MedicalResearch: What was the aim of your study?
Dr. Kahleova: The aim of the study was to compare the effect of six (A6 regimen) vs two meals a day, breakfast and lunch (B2 regimen), on body weight, hepatic fat content (HFC), insulin resistance and beta cell function.
MedicalResearch: What are the main findings of the study?
Dr. Kahleova: Comparison of the effect of six vs. two meals (breakfast and lunch) with the same daily caloric restriction (-500 kcal/day) and macronutrient content, each regimen lasting 12 weeks, demonstrated a superior effect of breakfast and lunch on body weight, hepatic fat content, fasting plasma glucose, C-peptide, glucagon and insulin sensitivity.
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