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One of the most startling aspects of the connection between schizophrenia and substance abuse is the high prevalence of substance use disorders among those with schizophrenia. Studies consistently show that individuals diagnosed with schizophrenia are more likely to engage in substance abuse compared to the general population. This connection can be best demonstrated using the self-medication hypothesis. According to this hypothesis, individuals with schizophrenia may turn to substances as a way to self-medicate or alleviate their distressing symptoms. Imagine dealing with hallucinations or disorganized thoughts—some may use alcohol or drugs to temporarily escape from this internal turmoil.