Author Interviews, CDC, COVID -19 Coronavirus, JAMA / 08.01.2021
More Than Half of COVID-19 Infections Acquired from Asymptomatic Carriers
MedicalResearch.com Interview with:
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Dr. Butler[/caption]
Jay C. Butler, MD, FAAP, MACP, FIDSA
Deputy Director for Infectious Diseases
Centers for Disease Control and Prevention
Atlanta, GA 30333
MedicalResearch.com: What is the background for this study?
Response: There are still disagreements about the significance of transmission of SARS-CoV-2 from asymptomatic persons. It has been known since at least March 2020 that, unlike the closely related coronavirus that causes SARS, transmission of COVID-19 from asymptomatic and presymptomatic persons occurs and that at least 30% of infected persons do not develop symptoms. Estimating the proportion of transmissions from persons without symptoms informs the decision analysis for prioritization of community mitigations opportunities: wearing of masks, social distancing, and hand hygiene. If only a low proportion of transmission occurs from people without symptoms, these interventions would be less likely to control transmission when broadly applied in the community. On the other hand, if a significant proportion of spread is from infected persons without symptoms, the value of these measures is enhanced.
Additionally, obtaining strategic and systematic screening tests for SARS-CoV-2 to identify and isolate persons without symptoms in selected settings, such as congregational housing settings, will have greater potential impact if spread from persons without symptoms is common.
Dr. Butler[/caption]
Jay C. Butler, MD, FAAP, MACP, FIDSA
Deputy Director for Infectious Diseases
Centers for Disease Control and Prevention
Atlanta, GA 30333
MedicalResearch.com: What is the background for this study?
Response: There are still disagreements about the significance of transmission of SARS-CoV-2 from asymptomatic persons. It has been known since at least March 2020 that, unlike the closely related coronavirus that causes SARS, transmission of COVID-19 from asymptomatic and presymptomatic persons occurs and that at least 30% of infected persons do not develop symptoms. Estimating the proportion of transmissions from persons without symptoms informs the decision analysis for prioritization of community mitigations opportunities: wearing of masks, social distancing, and hand hygiene. If only a low proportion of transmission occurs from people without symptoms, these interventions would be less likely to control transmission when broadly applied in the community. On the other hand, if a significant proportion of spread is from infected persons without symptoms, the value of these measures is enhanced.
Additionally, obtaining strategic and systematic screening tests for SARS-CoV-2 to identify and isolate persons without symptoms in selected settings, such as congregational housing settings, will have greater potential impact if spread from persons without symptoms is common.
CDC PHIL image[/caption]
MedicalResearch.com: What is the background for this study?
Response: This report reviewed three measures of tooth loss among adults over 50 years old with selected chronic conditions. The report analyzed data from the 2011–2016 cycles of the National Health and Nutrition Examination Survey (NHANES) to compare the rates of total tooth loss, severe tooth loss (less than 8 teeth), and lacking functional dentition (less than 20 teeth) among people with and without selected chronic conditions.





