Author Interviews, Cancer Research, Immunotherapy, Nature, Technology, University of Michigan / 27.12.2016
Vaccine Nanodiscs Can Trigger More Cancer Fighting Immune Cells
MedicalResearch.com Interview with:
James Moon, PhD
John Gideon Searle Assistant Professor
University of Michigan
Dept. of Pharmaceutical Sciences and Biomedical Engineering
Biointerfaces Institute
Ann Arbor, MI, 48109
MedicalResearch.com: What is the background for this study?
Response: The field of cancer immunotherapy has recently made a breakthrough with the clinical success of immune checkpoint inhibitors, which work by removing the brakes on immunosuppressed T-cells. However, these approaches generally work by augmenting pre-existing T-cell immunity and benefit only a subset of patients. In addition, because the majority of somatic mutations in cancer cells are unique to each patient, cancer immunotherapy may benefit from a personalized approach.
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