Author Interviews, COVID -19 Coronavirus, Environmental Risks, JAMA / 11.06.2020
Research Suggests Higher Temperature and Humidity Will Make Coronavirus Transmission More Difficult
MedicalResearch.com Interview with:
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Dr. Sajadi[/caption]
Mohammad Sajadi, MD
Associate Professor
Institute of Human Virology
Global Virus Network Center of Excellence
University of Maryland School of Medicine
Baltimore, MD 21201
MedicalResearch.com: What is the background for this study?
Response: Because of geographical proximity and significant travel connections, epidemiological modeling of the epicenter predicted that regions in Southeast Asia, and specifically Bangkok would follow Wuhan, and China in the COVID-19 epidemic. When we saw this did not happen, we suspected that SARS-CoV-2 might be acting like a seasonal respiratory virus.
Dr. Sajadi[/caption]
Mohammad Sajadi, MD
Associate Professor
Institute of Human Virology
Global Virus Network Center of Excellence
University of Maryland School of Medicine
Baltimore, MD 21201
MedicalResearch.com: What is the background for this study?
Response: Because of geographical proximity and significant travel connections, epidemiological modeling of the epicenter predicted that regions in Southeast Asia, and specifically Bangkok would follow Wuhan, and China in the COVID-19 epidemic. When we saw this did not happen, we suspected that SARS-CoV-2 might be acting like a seasonal respiratory virus.
Ning Ding[/caption]
Ning Ding MPH, PhD candidate
[caption id="attachment_54465" align="alignleft" width="141"]
Dr. Wiener and Christopher Waters, Research Labs Director, WVU School of Dentistry[/caption]
R. Constance Wiener, DMD, PhD
Associate Professor
West Virginia University School of Dentistry
MedicalResearch.com: What is the background for this study?
Response: Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are chemical groups that have had a wide variety of uses due to their ability to their ability to repel water and stains. They might be found in food packaging, water-repellant clothing and carpeting, paints, fire-fighting foam, and water, for example. Although many are no longer manufactured in the United States, PFAS persist in the environment as they do not readily break down. Adverse health effects have been speculated especially for low birthweight babies, immunological effects, certain cancers and thyroid hormone disruption.1 With these considerations, we hypothesized that there may be an association of PFAS with tooth development and subsequent dental caries (cavities).
MedicalResearch.com: What is the background for this study?
Response: A prior pilot





Dr. Taioli[/caption]
Emanuela Taioli, MD, PhD,
Director of the Institute for Translational Epidemiology
Icahn School of Medicine at Mount Sinai
Asociate director for Population Science
Tisch Cancer Institute
MedicalResearch.com: What is the background for this study? What are the main findings?
Response: An excess incidence of prostate cancer has been identified among World Trade Center responders. We wanted to study if this excess was associated with exposure to WTC dust
The results suggest that respiratory exposure to WTC dust can induce inflammatory and immune responses in prostate tissue. Chronic inflammation could facilitate prostate cancer development
Taken together, our results suggest that World Trade Center prostate cancer cases have a distinct gene expression pattern that may be the result of exposure to specific carcinogens during the WTC attacks. WTC dust-exposed rat prostate displayed unique changes in gene expression and immune cell infiltrates after acute dust exposure, suggesting that the effect of exposure may be measured locally in target organs such as prostate. In addition, some of the genes overexpressed in rat normal prostates as a consequence of exposure are also overexpressed in human prostate cancer tissues, suggesting a link between exposure, local immune dysregulation, and prostate cancer development

